Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   CWI26_RS04030 Genome accession   NZ_CP025043
Coordinates   781185..783422 (+) Length   745 a.a.
NCBI ID   WP_100881262.1    Uniprot ID   A0A2I5KMZ4
Organism   Streptococcus suis strain AH681     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 776185..788422
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CWI26_RS04010 (CWI26_04010) - 776759..777544 (-) 786 WP_014636900.1 ABC transporter ATP-binding protein -
  CWI26_RS04015 (CWI26_04015) - 778130..779575 (-) 1446 WP_100881260.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  CWI26_RS04020 (CWI26_04020) - 779723..780469 (+) 747 WP_014735985.1 lysophospholipid acyltransferase family protein -
  CWI26_RS04025 (CWI26_04025) comEA/celA/cilE 780539..781201 (+) 663 WP_100881261.1 helix-hairpin-helix domain-containing protein Machinery gene
  CWI26_RS04030 (CWI26_04030) comEC/celB 781185..783422 (+) 2238 WP_100881262.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene

Sequence

Protein


Download         Length: 745 a.a.        Molecular weight: 84159.24 Da        Isoelectric Point: 8.7208

>NTDB_id=257605 CWI26_RS04030 WP_100881262.1 781185..783422(+) (comEC/celB) [Streptococcus suis strain AH681]
MSRLTKLPCQPIHLAFLAVTAYFAVHSFSLLTIGLLSLLLLVFGFRQGKTVFIKMLPLLALFGLFFGCQKVQWERADQSA
PEQVTTVQVIPDTIEVNGDSLSFRGRADGQTYQVFYKLASKEEQTYFKKLANLVQLEVEAEVSLPTGQRNFKGFDYQAYL
KTQGIYRTVKISAIKKIVPVQSWNVFDWLSSWRRQALVYVKTNFPAPMSHYMTGLLFGELDSDFDQMSDLYSSLGIIHLF
ALSGMQVGFFIDKFRWILLRLGLTKEAVDKLQIPFSIFYAGLTGFSVSVVRSLVQKILGNMGLRKLDNFAVTVFVCLLIL
PRFLLTAGGVLTFTYAFLLTVFDFEDLGQVKKAAVESLSISLGILPVLMTYFYTFQPLSILLTFVFSFVFDVLLLPGLSV
IFLLSPLIKMTWVNGFFVFMEKIIVWVADLGLRPWILGKPSGLVLLLLLVSLFLLYDFHRRKKWLLGLSLVLALLFFITK
HPLENEVTVVDIGQGDSIFLRDMRGRTVLIDVGGRVDFATKEAWQERSSQANAERTLIPYLHSRGVDRIDSLVLTHTDTD
HVGDVLEVAKQVKIGRIYVSPGSLTVPDFVATLKKINVPVHVVKVGDRLPIFDAYLEVLYPDGTGDGGNNDSIVLYGRLL
ETNFLFTGDLEQGELDLIATYPNLPVDVLKAGHHGSKGSSYPEFLDHIGAKIALVSAGENNRYKHPHQETLDRFDNRNIQ
VYRTDQQGAIRFRGWREWRIETVRE

