Detailed information
Bioinformatically predicted
Overview
| Name | comGC/cglC | Type | Machinery gene |
| Locus tag | GBS_RS01080 | Genome accession | NC_004368 |
| Coordinates | 189092..189421 (+) | Length | 109 a.a. |
| NCBI ID | WP_000793380.1 | Uniprot ID | A0A0E1EKJ1 |
| Organism | Streptococcus agalactiae NEM316 | ||
| Function | dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake |
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Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 190011..233191 | 189092..189421 | flank | 590 |
Gene organization within MGE regions
Location: 189092..233191
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| GBS_RS01080 (gbs0161) | comGC/cglC | 189092..189421 (+) | 330 | WP_000793380.1 | competence type IV pilus major pilin ComGC | Machinery gene |
| GBS_RS01085 (gbs0162) | comYD | 189396..189809 (+) | 414 | WP_000244259.1 | competence type IV pilus minor pilin ComGD | Machinery gene |
| GBS_RS01090 (gbs0163) | comGE | 189781..190080 (+) | 300 | WP_001867089.1 | competence type IV pilus minor pilin ComGE | - |
| GBS_RS01095 (gbs0164) | comGF | 190034..190495 (+) | 462 | WP_001874060.1 | competence type IV pilus minor pilin ComGF | - |
| GBS_RS01100 (gbs0165) | comGG | 190473..190844 (+) | 372 | WP_000601104.1 | competence type IV pilus minor pilin ComGG | - |
| GBS_RS01105 (gbs0166) | comYH | 190959..191933 (+) | 975 | WP_001008570.1 | class I SAM-dependent methyltransferase | Machinery gene |
| GBS_RS01110 (gbs0167) | - | 191965..193158 (+) | 1194 | WP_000047535.1 | acetate kinase | - |
| GBS_RS01115 (gbs0168) | - | 193309..193515 (+) | 207 | WP_000798242.1 | helix-turn-helix transcriptional regulator | - |
| GBS_RS11710 | - | 193574..193711 (+) | 138 | WP_001867090.1 | hypothetical protein | - |
| GBS_RS01120 (gbs0169) | - | 193752..194207 (+) | 456 | WP_000905674.1 | hypothetical protein | - |
| GBS_RS01125 (gbs0170) | - | 194276..194941 (+) | 666 | WP_000008111.1 | CPBP family intramembrane glutamic endopeptidase | - |
| GBS_RS01130 (gbs0171) | proC | 194962..195732 (-) | 771 | WP_001867096.1 | pyrroline-5-carboxylate reductase | - |
| GBS_RS01135 (gbs0172) | pepA | 195802..196869 (-) | 1068 | WP_001281321.1 | glutamyl aminopeptidase | - |
| GBS_RS01140 (gbs0173) | - | 197054..197293 (-) | 240 | WP_000660181.1 | hypothetical protein | - |
| GBS_RS01145 (gbs0174) | - | 197454..197738 (+) | 285 | WP_000791272.1 | DUF4651 domain-containing protein | - |
| GBS_RS01150 (gbs0175) | - | 197735..198058 (+) | 324 | WP_000601792.1 | thioredoxin family protein | - |
| GBS_RS01155 (gbs0176) | ytpR | 198091..198717 (+) | 627 | WP_000578331.1 | YtpR family tRNA-binding protein | - |
| GBS_RS01160 (gbs0177) | - | 198771..199487 (-) | 717 | WP_000186183.1 | class I SAM-dependent methyltransferase | - |
| GBS_RS01165 (gbs0178) | ssbA | 199568..199963 (+) | 396 | WP_000282450.1 | single-stranded DNA-binding protein | Machinery gene |
