Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGF/cglF   Type   Machinery gene
Locus tag   CO686_RS10210 Genome accession   NZ_CP023507
Coordinates   2049548..2050009 (+) Length   153 a.a.
NCBI ID   WP_000250700.1    Uniprot ID   A0AAW7WA27
Organism   Streptococcus oralis strain FDAARGOS_367     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2044548..2055009
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CO686_RS10175 (CO686_10175) nagA 2044959..2046110 (+) 1152 WP_001134442.1 N-acetylglucosamine-6-phosphate deacetylase -
  CO686_RS10180 (CO686_10180) - 2046263..2046628 (+) 366 WP_000286399.1 DUF1033 family protein -
  CO686_RS10185 (CO686_10185) comGA/cglA/cilD 2046693..2047634 (+) 942 WP_096753791.1 competence type IV pilus ATPase ComGA Machinery gene
  CO686_RS10190 (CO686_10190) comGB/cglB 2047582..2048598 (+) 1017 WP_096753792.1 competence type IV pilus assembly protein ComGB Machinery gene
  CO686_RS10195 (CO686_10195) comGC/cglC 2048600..2048923 (+) 324 WP_000735800.1 competence type IV pilus major pilin ComGC Machinery gene
  CO686_RS10200 (CO686_10200) comGD/cglD 2048886..2049320 (+) 435 WP_172844179.1 competence type IV pilus minor pilin ComGD Machinery gene
  CO686_RS10205 (CO686_10205) comGE/cglE 2049283..2049585 (+) 303 WP_000413383.1 competence type IV pilus minor pilin ComGE Machinery gene
  CO686_RS10210 (CO686_10210) comGF/cglF 2049548..2050009 (+) 462 WP_000250700.1 competence type IV pilus minor pilin ComGF Machinery gene
  CO686_RS10215 (CO686_10215) comGG/cglG 2049987..2050400 (+) 414 WP_000265645.1 competence type IV pilus minor pilin ComGG Machinery gene
  CO686_RS10220 (CO686_10220) - 2050433..2051023 (+) 591 WP_000679770.1 class I SAM-dependent methyltransferase -
  CO686_RS10225 (CO686_10225) comYH 2051082..2052035 (+) 954 WP_000345140.1 class I SAM-dependent methyltransferase Machinery gene

Sequence

Protein


Download         Length: 153 a.a.        Molecular weight: 17712.41 Da        Isoelectric Point: 9.8338

>NTDB_id=247902 CO686_RS10210 WP_000250700.1 2049548..2050009(+) (comGF/cglF) [Streptococcus oralis strain FDAARGOS_367]
MVQRNCSILKSSKVRAFTLLESLIALIVISGGLLLFQAMSQLLISEVRYQQQSEQKEWLLFVDQLEAELERSQFEKVEGN
RLYMKQDGKDISIGKSKSDDFRKTDASGRGYQPMVYGLKSAQITEGNQLVRFRFQFQKGLEREFIYRVEKAKS

Nucleotide


Download         Length: 462 bp        

>NTDB_id=247902 CO686_RS10210 WP_000250700.1 2049548..2050009(+) (comGF/cglF) [Streptococcus oralis strain FDAARGOS_367]
ATGGTTCAGAGAAATTGCTCGATCTTAAAGAGCAGTAAGGTAAGAGCTTTCACTCTTTTAGAATCTCTGATTGCCCTTAT
CGTCATTAGCGGAGGTTTGCTACTTTTTCAAGCTATGAGTCAGCTCCTCATTTCAGAAGTTCGTTACCAGCAGCAAAGCG
AGCAAAAAGAGTGGCTCTTGTTTGTGGATCAACTGGAGGCAGAGTTAGAGCGTTCGCAGTTTGAAAAGGTAGAAGGCAAT
CGCCTCTACATGAAACAGGATGGTAAGGATATCTCTATAGGGAAATCTAAATCGGATGATTTTCGGAAGACCGATGCCAG
CGGACGGGGCTACCAACCTATGGTTTATGGACTTAAATCAGCTCAAATTACAGAGGGAAATCAACTGGTTCGCTTCCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGCAAAAAGTTAA

Domains

Predicted by InterproScan.

Putative Competence protein ComGF (ComGF)

(45-141)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGF/cglF Streptococcus mitis SK321

91.503

100

0.915
  comGF/cglF Streptococcus mitis NCTC 12261

89.542

100

0.895
  comGF/cglF Streptococcus pneumoniae Rx1

88.235

100

0.882
  comGF/cglF Streptococcus pneumoniae D39

88.235

100

0.882
  comGF/cglF Streptococcus pneumoniae R6

88.235

100

0.882
  comGF/cglF Streptococcus pneumoniae TIGR4

88.235

100

0.882
  comGF Lactococcus lactis subsp. cremoris KW2

40

91.503

0.366

Multiple sequence alignment