Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   CO686_RS07970 Genome accession   NZ_CP023507
Coordinates   1629845..1631101 (-) Length   418 a.a.
NCBI ID   WP_000642672.1    Uniprot ID   A0A291DB37
Organism   Streptococcus oralis strain FDAARGOS_367     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1624845..1636101
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CO686_RS07945 (CO686_07945) - 1625336..1626052 (-) 717 WP_000532893.1 YebC/PmpR family DNA-binding transcriptional regulator -
  CO686_RS07950 (CO686_07950) - 1626149..1627519 (-) 1371 WP_096753705.1 MATE family efflux transporter -
  CO686_RS07955 (CO686_07955) - 1627629..1628183 (+) 555 WP_001054828.1 GNAT family N-acetyltransferase -
  CO686_RS07960 (CO686_07960) - 1628315..1628509 (-) 195 WP_000415527.1 PspC domain-containing protein -
  CO686_RS07965 (CO686_07965) recA 1628639..1629790 (-) 1152 WP_001085520.1 recombinase RecA Machinery gene
  CO686_RS07970 (CO686_07970) cinA 1629845..1631101 (-) 1257 WP_000642672.1 competence/damage-inducible protein A Machinery gene
  CO686_RS07975 (CO686_07975) - 1631174..1632214 (-) 1041 WP_000592175.1 LCP family protein -
  CO686_RS07980 (CO686_07980) - 1632219..1632740 (-) 522 WP_000455513.1 GNAT family N-acetyltransferase -
  CO686_RS07985 (CO686_07985) tsaE 1632730..1633173 (-) 444 WP_000556959.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  CO686_RS07990 (CO686_07990) comM 1633257..1633880 (-) 624 WP_049501270.1 hypothetical protein Regulator
  CO686_RS07995 (CO686_07995) ndk 1634015..1634434 (-) 420 WP_049501265.1 nucleoside-diphosphate kinase -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45160.49 Da        Isoelectric Point: 4.9122

>NTDB_id=247878 CO686_RS07970 WP_000642672.1 1629845..1631101(-) (cinA) [Streptococcus oralis strain FDAARGOS_367]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGDNEARLLSLLEIASQRSNLVILTGGLGPTEDDLTKQT
LAKFLGKDLVFDPQAQEKLDIFFAHRPDYARTPNNERQAQIVEGATPLPNETGLAVGGVSEVDGVTYVVLPGPPSELKPM
VLNQLLPKLMTGTKLYSRVLRFFGIGESQLVTILADLIDHQTDPTLAPYAKTGEVTLRLSTKAVSQEKADQALDILENQI
LSRQTFEGISLRDICYGYGEETSLASVVVEELKKRQKSITAAESLTAGLFQATLADFSGVSAIFNGGFVTYSLEEKSKML
DISEQELKEHGVVSEFTARKMAEQARIKTQSDYGVSLTGVAGPDSLEGHPAGTVFIGLAHAKGTEVIKANIAGRSRADVR
HIAVMHAFNLVRKALLSD

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=247878 CO686_RS07970 WP_000642672.1 1629845..1631101(-) (cinA) [Streptococcus oralis strain FDAARGOS_367]
ATGAAAGCAGAAATTATTGCTGTCGGAACAGAAATTTTAACAGGGCAGATTGTCAATACCAATGCTCAGTTTTTATCAGA
GAAACTAGCCGAAATCGGGGTAGATGTCTATTTCCAAACTGCTGTTGGAGATAATGAAGCTCGTCTTTTGTCCTTGCTGG
AGATTGCGAGCCAACGTAGTAATCTTGTGATTTTGACAGGGGGCTTGGGACCAACTGAGGATGATTTGACCAAACAAACC
CTGGCAAAATTTTTAGGAAAAGATCTAGTGTTTGACCCTCAAGCGCAAGAGAAACTGGATATTTTCTTTGCTCATAGACC
TGACTATGCTCGGACACCGAATAATGAGCGCCAAGCCCAAATTGTAGAAGGGGCGACTCCACTGCCAAATGAGACAGGTT
TAGCAGTAGGAGGGGTGTCGGAAGTGGATGGCGTGACCTACGTGGTCCTCCCGGGACCACCTAGTGAATTGAAACCTATG
GTCTTAAATCAACTCTTACCTAAGTTAATGACTGGTACCAAGTTATACTCACGTGTGCTCCGTTTCTTTGGAATTGGGGA
GAGTCAGTTGGTGACCATTTTGGCGGATTTGATTGACCATCAAACCGATCCGACTTTGGCGCCGTATGCCAAAACAGGAG
AAGTGACCTTGCGCTTGTCTACAAAAGCAGTTAGTCAAGAAAAGGCTGATCAAGCGCTGGATATCTTAGAAAATCAAATC
TTGAGTCGCCAAACTTTCGAGGGAATTTCTTTACGAGACATCTGTTACGGATATGGGGAAGAAACCAGCCTCGCAAGTGT
CGTTGTAGAAGAGCTAAAGAAGAGACAGAAAAGCATTACTGCGGCAGAAAGCTTGACGGCAGGTCTCTTTCAAGCGACAT
TAGCAGACTTTTCGGGCGTTTCAGCAATCTTTAATGGCGGTTTTGTCACTTACAGCCTAGAAGAAAAGTCCAAGATGTTG
GATATTTCCGAGCAAGAGCTAAAAGAACACGGGGTTGTTTCTGAGTTTACGGCTCGAAAAATGGCAGAGCAGGCACGGAT
CAAGACTCAGTCTGATTATGGAGTCAGTCTGACAGGTGTAGCTGGGCCAGATAGCCTAGAGGGTCATCCAGCTGGTACAG
TTTTTATTGGACTGGCACATGCCAAAGGGACAGAGGTGATCAAGGCTAATATCGCAGGACGGAGTCGAGCAGATGTCCGA
CATATTGCGGTCATGCATGCCTTTAACCTAGTTCGCAAGGCTTTATTAAGTGACTAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(177-243)

Competence-damaged protein (CinA)

(262-414)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A291DB37

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

90.191

100

0.902
  cinA Streptococcus pneumoniae TIGR4

89.713

100

0.897
  cinA Streptococcus pneumoniae Rx1

89.713

100

0.897
  cinA Streptococcus pneumoniae R6

89.713

100

0.897
  cinA Streptococcus mitis NCTC 12261

89.474

100

0.895
  cinA Streptococcus pneumoniae D39

89.474

100

0.895
  cinA Streptococcus mutans UA159

70.574

100

0.706
  cinA Streptococcus suis isolate S10

55.048

99.522

0.548
  cinA Bacillus subtilis subsp. subtilis str. 168

45.455

100

0.455

Multiple sequence alignment