| GBS_RS01170 (gbs0179) | - | 200086..200730 (+) | 645 | WP_000416612.1 | HAD family phosphatase | - |
| GBS_RS01175 (gbs0180) | - | 200757..202502 (+) | 1746 | WP_000930334.1 | LytS/YhcK type 5TM receptor domain-containing protein | - |
| GBS_RS01180 (gbs0181) | - | 202483..203223 (+) | 741 | WP_000697630.1 | LytTR family DNA-binding domain-containing protein | - |
| GBS_RS01185 (gbs0182) | - | 203393..203848 (+) | 456 | WP_000683316.1 | CidA/LrgA family protein | - |
| GBS_RS01190 (gbs0183) | lrgB | 203850..204578 (+) | 729 | WP_000421727.1 | antiholin-like protein LrgB | - |
| GBS_RS01195 (gbs0184) | - | 204821..206449 (+) | 1629 | WP_000170504.1 | ABC transporter substrate-binding protein | - |
| GBS_RS01200 (gbs0185) | - | 206562..207539 (+) | 978 | WP_000680645.1 | ABC transporter permease | - |
| GBS_RS01205 (gbs0186) | - | 207536..208357 (+) | 822 | WP_000603397.1 | ABC transporter permease | - |
| GBS_RS01210 (gbs0187) | - | 208369..209172 (+) | 804 | WP_000140979.1 | ABC transporter ATP-binding protein | - |
| GBS_RS01215 (gbs0188) | - | 209156..209782 (+) | 627 | WP_000171304.1 | ABC transporter ATP-binding protein | - |
| GBS_RS01220 (gbs0189) | treP | 210064..212094 (+) | 2031 | WP_000434617.1 | PTS system trehalose-specific EIIBC component | - |
| GBS_RS01225 (gbs0190) | treC | 212316..213941 (+) | 1626 | WP_000151014.1 | alpha,alpha-phosphotrehalase | - |
| GBS_RS01230 (gbs0191) | - | 214161..216197 (+) | 2037 | WP_000228178.1 | BglG family transcription antiterminator | - |
| GBS_RS01235 (gbs0192) | - | 216200..216484 (+) | 285 | WP_000944235.1 | PTS sugar transporter subunit IIB | - |
| GBS_RS01240 (gbs0193) | - | 216497..217852 (+) | 1356 | WP_000677351.1 | PTS ascorbate transporter subunit IIC | - |
| GBS_RS01245 (gbs0194) | - | 217855..218712 (+) | 858 | WP_000203492.1 | transketolase | - |
| GBS_RS01250 (gbs0195) | - | 218709..219638 (+) | 930 | WP_001203827.1 | transketolase family protein | - |
| GBS_RS01255 (gbs0196) | - | 219747..221006 (+) | 1260 | WP_001203074.1 | ferric reductase-like transmembrane domain-containing protein | - |
| GBS_RS01260 | rpsO | 221094..221363 (+) | 270 | WP_001018249.1 | 30S ribosomal protein S15 | - |
| GBS_RS01265 (gbs0198) | pnp | 221744..223873 (+) | 2130 | WP_000043857.1 | polyribonucleotide nucleotidyltransferase | - |
| GBS_RS01270 (gbs0199) | - | 223875..224627 (+) | 753 | WP_000204784.1 | SseB family protein | - |
| GBS_RS01275 (gbs0200) | cysE | 224636..225220 (+) | 585 | WP_000539954.1 | serine O-acetyltransferase | - |
| GBS_RS01280 (gbs0201) | - | 225230..225412 (+) | 183 | WP_000656477.1 | hypothetical protein | - |
| GBS_RS01285 (gbs0202) | cysS | 225409..226752 (+) | 1344 | WP_000591129.1 | cysteine--tRNA ligase | - |
| GBS_RS01290 (gbs0203) | - | 226745..227131 (+) | 387 | WP_000568029.1 | Mini-ribonuclease 3 | - |
