Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   GBS_RS11090 Genome accession   NC_004368
Coordinates   187187..188158 (+) Length   323 a.a.
NCBI ID   WP_000250808.1    Uniprot ID   -
Organism   Streptococcus agalactiae NEM316     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 182187..193158
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GBS_RS01065 (gbs0157) rpoC 182885..186535 (+) 3651 WP_000228729.1 DNA-directed RNA polymerase subunit beta' -
  GBS_RS01070 (gbs0158) - 186649..187014 (+) 366 WP_000285373.1 DUF1033 family protein -
  GBS_RS11090 comYA 187187..188158 (+) 972 WP_000250808.1 competence type IV pilus ATPase ComGA Machinery gene
  GBS_RS01075 (gbs0160) comYB 188052..189095 (+) 1044 WP_223295592.1 competence type IV pilus assembly protein ComGB Machinery gene
  GBS_RS01080 (gbs0161) comGC/cglC 189092..189421 (+) 330 WP_000793380.1 competence type IV pilus major pilin ComGC Machinery gene
  GBS_RS01085 (gbs0162) comYD 189396..189809 (+) 414 WP_000244259.1 competence type IV pilus minor pilin ComGD Machinery gene
  GBS_RS01090 (gbs0163) comGE 189781..190080 (+) 300 WP_001867089.1 competence type IV pilus minor pilin ComGE -
  GBS_RS01095 (gbs0164) comGF 190034..190495 (+) 462 WP_001874060.1 competence type IV pilus minor pilin ComGF -
  GBS_RS01100 (gbs0165) comGG 190473..190844 (+) 372 WP_000601104.1 competence type IV pilus minor pilin ComGG -
  GBS_RS01105 (gbs0166) comYH 190959..191933 (+) 975 WP_001008570.1 class I SAM-dependent methyltransferase Machinery gene
  GBS_RS01110 (gbs0167) - 191965..193158 (+) 1194 WP_000047535.1 acetate kinase -

Sequence

Protein


Download         Length: 323 a.a.        Molecular weight: 36779.23 Da        Isoelectric Point: 6.8469

>NTDB_id=22485 GBS_RS11090 WP_000250808.1 187187..188158(+) (comYA) [Streptococcus agalactiae NEM316]
MVQSLAKQVIHQAVEVNAQDIYIIPKGDCYELYMRIDDERRFIDVFEFNRMASLISHFKFVAGMNVGEKRRSQLGSCDYE
LSEGRLVSLRLSSVGDYRGQESLVIRILYSGHQDLKYWFDNIKQMKEVLGTRGLYLFSGPVGSGKTTLMYQLASEVFKNK
QIITIEDPVEIKNDKMLQLQLNEDIGMTYDALIKLSLRHRPDILIIGEIRDQATARAVIRASLTGVMVFSTIHAKSISGV
YDRLIELGVNYQELENSLKLIAYQRLIGGGSLIDFETGNFKKHSSDKWNRQVDILAEEGHISKKQAQVEKIIPQETTESS
PTF

Nucleotide


Download         Length: 972 bp        

>NTDB_id=22485 GBS_RS11090 WP_000250808.1 187187..188158(+) (comYA) [Streptococcus agalactiae NEM316]
ATGGTTCAATCATTAGCAAAGCAAGTCATTCATCAGGCAGTAGAAGTAAATGCTCAAGATATTTATATCATTCCCAAAGG
TGATTGTTATGAACTCTATATGCGTATTGATGATGAAAGGCGGTTTATTGATGTTTTTGAGTTTAATAGGATGGCTAGTC
TTATTAGTCACTTTAAATTTGTGGCAGGCATGAACGTTGGAGAAAAAAGACGAAGTCAATTAGGTTCTTGTGACTATGAA
CTGTCAGAGGGAAGACTGGTTTCATTACGACTATCGAGTGTGGGAGATTATCGTGGTCAAGAATCTTTAGTTATTCGTAT
TTTGTATTCAGGTCATCAGGACTTAAAATATTGGTTTGATAATATAAAGCAAATGAAGGAAGTACTGGGTACAAGAGGGC
TATATCTTTTTTCCGGCCCTGTGGGGAGTGGTAAAACAACTCTCATGTATCAATTAGCTTCAGAAGTATTTAAAAATAAG
CAAATTATCACGATTGAAGATCCGGTAGAAATCAAGAATGACAAGATGTTACAACTCCAATTGAATGAGGATATTGGAAT
GACTTATGATGCTTTAATCAAACTGTCTTTACGGCATCGTCCAGATATTTTAATTATCGGAGAGATTAGAGATCAAGCGA
CGGCCCGTGCTGTTATTCGTGCAAGTTTAACGGGAGTGATGGTTTTTTCTACTATTCATGCTAAAAGTATTTCCGGAGTC
TATGATAGGCTTATAGAATTAGGGGTTAACTATCAAGAGTTAGAAAATAGTCTAAAATTAATAGCATATCAACGTTTAAT
TGGAGGAGGAAGCCTAATTGACTTTGAGACAGGTAACTTTAAAAAACACTCATCAGACAAGTGGAATAGACAAGTGGATA
TCTTGGCTGAAGAAGGACATATCAGTAAGAAACAGGCACAAGTCGAAAAAATTATCCCTCAAGAAACAACGGAAAGTAGT
CCAACTTTTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

68.489

96.285

0.659
  comYA Streptococcus mutans UA140

68.489

96.285

0.659
  comYA Streptococcus gordonii str. Challis substr. CH1

63.323

98.762

0.625
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

62.701

96.285

0.604
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

61.736

96.285

0.594
  comGA/cglA/cilD Streptococcus pneumoniae D39

61.736

96.285

0.594
  comGA/cglA/cilD Streptococcus pneumoniae R6

61.736

96.285

0.594
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

61.736

96.285

0.594
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

61.613

95.975

0.591
  comGA Lactococcus lactis subsp. cremoris KW2

50.621

99.69

0.505

Multiple sequence alignment