Detailed information NTG0229625

Bioinformatically predicted

Overview

• Name: pilQ
• Type: Machinery gene
• Locus tag: CA924_RS05140
• Genome accession: NZ_CP021281
• Coordinates: 1087365..1089461 (+)
• Length: 698 a.a.
• NCBI ID: WP_011213357.1
• Uniprot ID: A0A3A6W2J6
• Organism: Legionella pneumophila subsp. pneumophila strain Flint
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1082365..1094461

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CA924_RS05115	-	1083127..1084134 (-)	1008	WP_011213352.1	hypothetical protein	-
CA924_RS05120	pilM	1084551..1085615 (+)	1065	WP_011213353.1	type IV pilus assembly protein PilM	Machinery gene
CA924_RS05125	pilN	1085619..1086167 (+)	549	WP_011213354.1	PilN domain-containing protein	Machinery gene
CA924_RS05130	pilO	1086181..1086780 (+)	600	WP_011213355.1	type 4a pilus biogenesis protein PilO	Machinery gene
CA924_RS05135	pilP	1086777..1087361 (+)	585	WP_011213356.1	pilus assembly protein PilP	Machinery gene
CA924_RS05140	pilQ	1087365..1089461 (+)	2097	WP_011213357.1	type IV pilus secretin PilQ	Machinery gene
CA924_RS05145	aroK	1089907..1090434 (+)	528	WP_010946667.1	shikimate kinase AroK	-
CA924_RS05150	aroB	1090421..1091530 (+)	1110	WP_011213358.1	3-dehydroquinate synthase	-
CA924_RS05155	-	1091527..1092978 (+)	1452	WP_011213359.1	SPOR domain-containing protein	-
CA924_RS05160	-	1093087..1093518 (+)	432	WP_011213360.1	universal stress protein	-

Sequence

Protein

• Length: 698 a.a.
• Molecular weight: 77455.69 Da
• Isoelectric Point: 9.4307

>NTDB_id=229625 CA924_RS05140 WP_011213357.1 1087365..1089461(+) (pilQ) [Legionella pneumophila subsp. pneumophila strain Flint]
MRKIIAILILISASLSLAYSKDNSLISVQVLPLPENRVRIDFQFSKPLKQLPASFITQKPPRLVLDFISTDMQIPSDQKT
KTIQLGSLHSYNIVAVGDRVRAILELDRSVSYSGSTAGSVYSLVLNGKSNDLFENSKEVFITNQVVNAKHEIKRIDFRGI
EKQGGRVLIDVSDTGIPIDVTQVGKEIVVNFLNTKIPLNLMKRYDVSDFHSPVQIITMQQEGKKVRMTILSKGDYGHFVY
QVNKQFMVDVFPLTAEEIRQAKLKKQVFTGKRISLNFQNISIRAVLQLLADFTGINMVVSDKVQGDITLRLNDIPWDQAL
DIILTTQGLDKRRKGNVMLIDTKASMDKMEEEQLKSQQTIEKLEPIRSDLIQINYAKAADIAVLIKDKQNSLLSDRGKIS
VDARTNTIWIQDTGTKIEEVRELIKQLDIPVKQVLIEARIVEVTKDFSQDIGIRWGVSRPTHLSGTLEGANELARGTAPA
NVVPLERRLNLDLAAAPLTGATPASVGIALAKLNDNILLDLELSALESEGRAELISSPRLITTNQQAAVIESGEEIPYQE
ATSSGATAVAFKKAVLSLKVTPQITPDGKILMDLQINQDTPSPQTFLGVPAIITKEIQTNVLVNNGQTIVLGGIYKQDKN
KVINRIPFFGELPVVGILFSNRQITLKNEELLIFITPRIITNALSITTIEGREKDVYK