| GBS_RS01295 (gbs0204) | rlmB | 227234..227989 (+) | 756 | WP_000178019.1 | 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB | - |
| GBS_RS01300 (gbs0205) | - | 227986..228504 (+) | 519 | WP_000716637.1 | NYN domain-containing protein | - |
| GBS_RS01305 (gbs0206) | - | 228597..229457 (+) | 861 | WP_000143135.1 | DegV family protein | - |
| GBS_RS01310 (gbs0207) | - | 229995..230114 (+) | 120 | Protein_208 | helix-turn-helix transcriptional regulator | - |
| GBS_RS01315 (gbs0208) | - | 230442..231608 (-) | 1167 | WP_000160598.1 | IS30-like element ISSag9 family transposase | - |
| GBS_RS01320 (gbs0209) | rplM | 231909..232355 (+) | 447 | WP_001867156.1 | 50S ribosomal protein L13 | - |
| GBS_RS01325 (gbs0210) | rpsI | 232376..232768 (+) | 393 | WP_000035940.1 | 30S ribosomal protein S9 | - |
Sequence
Protein
Download Length: 109 a.a. Molecular weight: 12129.27 Da Isoelectric Point: 10.0311
>NTDB_id=22444 GBS_RS01080 WP_000793380.1 189092..189421(+) (comGC/cglC) [Streptococcus agalactiae NEM316]
MKNLLLKCKDKKVKAFTLLEMLVVLIIISVLLLLFVPNLSKQKESVTRTGNAAVVKVVESQAELFELQETGRKASLSTLK
SGGYITEKQEKAYLDYYKDSSNGSQKISS
MKNLLLKCKDKKVKAFTLLEMLVVLIIISVLLLLFVPNLSKQKESVTRTGNAAVVKVVESQAELFELQETGRKASLSTLK
SGGYITEKQEKAYLDYYKDSSNGSQKISS
Nucleotide
Download Length: 330 bp
>NTDB_id=22444 GBS_RS01080 WP_000793380.1 189092..189421(+) (comGC/cglC) [Streptococcus agalactiae NEM316]
ATGAAAAATTTATTGTTAAAATGTAAGGATAAGAAGGTTAAAGCATTTACACTTTTAGAAATGTTAGTTGTTTTGATCAT
TATTTCGGTCTTGTTGTTATTGTTTGTGCCCAATTTATCAAAACAAAAGGAAAGTGTCACAAGAACTGGAAATGCCGCTG
TTGTCAAGGTTGTAGAAAGTCAAGCCGAACTTTTTGAACTGCAAGAAACAGGTAGAAAAGCTAGTTTATCCACTCTAAAA
TCTGGAGGATATATTACTGAAAAGCAAGAAAAAGCCTATTTAGATTATTATAAAGACAGTTCCAATGGTTCTCAGAAAAT
TTCAAGTTAA
ATGAAAAATTTATTGTTAAAATGTAAGGATAAGAAGGTTAAAGCATTTACACTTTTAGAAATGTTAGTTGTTTTGATCAT
TATTTCGGTCTTGTTGTTATTGTTTGTGCCCAATTTATCAAAACAAAAGGAAAGTGTCACAAGAACTGGAAATGCCGCTG
TTGTCAAGGTTGTAGAAAGTCAAGCCGAACTTTTTGAACTGCAAGAAACAGGTAGAAAAGCTAGTTTATCCACTCTAAAA
TCTGGAGGATATATTACTGAAAAGCAAGAAAAAGCCTATTTAGATTATTATAAAGACAGTTCCAATGGTTCTCAGAAAAT
TTCAAGTTAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comGC/cglC | Streptococcus mitis NCTC 12261 |
60.55 |
100 |
0.606 |
| comGC/cglC | Streptococcus mitis SK321 |
59.633 |
100 |
0.596 |
| comYC | Streptococcus gordonii str. Challis substr. CH1 |
61.165 |
94.495 |
0.578 |
| comGC/cglC | Streptococcus pneumoniae TIGR4 |
57.798 |
100 |
0.578 |
| comGC/cglC | Streptococcus pneumoniae R6 |
57.798 |
100 |
0.578 |
| comGC/cglC | Streptococcus pneumoniae Rx1 |
57.798 |
100 |
0.578 |
| comGC/cglC | Streptococcus pneumoniae D39 |
57.798 |
100 |
0.578 |
| comYC | Streptococcus mutans UA159 |
55.238 |
96.33 |
0.532 |
| comYC | Streptococcus mutans UA140 |
55.238 |
96.33 |
0.532 |
| comGC | Lactococcus lactis subsp. cremoris KW2 |
63.043 |
84.404 |
0.532 |
| comYC | Streptococcus suis isolate S10 |
65.854 |
75.229 |
0.495 |