Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   A6J72_RS05945 Genome accession   NZ_CP020433
Coordinates   1195920..1197188 (+) Length   422 a.a.
NCBI ID   WP_009569648.1    Uniprot ID   -
Organism   Streptococcus intermedius strain FDAARGOS_233     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1190920..1202188
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J72_RS05915 (A6J72_05925) mutL 1191187..1193133 (+) 1947 WP_082311997.1 DNA mismatch repair endonuclease MutL -
  A6J72_RS05920 (A6J72_05930) - 1193279..1193788 (-) 510 WP_082311998.1 RDD family protein -
  A6J72_RS05925 (A6J72_05935) - 1193772..1194278 (-) 507 WP_082311999.1 helix-turn-helix domain-containing protein -
  A6J72_RS05930 (A6J72_05940) ruvA 1194448..1195041 (+) 594 WP_082312000.1 Holliday junction branch migration protein RuvA -
  A6J72_RS05935 (A6J72_05945) - 1195051..1195605 (+) 555 WP_082312001.1 DNA-3-methyladenine glycosylase I -
  A6J72_RS10035 (A6J72_05950) - 1195610..1195783 (+) 174 Protein_1144 CPBP family intramembrane glutamate endopeptidase -
  A6J72_RS05945 (A6J72_05955) cinA 1195920..1197188 (+) 1269 WP_009569648.1 competence/damage-inducible protein A Machinery gene
  A6J72_RS05950 (A6J72_05960) recA 1197237..1198382 (+) 1146 WP_003077215.1 recombinase RecA Machinery gene
  A6J72_RS05955 (A6J72_05965) spx 1198468..1198866 (+) 399 WP_003026638.1 transcriptional regulator Spx -
  A6J72_RS05960 (A6J72_05970) - 1199595..1200152 (+) 558 WP_082312002.1 SP0191 family lipoprotein -
  A6J72_RS05965 (A6J72_05975) - 1200458..1200724 (+) 267 WP_009569646.1 IreB family regulatory phosphoprotein -
  A6J72_RS05970 (A6J72_05980) ruvX 1200724..1201143 (+) 420 WP_003075276.1 Holliday junction resolvase RuvX -
  A6J72_RS05975 (A6J72_05985) - 1201161..1201466 (+) 306 WP_003075274.1 DUF1292 domain-containing protein -

Sequence

Protein


Download         Length: 422 a.a.        Molecular weight: 45595.15 Da        Isoelectric Point: 6.5191

>NTDB_id=223005 A6J72_RS05945 WP_009569648.1 1195920..1197188(+) (cinA) [Streptococcus intermedius strain FDAARGOS_233]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLASLGVDVYFQTVVGDNEDRLLSILEIARDRSNLVILTGGLGPTEDDLTKQT
LSKFLNRRLVFYQVAVEKLNRFFSSRPDYTRTPNNERQAQIVEGSTPLRNETGLAVGGVVEVSGVTYVVLPGPPSELKPM
VNNELVPLLATGQKLYSRVLRFFGIGESQLVTLLGNLIDTQTDPTIAPYAKTGEVTLRLSTKASSQKEADVKFAHLEKKI
LAVQTFEKQQLADLFYAYGDDNSLGQTAFELLKKAGKTVTAAESLTAGLFQATLANFSGASKVFGGGFVTYGIEEKSQML
GIPLADLEMHGVVSAYTAEKMATQARKLTASDYAVSLTGVAGPDSLEGHPAGTVYIGLATADNVQSIQVNIAGRSRTDVR
KIAVLHAFNLLRKTLLKNENML

Nucleotide


Download         Length: 1269 bp        

>NTDB_id=223005 A6J72_RS05945 WP_009569648.1 1195920..1197188(+) (cinA) [Streptococcus intermedius strain FDAARGOS_233]
ATGAAAGCAGAAATTATTGCTGTGGGTACTGAGATTTTGACTGGTCAGATTGTCAATACGAATGCTCAATTTTTATCTGA
AAAATTAGCGAGCTTGGGAGTAGATGTCTATTTCCAGACAGTGGTTGGAGATAATGAAGATCGTCTGTTATCCATTTTAG
AAATAGCTAGAGATCGTAGTAATTTAGTTATCTTGACAGGTGGTTTAGGTCCGACTGAAGACGACTTAACCAAGCAGACT
TTGTCAAAATTTTTGAATCGTAGGCTAGTCTTTTATCAAGTAGCTGTTGAAAAATTGAATCGTTTCTTCTCCAGCCGACC
AGACTATACTCGAACACCAAATAATGAGCGACAAGCTCAGATAGTAGAAGGGTCGACTCCTCTACGAAATGAAACCGGAC
TTGCAGTTGGTGGCGTTGTTGAAGTCAGTGGTGTGACTTATGTTGTTCTACCTGGCCCCCCTAGTGAACTAAAGCCTATG
GTAAACAATGAGTTGGTTCCGCTTTTAGCAACTGGCCAAAAATTGTATTCGAGAGTCTTGCGTTTCTTTGGTATTGGGGA
GAGTCAATTAGTCACCCTTTTAGGAAACTTGATTGATACTCAGACGGATCCGACCATTGCTCCTTATGCTAAGACGGGAG
AAGTGACGTTGCGATTGTCGACCAAGGCCAGCAGTCAAAAGGAAGCAGATGTTAAGTTTGCTCATCTGGAAAAGAAAATT
TTAGCAGTACAGACTTTTGAGAAACAACAATTAGCCGACCTTTTCTATGCTTATGGAGATGACAATTCTCTGGGACAGAC
AGCTTTTGAATTGTTGAAGAAAGCAGGCAAAACAGTCACAGCAGCTGAAAGTCTGACTGCGGGACTTTTTCAAGCGACTT
TAGCAAATTTTTCTGGAGCATCCAAGGTCTTTGGAGGTGGCTTTGTTACTTATGGCATAGAGGAGAAGAGTCAAATGTTA
GGCATTCCATTGGCAGATTTAGAAATGCATGGGGTAGTCTCAGCTTATACAGCAGAGAAAATGGCTACGCAAGCTAGGAA
ATTGACTGCTAGTGACTATGCGGTGAGTTTGACTGGAGTAGCAGGTCCAGATAGTTTAGAAGGCCATCCAGCAGGAACTG
TTTATATTGGCTTGGCAACTGCAGATAACGTTCAGTCTATTCAGGTTAATATTGCGGGGCGCAGTCGGACGGATGTACGT
AAAATAGCTGTGTTACATGCTTTCAATTTGTTGCGAAAAACTTTATTAAAAAATGAGAATATGCTATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Competence-damaged protein (CinA)

(263-415)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

74.88

99.052

0.742
  cinA Streptococcus pneumoniae TIGR4

73.445

99.052

0.727
  cinA Streptococcus mitis NCTC 12261

73.445

99.052

0.727
  cinA Streptococcus pneumoniae Rx1

73.206

99.052

0.725
  cinA Streptococcus pneumoniae R6

73.206

99.052

0.725
  cinA Streptococcus pneumoniae D39

72.967

99.052

0.723
  cinA Streptococcus mutans UA159

70.686

100

0.709
  cinA Streptococcus suis isolate S10

53.846

98.578

0.531
  cinA Bacillus subtilis subsp. subtilis str. 168

46.172

99.052

0.457

Multiple sequence alignment