Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   AZI11_RS04755 Genome accession   NZ_CP019734
Coordinates   987724..988974 (+) Length   416 a.a.
NCBI ID   WP_039105136.1    Uniprot ID   A0A0C1PXC1
Organism   Levilactobacillus brevis strain TMW 1.2108     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 982724..993974
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AZI11_RS04735 (AZI11_04740) yfmF 983438..984733 (+) 1296 WP_039105134.1 EF-P 5-aminopentanol modification-associated protein YfmF -
  AZI11_RS04740 (AZI11_04745) yfmH 984711..986000 (+) 1290 WP_021742877.1 EF-P 5-aminopentanol modification-associated protein YfmH -
  AZI11_RS04745 (AZI11_04750) - 986114..986968 (+) 855 WP_085768889.1 helix-turn-helix domain-containing protein -
  AZI11_RS04750 (AZI11_04755) pgsA 987081..987668 (+) 588 WP_011668109.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  AZI11_RS04755 (AZI11_04760) cinA 987724..988974 (+) 1251 WP_039105136.1 competence/damage-inducible protein A Machinery gene
  AZI11_RS04760 (AZI11_04765) recA 989068..990201 (+) 1134 WP_085768890.1 recombinase RecA Machinery gene
  AZI11_RS14965 - 990284..990436 (-) 153 WP_164475119.1 hypothetical protein -
  AZI11_RS04765 (AZI11_04770) rny 990764..992323 (+) 1560 WP_085768891.1 ribonuclease Y -
  AZI11_RS04770 (AZI11_04775) - 992455..993249 (+) 795 WP_085768892.1 TIGR00282 family metallophosphoesterase -

Sequence

Protein


Download         Length: 416 a.a.        Molecular weight: 44787.89 Da        Isoelectric Point: 5.4819

>NTDB_id=218208 AZI11_RS04755 WP_039105136.1 987724..988974(+) (cinA) [Levilactobacillus brevis strain TMW 1.2108]
MQAEIIAVGTEILLGQIVDTNSAFIARELAEAGIEVYYHSLVGDNATRLTAVVEQARSRSDLVIISGGLGPTKDDLTKQT
VAHLLGVKLVEDALAMAKIRRRFAINGREMTPNNRLQALYPAGSQPLANRTGLAVGAFYQDPDGADIMLLPGPPSETEPM
FREQALPLLKQTYPRSEYLSSRVLRFFGIGESQLVTQLSDLIDQQTNPTIAPYAKVNEVTLRLTAQAPDEMQGQRLLDDL
TATIKARVGDYLYGYGDDNSLAAVVVQTLIDRQLTITAAESLTAGQFQSTLGSVPGVSAVFPGGFVTYAASAKHDLLGVS
QATIDHDGVVSAATAKEMASRSRERLDTDFSLSFTGVAGPDALEGQPAGTVWLGLAQRGQQPQAKLLHLTGTRSAIRERS
VLTGLDWLRRTLQKVK

Nucleotide


Download         Length: 1251 bp        

>NTDB_id=218208 AZI11_RS04755 WP_039105136.1 987724..988974(+) (cinA) [Levilactobacillus brevis strain TMW 1.2108]
GTGCAAGCAGAAATTATTGCGGTTGGTACAGAGATTTTACTCGGGCAAATTGTGGATACGAACTCTGCCTTCATTGCGCG
CGAACTGGCGGAAGCTGGGATTGAGGTGTATTACCATTCTCTAGTAGGTGATAACGCAACCCGGTTAACGGCTGTTGTTG
AACAAGCCCGTTCGCGGAGTGATTTAGTGATTATTAGTGGGGGATTAGGACCGACCAAAGATGATTTGACAAAACAAACG
GTCGCTCACTTGTTAGGCGTAAAGTTGGTTGAAGATGCGTTGGCAATGGCTAAGATTCGTCGCCGGTTTGCTATCAATGG
CCGTGAGATGACGCCTAATAATCGCCTACAAGCTTTATATCCAGCAGGCAGTCAGCCCTTAGCAAATCGGACTGGGTTAG
CTGTGGGAGCTTTTTATCAAGATCCTGATGGTGCGGACATCATGCTATTACCGGGACCACCAAGTGAGACTGAACCCATG
TTTCGTGAGCAAGCCTTACCCCTGCTGAAGCAAACATATCCACGAAGTGAGTACTTGTCTTCACGGGTACTTCGGTTCTT
TGGCATCGGCGAAAGTCAATTGGTCACTCAACTGAGTGATCTGATTGACCAGCAGACTAATCCGACCATCGCTCCTTATG
CTAAAGTTAATGAAGTAACGTTACGTTTAACCGCACAGGCCCCGGATGAGATGCAAGGGCAACGCCTCTTAGATGACTTA
ACGGCGACGATTAAGGCCCGCGTAGGGGATTATCTTTATGGTTATGGTGATGATAATTCATTGGCGGCAGTGGTGGTTCA
GACACTAATTGACCGTCAATTGACCATTACGGCTGCTGAGAGCTTAACGGCCGGTCAATTTCAAAGTACCTTGGGAAGTG
TTCCCGGTGTTTCGGCGGTTTTCCCTGGTGGTTTTGTCACCTATGCGGCCAGTGCCAAGCATGACTTATTGGGAGTCTCG
CAGGCCACGATTGATCATGATGGTGTGGTTAGTGCGGCGACAGCTAAGGAAATGGCATCACGTTCTCGAGAACGGTTGGA
CACTGATTTTTCGTTGAGCTTCACAGGAGTTGCTGGCCCGGACGCCTTGGAAGGCCAACCGGCTGGAACAGTCTGGTTAG
GTTTAGCGCAACGGGGGCAACAACCACAGGCAAAACTGTTACATTTGACGGGTACGCGATCGGCAATTCGGGAACGGAGT
GTCTTGACCGGGTTGGACTGGTTGCGACGAACATTGCAAAAAGTAAAATAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(259-412)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Damage-inducible protein CinA KH domain (CinA_KH)

(181-254)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0C1PXC1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

51.566

99.76

0.514
  cinA Streptococcus mitis NCTC 12261

49.644

100

0.502
  cinA Streptococcus mitis SK321

49.762

100

0.502
  cinA Streptococcus pneumoniae TIGR4

48.694

100

0.493
  cinA Streptococcus pneumoniae Rx1

48.694

100

0.493
  cinA Streptococcus pneumoniae R6

48.694

100

0.493
  cinA Streptococcus pneumoniae D39

48.456

100

0.49
  cinA Bacillus subtilis subsp. subtilis str. 168

47.7

99.279

0.474
  cinA Streptococcus suis isolate S10

44.231

100

0.442

Multiple sequence alignment