Detailed information NTG0216315

Bioinformatically predicted

Overview

• Name: comEA/celA/cilE
• Type: Machinery gene
• Locus tag: BWR56_RS03625
• Genome accession: NZ_CP019562
• Coordinates: 751490..752140 (+)
• Length: 216 a.a.
• NCBI ID: WP_076984480.1
• Uniprot ID: -
• Organism: Streptococcus oralis strain S.MIT/ORALIS-351
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 746490..757140

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BWR56_RS03590 (BWR56_0708)	cvfB	746763..747617 (+)	855	WP_009730017.1	RNA-binding virulence regulatory protein CvfB	-
BWR56_RS03595 (BWR56_0709)	-	747629..748234 (+)	606	WP_042902395.1	GrpB family protein	-
BWR56_RS03600 (BWR56_0710)	-	748231..748446 (+)	216	WP_001232084.1	YozE family protein	-
BWR56_RS03605 (BWR56_0711)	-	748527..749513 (+)	987	WP_076984477.1	PhoH family protein	-
BWR56_RS03610 (BWR56_0712)	ald	749564..750676 (-)	1113	WP_076984478.1	alanine dehydrogenase	-
BWR56_RS03620 (BWR56_0713)	-	750853..751422 (+)	570	WP_076984479.1	GNAT family N-acetyltransferase	-
BWR56_RS03625 (BWR56_0714)	comEA/celA/cilE	751490..752140 (+)	651	WP_076984480.1	helix-hairpin-helix domain-containing protein	Machinery gene
BWR56_RS03630 (BWR56_0715)	comEC/celB	752124..754364 (+)	2241	WP_076984481.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
BWR56_RS03635 (BWR56_0716)	infC	754584..755114 (+)	531	WP_000848184.1	translation initiation factor IF-3	-
BWR56_RS03640 (BWR56_0717)	rpmI	755147..755347 (+)	201	WP_001125942.1	50S ribosomal protein L35	-
BWR56_RS03645 (BWR56_0718)	rplT	755399..755758 (+)	360	WP_000124830.1	50S ribosomal protein L20	-

Sequence

Protein

• Length: 216 a.a.
• Molecular weight: 23210.47 Da
• Isoelectric Point: 6.5116

>NTDB_id=216315 BWR56_RS03625 WP_076984480.1 751490..752140(+) (comEA/celA/cilE) [Streptococcus oralis strain S.MIT/ORALIS-351]
MEAIIEKIKEYKIIVICAILGLALGGFFLLKPTSQTPVKEKNLQAEVSAVSKDSSSEKEVKKEEKEESAEQDLITVDVKG
AVKSPGIYDLPVGSRVHDAVQKAGGLTEEADSKSLNLAQKVSDEALVYVPTKGEEAASQQAASGTTPSTSKEKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGAKTIEKLKDYVTVD

Nucleotide

• Length: 651 bp

>NTDB_id=216315 BWR56_RS03625 WP_076984480.1 751490..752140(+) (comEA/celA/cilE) [Streptococcus oralis strain S.MIT/ORALIS-351]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATTGTCATTTGTGCTATTTTAGGTTTGGCCTTGGGCGGATT
TTTCCTACTAAAGCCAACTTCACAAACACCCGTCAAAGAAAAGAATTTGCAAGCTGAAGTCTCGGCCGTTTCAAAGGATT
CATCGTCTGAAAAGGAAGTCAAGAAGGAAGAAAAGGAAGAGTCTGCTGAACAAGATCTGATCACAGTGGATGTCAAAGGT
GCTGTTAAATCGCCAGGGATTTATGATTTACCAGTAGGGAGTCGTGTTCATGATGCTGTTCAGAAAGCTGGTGGATTGAC
AGAGGAAGCAGATAGTAAGTCGCTTAATCTCGCTCAGAAAGTCAGTGACGAGGCTCTTGTCTATGTTCCAACTAAGGGAG
AAGAAGCGGCTAGTCAGCAGGCTGCCTCTGGAACGACTCCTTCGACAAGTAAAGAAAAGAAGGTCAATCTCAATAAAGCT
AGTCTGGAAGAACTAAAGCAGGTCAAAGGCTTGGGAGGAAAACGAGCTCAGGATATTATCGACCATCGTGAGGCAAATGG
CAAATTCAAGTCGGTAGATGAATTAAAGAAGGTCTCTGGCATTGGCGCTAAGACCATAGAAAAGCTAAAAGATTATGTCA
CAGTGGATTAA

Domains

Predicted by InterproScan.

• SLBB domain (SLBB) (76-126)

• Helix-hairpin-helix motif (HHH_3) (151-214)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA/celA/cilE	Streptococcus mitis NCTC 12261	92.13	100	0.921
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	91.204	100	0.912
comEA/celA/cilE	Streptococcus pneumoniae Rx1	89.352	100	0.894
comEA/celA/cilE	Streptococcus pneumoniae D39	89.352	100	0.894
comEA/celA/cilE	Streptococcus pneumoniae R6	89.352	100	0.894
comEA/celA/cilE	Streptococcus mitis SK321	87.5	100	0.875
comEA	Lactococcus lactis subsp. cremoris KW2	41.441	100	0.426
comEA	Streptococcus thermophilus LMD-9	39.524	97.222	0.384
comEA	Latilactobacillus sakei subsp. sakei 23K	33.906	100	0.366
comEA	Bacillus subtilis subsp. subtilis str. 168	39.109	93.519	0.366