Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   A6J68_RS02160 Genome accession   NZ_CP020432
Coordinates   386662..387633 (+) Length   323 a.a.
NCBI ID   WP_000250797.1    Uniprot ID   -
Organism   Streptococcus sp. 'group B' strain FDAARGOS_229     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 381662..392633
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J68_RS02145 (A6J68_02140) rpoC 382361..386011 (+) 3651 WP_000228729.1 DNA-directed RNA polymerase subunit beta' -
  A6J68_RS02150 (A6J68_02145) - 386125..386490 (+) 366 WP_000285373.1 DUF1033 family protein -
  A6J68_RS02160 (A6J68_02155) comYA 386662..387633 (+) 972 WP_000250797.1 competence type IV pilus ATPase ComGA Machinery gene
  A6J68_RS02165 (A6J68_02160) comYB 387527..388570 (+) 1044 WP_223297804.1 competence type IV pilus assembly protein ComGB Machinery gene
  A6J68_RS02170 (A6J68_02165) comGF 388595..389023 (+) 429 WP_223842274.1 competence type IV pilus minor pilin ComGF -
  A6J68_RS02175 (A6J68_02170) comGG 389001..389224 (+) 224 Protein_369 competence type IV pilus minor pilin ComGG -
  A6J68_RS02180 (A6J68_02175) comYH 389339..390313 (+) 975 WP_001008571.1 class I SAM-dependent methyltransferase Machinery gene
  A6J68_RS02185 (A6J68_02180) - 390345..391538 (+) 1194 WP_000047534.1 acetate kinase -
  A6J68_RS02190 (A6J68_02185) - 391689..391895 (+) 207 WP_000798241.1 helix-turn-helix transcriptional regulator -
  A6J68_RS02195 (A6J68_02190) - 391954..392091 (+) 138 WP_001869149.1 hypothetical protein -
  A6J68_RS02200 (A6J68_02195) - 392132..392587 (+) 456 WP_000905672.1 hypothetical protein -

Sequence

Protein


Download         Length: 323 a.a.        Molecular weight: 36866.33 Da        Isoelectric Point: 6.9110

>NTDB_id=222931 A6J68_RS02160 WP_000250797.1 386662..387633(+) (comYA) [Streptococcus sp. 'group B' strain FDAARGOS_229]
MVQSLAKHVIHQAVEVNAQDIYIIPKGDCYEFYMRIDDERRFIDVFEFNRMASLISHFKFVAGMNVGEKRRSQLGSCDYE
LSEGRLVSLRLSSVGDYRGQESLVIRTLYSGHQDLKYWFDNIKQMKEVLCARGLYLFSGPVGSGKTTLMYQLASEVFKNK
QIITIEDPVEIKNDKMLQLQLNEDIGMTYDALIKLSLRHRPDILIIGEIRDQATARAVIRASLTGVMVFSTIHAKSIPGV
YDRLIELGVNYQELENSLKLIAYQRLIGGGSLIDFETSNFKKHSSDKWNRQVDILAEEGHISKKQAQVEKIIPQETTESS
PTF

Nucleotide


Download         Length: 972 bp        

>NTDB_id=222931 A6J68_RS02160 WP_000250797.1 386662..387633(+) (comYA) [Streptococcus sp. 'group B' strain FDAARGOS_229]
ATGGTTCAATCATTAGCAAAGCACGTCATTCATCAGGCAGTAGAAGTAAATGCTCAAGATATTTATATCATTCCCAAAGG
TGATTGTTATGAATTCTATATGCGTATTGATGATGAAAGGCGGTTTATTGATGTTTTTGAGTTTAATAGGATGGCTAGTC
TTATTAGTCACTTTAAATTTGTGGCAGGCATGAACGTTGGAGAAAAAAGACGAAGTCAATTAGGTTCTTGTGACTATGAA
CTGTCAGAGGGAAGACTGGTTTCATTACGACTATCAAGTGTGGGAGATTATCGTGGTCAAGAATCTTTAGTTATTCGTAC
TTTGTATTCAGGTCATCAGGACTTAAAATATTGGTTTGATAATATAAAGCAAATGAAGGAAGTACTGTGTGCAAGAGGGC
TATATCTTTTTTCCGGCCCTGTGGGGAGTGGTAAAACAACTCTCATGTATCAATTAGCTTCAGAAGTATTTAAAAATAAG
CAAATTATCACGATTGAAGATCCGGTAGAAATCAAGAATGACAAGATGTTACAACTCCAATTGAATGAGGATATTGGAAT
GACTTATGATGCTTTAATCAAACTGTCTTTACGGCATCGTCCAGATATTTTAATTATCGGAGAGATTAGAGATCAAGCGA
CGGCCCGTGCTGTTATTCGTGCAAGTTTAACGGGAGTAATGGTTTTTTCTACTATTCATGCTAAAAGTATTCCCGGAGTC
TATGATAGGCTTATAGAATTAGGGGTTAACTATCAAGAGTTAGAAAATAGTCTAAAATTAATAGCATATCAACGTTTAAT
TGGAGGAGGAAGCCTAATTGACTTTGAGACAAGTAACTTTAAAAAACACTCATCAGACAAGTGGAATAGACAAGTGGATA
TCTTGGCTGAAGAAGGACATATCAGTAAGAAACAGGCACAAGTCGAAAAAATTATCCCTCAAGAAACAACGGAAAGTAGT
CCAACTTTTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

68.167

96.285

0.656
  comYA Streptococcus mutans UA140

68.167

96.285

0.656
  comYA Streptococcus gordonii str. Challis substr. CH1

63.323

98.762

0.625
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

62.379

96.285

0.601
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

61.935

95.975

0.594
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

61.415

96.285

0.591
  comGA/cglA/cilD Streptococcus pneumoniae D39

61.415

96.285

0.591
  comGA/cglA/cilD Streptococcus pneumoniae R6

61.415

96.285

0.591
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

61.415

96.285

0.591
  comGA Lactococcus lactis subsp. cremoris KW2

51.242

99.69

0.511

Multiple sequence alignment