Nucleotide


Download         Length: 2238 bp        

>NTDB_id=257605 CWI26_RS04030 WP_100881262.1 781185..783422(+) (comEC/celB) [Streptococcus suis strain AH681]
ATGTCACGGTTGACTAAGCTCCCCTGCCAGCCCATCCATTTGGCTTTTTTGGCGGTGACGGCCTACTTTGCAGTCCACTC
TTTTTCCCTCTTGACAATAGGCCTGCTGAGTTTGTTGTTGCTGGTCTTTGGATTTCGGCAAGGTAAGACAGTGTTCATCA
AAATGCTGCCGCTTCTAGCCCTGTTTGGACTGTTTTTCGGATGTCAGAAGGTCCAATGGGAGCGGGCAGACCAGTCAGCC
CCAGAGCAAGTCACCACTGTGCAGGTCATTCCAGATACGATTGAAGTAAACGGGGATAGCCTGTCCTTCCGCGGTCGGGC
TGACGGACAAACCTATCAGGTTTTCTACAAATTAGCCAGTAAGGAGGAGCAGACTTATTTTAAAAAGCTGGCAAACCTGG
TCCAGTTAGAAGTGGAAGCAGAAGTCAGCCTGCCAACTGGTCAGCGGAATTTCAAGGGTTTTGACTACCAAGCCTATCTG
AAAACACAGGGCATCTATCGGACAGTCAAGATTTCTGCGATCAAGAAGATTGTCCCTGTCCAGTCGTGGAATGTTTTTGA
CTGGCTATCAAGCTGGCGGAGGCAGGCCTTGGTCTATGTCAAAACCAATTTTCCGGCTCCCATGAGCCACTACATGACAG
GGCTTTTGTTTGGGGAGCTGGATAGTGATTTCGACCAGATGAGCGACCTCTATTCTAGTCTGGGTATCATTCATCTCTTT
GCCCTGTCTGGTATGCAGGTTGGATTTTTCATCGACAAGTTTCGTTGGATTTTACTGCGTTTAGGCTTGACAAAGGAAGC
CGTAGATAAGTTGCAGATTCCCTTTTCAATTTTTTATGCTGGTTTGACAGGCTTTTCTGTGTCGGTGGTGCGGTCCTTGG
TTCAGAAAATTCTGGGTAATATGGGCTTGCGGAAGTTGGATAACTTTGCGGTGACAGTCTTTGTCTGTCTGCTGATACTA
CCCCGATTTTTACTGACAGCTGGCGGTGTCTTGACCTTTACCTATGCTTTCTTGCTGACGGTTTTTGATTTTGAGGACTT
GGGGCAGGTCAAAAAGGCTGCGGTGGAGAGTCTCAGTATTTCGCTGGGAATTTTGCCGGTGCTTATGACCTATTTCTATA
CCTTTCAGCCCTTATCTATCCTCTTGACCTTTGTCTTTTCCTTTGTCTTTGATGTCCTGCTTTTGCCAGGTTTGTCAGTC
ATTTTTCTTTTATCGCCCTTGATTAAGATGACTTGGGTCAACGGATTTTTCGTTTTTATGGAGAAAATCATTGTCTGGGT
GGCGGATTTGGGATTGCGGCCTTGGATACTGGGCAAGCCCTCTGGGCTGGTCCTCTTACTCTTGCTGGTCAGCCTCTTCT
TGCTCTACGATTTCCACAGGAGAAAGAAATGGCTTCTAGGACTGAGCTTGGTCCTCGCTCTGCTATTTTTCATCACCAAA
CACCCGCTGGAAAACGAGGTGACGGTGGTGGACATCGGGCAGGGGGACAGCATCTTTTTGCGGGATATGCGGGGGCGGAC
GGTCTTGATTGATGTGGGCGGTCGGGTCGATTTTGCGACCAAGGAAGCGTGGCAGGAGCGGTCTTCGCAGGCAAATGCAG
AGCGGACTTTGATTCCCTATCTGCATAGTCGGGGCGTGGACAGGATTGATAGTTTGGTCCTGACCCACACCGACACAGAC
CATGTGGGCGATGTGCTGGAAGTGGCGAAGCAGGTGAAAATTGGTCGGATTTACGTATCGCCAGGAAGCCTGACGGTGCC
TGACTTTGTAGCAACTCTGAAAAAAATCAATGTCCCAGTCCATGTGGTGAAAGTGGGCGACCGCTTGCCGATATTTGACG
CCTATCTGGAAGTTCTCTATCCAGATGGGACAGGAGACGGTGGTAATAATGACTCCATTGTTCTCTATGGTCGCTTGCTG
GAAACCAATTTTCTCTTTACAGGGGACTTGGAGCAAGGGGAGTTGGACTTGATAGCAACCTATCCCAATCTGCCTGTTGA
TGTCCTCAAGGCTGGTCACCACGGATCTAAAGGTTCTTCCTATCCTGAATTTCTAGACCATATCGGAGCCAAGATTGCTC
TGGTATCAGCAGGAGAAAATAACCGCTACAAACACCCCCACCAGGAAACCTTGGACCGTTTTGACAACCGGAATATCCAA
GTCTATCGCACAGACCAGCAAGGAGCCATTCGCTTTCGAGGTTGGAGGGAGTGGAGGATTGAAACGGTGAGGGAATGA

Domains

Predicted by InterproScan.

Competence protein (Competence)

(215-461)

Domain of unknown function (DUF4131) (DUF4131)

(27-176)

Metallo-beta-lactamase superfamily (Lactamase_B)

(493-698)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2I5KMZ4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis SK321

54.73

99.329

0.544
  comEC/celB Streptococcus mitis NCTC 12261

53.252

99.06

0.528
  comEC/celB Streptococcus pneumoniae TIGR4

52.368

99.195

0.519
  comEC/celB Streptococcus pneumoniae Rx1

52.097

99.195

0.517
  comEC/celB Streptococcus pneumoniae D39

52.097

99.195

0.517
  comEC/celB Streptococcus pneumoniae R6

52.097

99.195

0.517
  comEC Lactococcus lactis subsp. cremoris KW2

49.799

100

0.499

Multiple sequence alignment