Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   CWI26_RS04025 Genome accession   NZ_CP025043
Coordinates   780539..781201 (+) Length   220 a.a.
NCBI ID   WP_100881261.1    Uniprot ID   A0A2I5KMY1
Organism   Streptococcus suis strain AH681     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 775539..786201
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CWI26_RS04005 (CWI26_04005) - 775817..776746 (-) 930 WP_100881259.1 ABC transporter substrate-binding protein -
  CWI26_RS04010 (CWI26_04010) - 776759..777544 (-) 786 WP_014636900.1 ABC transporter ATP-binding protein -
  CWI26_RS04015 (CWI26_04015) - 778130..779575 (-) 1446 WP_100881260.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  CWI26_RS04020 (CWI26_04020) - 779723..780469 (+) 747 WP_014735985.1 lysophospholipid acyltransferase family protein -
  CWI26_RS04025 (CWI26_04025) comEA/celA/cilE 780539..781201 (+) 663 WP_100881261.1 helix-hairpin-helix domain-containing protein Machinery gene
  CWI26_RS04030 (CWI26_04030) comEC/celB 781185..783422 (+) 2238 WP_100881262.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23346.86 Da        Isoelectric Point: 4.0936

>NTDB_id=257604 CWI26_RS04025 WP_100881261.1 780539..781201(+) (comEA/celA/cilE) [Streptococcus suis strain AH681]
MNNIKTYIESLKEYKWQIALPAAAGLLMATFLIFSQPAKSDQTGLTEFPQTEQASSSQEQTEETSTEVSEEPSQLVVDVK
GAVEKPGLYTLEAGARVNDAVEAAGGLTSQADPKSVNLAQKLSDEAVVYVASKDENISVVASTTASSAMSQEEKNTSLVN
LNTATEADLQTISGIGAKRAADIIAYREANGGFKSVDDLNNVSGIGDKTMESIRPYVTVD

Nucleotide


Download         Length: 663 bp        

>NTDB_id=257604 CWI26_RS04025 WP_100881261.1 780539..781201(+) (comEA/celA/cilE) [Streptococcus suis strain AH681]
ATGAACAATATTAAAACCTATATAGAAAGCTTAAAAGAATACAAGTGGCAGATTGCCCTGCCCGCAGCGGCTGGTTTGCT
TATGGCGACATTCTTAATTTTCAGCCAACCAGCTAAGTCTGACCAGACAGGACTGACAGAATTTCCTCAAACTGAGCAAG
CTTCTAGCAGTCAGGAGCAGACGGAGGAAACCAGTACAGAAGTAAGTGAGGAACCCAGCCAGCTGGTCGTTGATGTCAAA
GGAGCGGTGGAAAAGCCTGGGCTGTACACCTTAGAAGCTGGTGCGCGTGTCAATGACGCAGTCGAGGCAGCTGGCGGCTT
GACCAGTCAGGCAGATCCCAAGTCTGTCAATCTGGCTCAGAAGCTCAGCGATGAGGCGGTGGTCTATGTGGCCAGCAAGG
ATGAAAATATCTCGGTGGTTGCCAGCACGACTGCCAGCTCTGCCATGTCCCAAGAAGAAAAAAACACCAGTCTAGTCAAT
CTGAATACGGCGACTGAGGCGGACCTACAGACCATTTCGGGTATCGGTGCCAAGCGGGCGGCGGACATTATCGCCTATCG
TGAGGCCAACGGCGGCTTCAAGTCGGTGGACGATCTTAACAATGTTTCGGGCATTGGCGACAAGACCATGGAAAGCATTC
GACCTTATGTCACGGTTGACTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(155-218)

SLBB domain (SLBB)

(76-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2I5KMY1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus mitis NCTC 12261

48.402

99.545

0.482
  comEA/celA/cilE Streptococcus pneumoniae Rx1

48.402

99.545

0.482
  comEA/celA/cilE Streptococcus pneumoniae D39

48.402

99.545

0.482
  comEA/celA/cilE Streptococcus pneumoniae R6

48.402

99.545

0.482
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

48.165

99.091

0.477
  comEA/celA/cilE Streptococcus mitis SK321

46.847

100

0.473
  comEA Streptococcus thermophilus LMD-9

59.877

73.636

0.441
  comEA Bacillus subtilis subsp. subtilis str. 168

39.524

95.455

0.377
  comEA Lactococcus lactis subsp. cremoris KW2

38.249

98.636

0.377

Multiple sequence alignment