Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   CWI26_RS00425 Genome accession   NZ_CP025043
Coordinates   75900..77081 (+) Length   393 a.a.
NCBI ID   WP_024377701.1    Uniprot ID   A0A0M9FJN1
Organism   Streptococcus suis strain AH681     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 70900..82081
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CWI26_RS00400 (CWI26_00400) mutL 71335..73272 (+) 1938 WP_024377060.1 DNA mismatch repair endonuclease MutL -
  CWI26_RS00405 (CWI26_00405) - 73346..73711 (+) 366 WP_024377061.1 helix-turn-helix domain-containing protein -
  CWI26_RS00410 (CWI26_00410) - 73726..74373 (+) 648 WP_024377062.1 CPBP family intramembrane glutamic endopeptidase -
  CWI26_RS00415 (CWI26_00415) ruvA 74451..75041 (+) 591 WP_024377699.1 Holliday junction branch migration protein RuvA -
  CWI26_RS00420 (CWI26_00420) - 75294..75863 (+) 570 WP_024377700.1 DNA-3-methyladenine glycosylase I -
  CWI26_RS00425 (CWI26_00425) cinA 75900..77081 (+) 1182 WP_024377701.1 competence/damage-inducible protein A Machinery gene
  CWI26_RS00430 (CWI26_00430) recA 77133..78284 (+) 1152 WP_004195473.1 recombinase RecA Machinery gene
  CWI26_RS00435 (CWI26_00435) spx 78444..78842 (+) 399 WP_004195475.1 transcriptional regulator Spx -
  CWI26_RS00440 (CWI26_00440) - 78949..79215 (+) 267 WP_004195477.1 IreB family regulatory phosphoprotein -
  CWI26_RS00445 (CWI26_00445) ruvX 79215..79634 (+) 420 WP_099780101.1 Holliday junction resolvase RuvX -
  CWI26_RS00450 (CWI26_00450) - 79646..79963 (+) 318 WP_004195480.1 DUF1292 domain-containing protein -
  CWI26_RS00455 (CWI26_00455) - 80273..80818 (+) 546 WP_233486261.1 nucleotidyltransferase family protein -
  CWI26_RS00460 (CWI26_00460) comX/sigX 80920..81390 (+) 471 WP_099806645.1 sigma-70 family RNA polymerase sigma factor Regulator

Sequence

Protein


Download         Length: 393 a.a.        Molecular weight: 42994.90 Da        Isoelectric Point: 4.4149

>NTDB_id=257583 CWI26_RS00425 WP_024377701.1 75900..77081(+) (cinA) [Streptococcus suis strain AH681]
MKAELIAVGTEILTGQIINTNAQFLSEKCAELGIDVYFHTAVGDNEQRLLSVLEIASKRSELVILCGGLGPTEDDLTKQT
LATFLGRNLVFDELAMAKLDRFFASRPGRVRTPNNERQAQIVEGSQALQNPAGLAVGGMIEQDGVTYIVLPGPPSELKAM
FSESLLPLLSQSQQQLYSRVLRFFGIGESQLVTVLADLIDKQTDPTLAPYAKVGEVTLRLSTKATSQEEANLRLNQLEEE
ILQHDKLADYFYAYGEDNSLVKTVATRLAEKRQTIAIVEQGTGGLLQAELSLALADQPYFSGGKVIGQLGTESGRLSEEA
DCIRQELQADLGLAVSVFIKPESTEDNVLAKVYLTLATTSGISQKEIDLGGYSWQYLRQLACLQAWDFVRNTL

Nucleotide


Download         Length: 1182 bp        

>NTDB_id=257583 CWI26_RS00425 WP_024377701.1 75900..77081(+) (cinA) [Streptococcus suis strain AH681]
ATGAAAGCAGAACTAATCGCCGTTGGGACGGAGATTTTGACAGGTCAAATCATTAATACCAATGCTCAGTTCCTTTCGGA
GAAATGTGCAGAGCTGGGAATTGATGTTTATTTCCACACAGCTGTTGGAGATAATGAACAGAGGCTTTTGTCTGTACTGG
AGATAGCCAGCAAGCGTAGTGAGCTAGTCATTCTCTGTGGAGGATTGGGTCCAACTGAGGATGACTTGACCAAGCAGACC
CTGGCGACCTTCTTAGGTAGAAATCTTGTGTTTGATGAGTTGGCTATGGCAAAATTAGACCGTTTCTTTGCCAGTCGCCC
AGGTCGTGTCCGTACACCAAATAATGAACGTCAGGCACAGATTGTGGAGGGAAGTCAAGCTTTGCAGAATCCAGCTGGTT
TAGCTGTTGGTGGTATGATTGAGCAAGATGGTGTAACCTATATTGTTTTGCCTGGCCCACCAAGTGAGCTCAAGGCCATG
TTTTCTGAGAGTCTCTTACCTTTACTGTCCCAATCTCAGCAGCAACTTTATTCGCGTGTCCTACGCTTTTTTGGAATTGG
CGAAAGCCAGTTAGTGACTGTTTTGGCGGACTTGATTGACAAGCAGACAGACCCAACTCTTGCTCCTTATGCAAAAGTTG
GAGAGGTGACTTTACGCTTGTCCACCAAAGCGACCAGCCAAGAAGAAGCAAATCTACGTTTGAATCAGTTGGAAGAAGAA
ATCTTACAACATGACAAACTGGCAGACTATTTCTATGCCTACGGAGAGGACAATAGTTTGGTCAAAACGGTAGCGACTCG
TTTGGCGGAGAAAAGACAAACCATTGCTATCGTCGAACAGGGGACAGGTGGTCTCTTGCAAGCTGAATTGAGTTTGGCTT
TGGCTGACCAGCCTTATTTTAGCGGAGGAAAAGTCATCGGTCAGCTAGGGACAGAATCGGGCAGGCTATCAGAGGAAGCT
GACTGCATTCGGCAGGAGCTGCAAGCTGATTTAGGTTTGGCTGTGTCTGTGTTTATCAAACCGGAATCAACAGAGGACAA
CGTACTTGCAAAAGTATACCTCACTTTGGCTACGACCTCGGGTATTTCCCAAAAAGAGATAGATTTAGGTGGTTATTCGT
GGCAATACCTTCGCCAGCTTGCTTGTCTGCAGGCCTGGGATTTTGTACGAAACACTTTGTGA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0M9FJN1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus suis isolate S10

96.692

100

0.967
  cinA Streptococcus mitis SK321

56.25

100

0.595
  cinA Streptococcus pneumoniae TIGR4

56.25

100

0.595
  cinA Streptococcus pneumoniae Rx1

56.25

100

0.595
  cinA Streptococcus pneumoniae R6

56.25

100

0.595
  cinA Streptococcus mutans UA159

56.934

100

0.595
  cinA Streptococcus mitis NCTC 12261

56.01

100

0.593
  cinA Streptococcus pneumoniae D39

56.01

100

0.593
  cinA Bacillus subtilis subsp. subtilis str. 168

41.176

99.491

0.41

Multiple sequence alignment