Nucleotide

• Length: 2097 bp

>NTDB_id=229625 CA924_RS05140 WP_011213357.1 1087365..1089461(+) (pilQ) [Legionella pneumophila subsp. pneumophila strain Flint]
GTGAGAAAAATTATCGCGATTTTGATATTAATTAGTGCCAGTTTGAGCCTGGCATATTCTAAAGATAATTCGCTCATTTC
AGTACAAGTATTGCCATTGCCCGAAAACAGAGTACGTATTGATTTTCAATTTTCCAAGCCCTTAAAGCAGTTGCCCGCAA
GCTTTATTACTCAAAAGCCGCCTCGTTTGGTGTTAGATTTTATCAGCACTGATATGCAAATTCCTTCGGATCAGAAAACT
AAAACTATTCAATTAGGCTCATTACACAGTTATAACATTGTTGCTGTTGGTGATAGAGTAAGAGCCATATTAGAACTGGA
TCGTTCAGTGTCCTATTCTGGCAGTACGGCTGGTTCCGTTTATAGCCTTGTCCTGAATGGTAAAAGCAATGATTTATTTG
AAAATAGCAAGGAGGTATTCATAACGAACCAGGTTGTGAACGCCAAGCATGAAATTAAAAGAATTGATTTTCGTGGTATA
GAAAAGCAGGGAGGTAGAGTTTTAATTGATGTTTCTGATACGGGTATTCCAATTGATGTAACTCAAGTTGGGAAAGAAAT
AGTCGTTAATTTCTTGAATACCAAGATCCCTTTGAATTTAATGAAACGGTATGATGTTTCTGATTTTCACAGCCCTGTGC
AGATTATTACGATGCAACAGGAAGGCAAAAAGGTTCGCATGACCATCCTCAGCAAAGGGGATTATGGGCATTTTGTTTAT
CAGGTCAATAAACAATTTATGGTCGATGTCTTTCCTTTAACTGCGGAAGAAATTCGTCAGGCGAAATTGAAGAAACAGGT
ATTTACCGGTAAACGGATTTCTTTGAATTTCCAGAATATTAGTATTCGAGCTGTGCTTCAACTTCTGGCAGATTTTACCG
GAATCAATATGGTTGTCAGTGACAAAGTGCAAGGAGATATTACGCTTAGATTAAATGATATCCCCTGGGATCAGGCTCTT
GATATTATTTTAACCACACAAGGGCTAGATAAGCGCAGAAAGGGCAACGTCATGTTGATAGATACCAAAGCCTCCATGGA
TAAAATGGAGGAAGAACAACTCAAAAGTCAACAGACAATTGAAAAACTTGAGCCTATCCGCTCTGATTTAATACAGATTA
ATTATGCAAAGGCAGCAGATATTGCTGTTTTGATCAAGGATAAGCAAAACTCCCTATTATCAGACAGAGGAAAAATAAGT
GTTGATGCCAGAACGAATACAATCTGGATTCAGGATACTGGCACCAAAATTGAGGAAGTAAGGGAACTGATAAAGCAATT
GGATATCCCTGTTAAGCAAGTGCTTATTGAGGCAAGAATTGTTGAAGTAACTAAAGATTTTAGCCAGGATATTGGAATAC
GCTGGGGGGTATCAAGACCAACTCACTTAAGTGGTACACTGGAAGGTGCTAATGAGTTAGCGAGAGGCACAGCACCAGCC
AATGTTGTCCCCTTGGAAAGAAGGTTAAATCTTGATTTGGCAGCTGCTCCTTTAACTGGAGCTACACCGGCCTCGGTAGG
TATTGCGCTAGCTAAACTTAATGATAACATTCTGCTTGATCTGGAGTTGTCTGCTTTGGAAAGCGAAGGGCGTGCTGAAT
TAATATCCAGTCCTCGCCTGATTACTACGAATCAACAGGCAGCAGTCATAGAGTCTGGTGAGGAGATTCCCTATCAGGAG
GCAACATCAAGTGGAGCGACTGCTGTTGCATTTAAAAAAGCAGTATTGAGTTTGAAAGTTACGCCGCAAATTACGCCTGA
TGGTAAAATTTTGATGGATTTACAGATAAATCAGGATACTCCTTCCCCACAAACATTCCTTGGTGTTCCAGCGATAATAA
CAAAGGAGATTCAGACGAATGTTCTGGTTAATAATGGACAAACCATAGTACTTGGAGGTATTTATAAGCAAGATAAGAAC
AAGGTAATCAATAGAATTCCTTTCTTTGGTGAGTTGCCTGTTGTCGGTATTTTATTTAGTAATAGACAAATCACATTGAA
AAATGAAGAGTTACTTATTTTTATTACACCAAGAATAATAACGAATGCCTTATCGATTACAACGATAGAGGGACGTGAGA
AAGATGTTTATAAATAA

Domains

Predicted by InterproScan.

• Bacterial type II and III secretion system protein (Secretin) (525-680)

• Bacterial type II/III secretion system short domain (Secretin_N) (370-433)

• AMIN domain (AMIN) (42-113)

3D structure

• AlphaFold DB: A0A3A6W2J6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilQ	Legionella pneumophila strain ERS1305867	99.713	100	0.997
pilQ	Legionella pneumophila strain Lp02	99.57	100	0.996
pilQ	Pseudomonas aeruginosa PAK	37.872	100	0.383
comQ	Acinetobacter baylyi ADP1	38.574	98.424	0.38
pilQ	Acinetobacter baumannii strain A118	35.014	100	0.368
pilQ	Acinetobacter baumannii D1279779	35.014	100	0.368