Detailed information NTG0247904

Bioinformatically predicted

Overview

• Name: comYH
• Type: Machinery gene
• Locus tag: CO686_RS10225
• Genome accession: NZ_CP023507
• Coordinates: 2051082..2052035 (+)
• Length: 317 a.a.
• NCBI ID: WP_000345140.1
• Uniprot ID: A0AAW7W9V9
• Organism: Streptococcus oralis strain FDAARGOS_367
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2046082..2057035

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CO686_RS10180 (CO686_10180)	-	2046263..2046628 (+)	366	WP_000286399.1	DUF1033 family protein	-
CO686_RS10185 (CO686_10185)	comGA/cglA/cilD	2046693..2047634 (+)	942	WP_096753791.1	competence type IV pilus ATPase ComGA	Machinery gene
CO686_RS10190 (CO686_10190)	comGB/cglB	2047582..2048598 (+)	1017	WP_096753792.1	competence type IV pilus assembly protein ComGB	Machinery gene
CO686_RS10195 (CO686_10195)	comGC/cglC	2048600..2048923 (+)	324	WP_000735800.1	competence type IV pilus major pilin ComGC	Machinery gene
CO686_RS10200 (CO686_10200)	comGD/cglD	2048886..2049320 (+)	435	WP_172844179.1	competence type IV pilus minor pilin ComGD	Machinery gene
CO686_RS10205 (CO686_10205)	comGE/cglE	2049283..2049585 (+)	303	WP_000413383.1	competence type IV pilus minor pilin ComGE	Machinery gene
CO686_RS10210 (CO686_10210)	comGF/cglF	2049548..2050009 (+)	462	WP_000250700.1	competence type IV pilus minor pilin ComGF	Machinery gene
CO686_RS10215 (CO686_10215)	comGG/cglG	2049987..2050400 (+)	414	WP_000265645.1	competence type IV pilus minor pilin ComGG	Machinery gene
CO686_RS10220 (CO686_10220)	-	2050433..2051023 (+)	591	WP_000679770.1	class I SAM-dependent methyltransferase	-
CO686_RS10225 (CO686_10225)	comYH	2051082..2052035 (+)	954	WP_000345140.1	class I SAM-dependent methyltransferase	Machinery gene

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 35525.50 Da
• Isoelectric Point: 4.2230

>NTDB_id=247904 CO686_RS10225 WP_000345140.1 2051082..2052035(+) (comYH) [Streptococcus oralis strain FDAARGOS_367]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETEQKQVKENNQALKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVLIVEELLDQEEISILEIGSGMGILGATFLTSLAKKVDYLGIEVDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAIASRYQVASSQEHTYAHHLLMEQGFKYLKSNGYAIFLAPSDLLTSPQ
SDSLKGWLKDEVSLAAIIALPEDIFSTASQAKSIFVLQKKRDKEIEPFVYPLTSLQDPSVLLTFKENFQNWSKGTEI

Nucleotide

• Length: 954 bp

>NTDB_id=247904 CO686_RS10225 WP_000345140.1 2051082..2052035(+) (comYH) [Streptococcus oralis strain FDAARGOS_367]
ATGGATTTTGAAAAAATTGAACAAGCTTATACGTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGATGCCTTAGTAGAGCAAAACAGCATTTATCTAGATGGCGAGACTGAGCAAAAGCAGGTCAAGGAGAACAATC
AAGCCCTTAAGCGCTTAGCACTTCGCAAGGAAGAGTGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCGGGACAAACG
GAGCCTTTACAGGCCAATCACCAGTTTACGCCGGATGCCATTGCCCTCCTCTTGGTACTTATTGTGGAAGAGTTGCTGGA
TCAAGAGGAAATTAGCATCCTCGAAATAGGTTCTGGTATGGGGATTTTGGGGGCTACTTTCTTGACTTCTCTTGCTAAAA
AAGTAGATTACTTGGGAATCGAAGTGGATGACTTGCTGATTGATTTGGCAGCCAGTATGGCAGATGTGATTGGTTTGCAG
GCTGGTTTTGTCCAAGGAGATGCCGTTCGTCCGCAAATGCTTAAAGAAAGCGACGTGGTCATCAGCGACTTGCCTGTAGG
CTATTACCCAGACGATGCCATCGCTTCTCGCTATCAAGTGGCTTCTAGTCAAGAGCATACCTATGCCCACCATTTGCTGA
TGGAACAAGGCTTCAAGTACCTTAAGTCAAATGGCTATGCTATTTTTCTAGCTCCGAGTGATTTATTGACCAGCCCTCAA
AGTGACTCATTAAAAGGGTGGCTCAAAGACGAAGTGAGTCTGGCTGCTATCATCGCTCTGCCAGAGGATATTTTCTCAAC
TGCAAGCCAAGCTAAAAGTATTTTTGTCTTACAGAAGAAAAGAGACAAGGAAATAGAACCCTTTGTCTACCCTCTTACTA
GCTTGCAAGATCCGTCAGTTTTGTTGACCTTTAAAGAAAATTTTCAAAATTGGAGCAAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

• N-6 DNA Methylase (N6_Mtase) (69-283)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYH	Streptococcus mutans UA140	57.556	98.107	0.565
comYH	Streptococcus mutans UA159	57.235	98.107	0.562