Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB/cglB   Type   Machinery gene
Locus tag   CO686_RS10190 Genome accession   NZ_CP023507
Coordinates   2047582..2048598 (+) Length   338 a.a.
NCBI ID   WP_096753792.1    Uniprot ID   -
Organism   Streptococcus oralis strain FDAARGOS_367     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2042582..2053598
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CO686_RS10170 (CO686_10170) - 2043001..2044818 (+) 1818 WP_001220892.1 acyltransferase family protein -
  CO686_RS10175 (CO686_10175) nagA 2044959..2046110 (+) 1152 WP_001134442.1 N-acetylglucosamine-6-phosphate deacetylase -
  CO686_RS10180 (CO686_10180) - 2046263..2046628 (+) 366 WP_000286399.1 DUF1033 family protein -
  CO686_RS10185 (CO686_10185) comGA/cglA/cilD 2046693..2047634 (+) 942 WP_096753791.1 competence type IV pilus ATPase ComGA Machinery gene
  CO686_RS10190 (CO686_10190) comGB/cglB 2047582..2048598 (+) 1017 WP_096753792.1 competence type IV pilus assembly protein ComGB Machinery gene
  CO686_RS10195 (CO686_10195) comGC/cglC 2048600..2048923 (+) 324 WP_000735800.1 competence type IV pilus major pilin ComGC Machinery gene
  CO686_RS10200 (CO686_10200) comGD/cglD 2048886..2049320 (+) 435 WP_172844179.1 competence type IV pilus minor pilin ComGD Machinery gene
  CO686_RS10205 (CO686_10205) comGE/cglE 2049283..2049585 (+) 303 WP_000413383.1 competence type IV pilus minor pilin ComGE Machinery gene
  CO686_RS10210 (CO686_10210) comGF/cglF 2049548..2050009 (+) 462 WP_000250700.1 competence type IV pilus minor pilin ComGF Machinery gene
  CO686_RS10215 (CO686_10215) comGG/cglG 2049987..2050400 (+) 414 WP_000265645.1 competence type IV pilus minor pilin ComGG Machinery gene
  CO686_RS10220 (CO686_10220) - 2050433..2051023 (+) 591 WP_000679770.1 class I SAM-dependent methyltransferase -
  CO686_RS10225 (CO686_10225) comYH 2051082..2052035 (+) 954 WP_000345140.1 class I SAM-dependent methyltransferase Machinery gene

Sequence

Protein


Download         Length: 338 a.a.        Molecular weight: 38517.58 Da        Isoelectric Point: 9.5634

>NTDB_id=247898 CO686_RS10190 WP_096753792.1 2047582..2048598(+) (comGB/cglB) [Streptococcus oralis strain FDAARGOS_367]
MDISQVFRLKRKKLATAKQKKIITLFNNLFSSGFHLVEIISFLGRSALLEKDYVAQMHQGLAQGKSFSEMMESLGFSSAI
VTQLSLAEVHGNLHLSLGKIEEYLDNLSKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATQIIGNLPQIF
LGLVLVCSLSLLLALTFYKRSSKMRVFSMLARVPFLGIFVQTYLTAYYAREWGNMISQGMELTQIFQIMQEQGSQLFKEI
GQDLAQALQNGREFSQTIGTYPFFKKELSLIIEYGEVKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQQLVFIFVALIIV
LLYAAMLMPMYQNMEVNF

Nucleotide


Download         Length: 1017 bp        

>NTDB_id=247898 CO686_RS10190 WP_096753792.1 2047582..2048598(+) (comGB/cglB) [Streptococcus oralis strain FDAARGOS_367]
ATGGACATATCACAAGTCTTCAGGCTGAAACGGAAAAAATTAGCTACAGCTAAGCAGAAGAAAATCATCACTTTGTTTAA
CAACCTCTTCTCCAGTGGCTTTCATTTGGTGGAAATTATTTCTTTCTTGGGAAGAAGTGCCCTGCTAGAAAAGGACTATG
TGGCCCAGATGCACCAAGGCTTGGCTCAGGGGAAATCATTCTCAGAAATGATGGAAAGTTTGGGTTTTTCAAGTGCCATT
GTGACCCAATTATCTCTAGCTGAAGTGCATGGAAATCTTCACCTGAGTCTGGGGAAGATAGAAGAATATCTGGATAATTT
GTCCAAGGTCAAGAAGAAGTTAATTGAAGTGGCGACCTATCCCCTGATTTTGCTGGGATTTCTCCTGCTAATCATGCTGG
GGTTGAGAAACTATCTACTTCCCCAACTGGACAGTAGCAATATTGCCACTCAAATCATCGGCAATCTGCCACAAATATTT
CTGGGACTAGTGCTGGTTTGCTCTCTGTCTTTACTTTTAGCCCTCACTTTCTACAAAAGAAGTTCCAAGATGCGGGTTTT
CTCGATGTTGGCACGGGTTCCCTTTCTAGGAATCTTTGTCCAGACCTATCTGACGGCCTATTACGCGCGTGAATGGGGCA
ATATGATTTCGCAGGGAATGGAGCTGACGCAGATTTTTCAGATCATGCAGGAACAAGGTTCCCAGCTCTTTAAAGAAATC
GGTCAAGATCTGGCTCAAGCCCTGCAAAATGGCCGCGAATTTTCTCAGACTATAGGAACCTATCCTTTCTTTAAAAAGGA
GTTGAGTCTCATCATCGAGTATGGGGAAGTCAAGTCCAAGCTGGGGAGTGAGTTGGAAATCTATGCTGAAAAAACTTGGG
AAGCCTTTTTTACCCGAGTTAATCGTACCATGAACTTAGTACAGCAACTGGTTTTTATCTTTGTGGCTCTGATTATCGTT
TTACTTTATGCGGCAATGCTTATGCCCATGTATCAAAATATGGAGGTAAATTTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(209-329)

Type II secretion system (T2SS), protein F (T2SSF)

(24-141)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB/cglB Streptococcus mitis SK321

92.899

100

0.929
  comGB/cglB Streptococcus mitis NCTC 12261

92.604

100

0.926
  comGB/cglB Streptococcus pneumoniae Rx1

91.124

100

0.911
  comGB/cglB Streptococcus pneumoniae D39

91.124

100

0.911
  comGB/cglB Streptococcus pneumoniae R6

91.124

100

0.911
  comGB/cglB Streptococcus pneumoniae TIGR4

91.124

100

0.911
  comYB Streptococcus gordonii str. Challis substr. CH1

73.214

99.408

0.728
  comYB Streptococcus mutans UA140

58.934

94.379

0.556
  comYB Streptococcus mutans UA159

58.934

94.379

0.556
  comGB Lactococcus lactis subsp. cremoris KW2

52.071

100

0.521

Multiple sequence alignment