Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   CXX08_RS05825 Genome accession   NZ_CP025869
Coordinates   1230036..1230668 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 503829     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1225036..1235668
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CXX08_RS05800 yhfG 1225168..1225335 (+) 168 WP_000736860.1 YhfG family protein -
  CXX08_RS05805 fic 1225325..1225927 (+) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  CXX08_RS05810 pabA 1225959..1226522 (+) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  CXX08_RS05815 argD 1226608..1227828 (+) 1221 WP_001297516.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  CXX08_RS05820 yhfK 1227895..1229985 (-) 2091 WP_001297515.1 YccS/YhfK family putative transporter -
  CXX08_RS05825 crp 1230036..1230668 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  CXX08_RS05830 yhfA 1230970..1231374 (+) 405 WP_001148908.1 OsmC family protein -
  CXX08_RS05835 prkB 1231429..1232298 (-) 870 WP_001274680.1 phosphoribulokinase -
  CXX08_RS05840 yheU 1232352..1232570 (-) 219 WP_000907085.1 YheU family protein -
  CXX08_RS05845 yheT 1232564..1233586 (-) 1023 WP_000057405.1 hydrolase -
  CXX08_RS05850 yheS 1233586..1235499 (-) 1914 WP_000634793.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=220666 CXX08_RS05825 WP_000242755.1 1230036..1230668(-) (crp) [Escherichia coli strain 503829]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=220666 CXX08_RS05825 WP_000242755.1 1230036..1230668(-) (crp) [Escherichia coli strain 503829]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment