Detailed information NTG0216316

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: BWR56_RS03630
• Genome accession: NZ_CP019562
• Coordinates: 752124..754364 (+)
• Length: 746 a.a.
• NCBI ID: WP_076984481.1
• Uniprot ID: -
• Organism: Streptococcus oralis strain S.MIT/ORALIS-351
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 747124..759364

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BWR56_RS03595 (BWR56_0709)	-	747629..748234 (+)	606	WP_042902395.1	GrpB family protein	-
BWR56_RS03600 (BWR56_0710)	-	748231..748446 (+)	216	WP_001232084.1	YozE family protein	-
BWR56_RS03605 (BWR56_0711)	-	748527..749513 (+)	987	WP_076984477.1	PhoH family protein	-
BWR56_RS03610 (BWR56_0712)	ald	749564..750676 (-)	1113	WP_076984478.1	alanine dehydrogenase	-
BWR56_RS03620 (BWR56_0713)	-	750853..751422 (+)	570	WP_076984479.1	GNAT family N-acetyltransferase	-
BWR56_RS03625 (BWR56_0714)	comEA/celA/cilE	751490..752140 (+)	651	WP_076984480.1	helix-hairpin-helix domain-containing protein	Machinery gene
BWR56_RS03630 (BWR56_0715)	comEC/celB	752124..754364 (+)	2241	WP_076984481.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
BWR56_RS03635 (BWR56_0716)	infC	754584..755114 (+)	531	WP_000848184.1	translation initiation factor IF-3	-
BWR56_RS03640 (BWR56_0717)	rpmI	755147..755347 (+)	201	WP_001125942.1	50S ribosomal protein L35	-
BWR56_RS03645 (BWR56_0718)	rplT	755399..755758 (+)	360	WP_000124830.1	50S ribosomal protein L20	-
BWR56_RS03650 (BWR56_0719)	-	755934..757598 (+)	1665	WP_076984482.1	molecular chaperone HscC	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84743.76 Da
• Isoelectric Point: 8.4773

>NTDB_id=216316 BWR56_RS03630 WP_076984481.1 752124..754364(+) (comEC/celB) [Streptococcus oralis strain S.MIT/ORALIS-351]
MSQWIKNFPIPLIYLSFLLLWLYYAIFGVSYLALLGFVFLLFCLFFQFPWKSAGKVLAICGVFGFWFLFQNWQQTQASQN
LVDSVERVRILPDTIKVNGDSLSFRGKADGRTFQVYYKLQSEEEKELFQALTDLHEIELEGKVSDPEGQRNFGGFDYQAY
LKTQGIYQTLTIKSIQSLKQVSSWNIGENLSSLRRKAVVWIKMHFPDPMRNYMTGLLFGHLDTDFEEMNELYSSLGIIHL
FALSGMQVGFFMDAFKKLLLRLGLTQEKLKWLTYPFSLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFII
MPNFFLTAGGVLSCAYAFILTMTSKEDDGLKAVAGESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDVVFLPLLSI
LFILSFIYPVTQFNFVFEWLENIIRLVSQLASRPLVFGQPNAWLLILLLVSLALVYDMRKNIKRLAGFSLFIVGLFFLTK
HPLENEITMLDVGQGESIFLRDMTGKTILIDVGGKAESDKKIEAWQEKSTTSNAQRTLIPYLKSRGVDKIDQLILTNTDK
EHIGDLLEVTKAFHVGEILVSKGSLTQKEFVSELEASQTKVRSVTAGENLPIFGSYLELLSPRQIGDGDRDGSLILYGKL
LDKHFLFTGNLKEKGEKDLLKQYPDLEVDVLKAGQHGAKTSSNSAFLEQLKPEFTLISVGKNNRAKLPHQETLTRLESIK
SKIYRTDQQGAIRFKGWNSWRIETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=216316 BWR56_RS03630 WP_076984481.1 752124..754364(+) (comEC/celB) [Streptococcus oralis strain S.MIT/ORALIS-351]
ATGTCACAGTGGATTAAGAATTTCCCTATCCCCCTAATCTATCTGAGCTTTCTGTTACTCTGGCTTTACTATGCCATTTT
TGGAGTGTCCTATCTCGCACTGCTAGGTTTTGTTTTTTTGCTCTTCTGCCTCTTTTTCCAATTTCCATGGAAATCTGCTG
GAAAAGTTTTAGCGATTTGTGGAGTTTTTGGATTTTGGTTTTTGTTTCAAAATTGGCAACAGACACAAGCAAGTCAAAAC
CTAGTAGATTCTGTTGAAAGGGTACGGATTTTGCCTGACACTATTAAGGTCAATGGAGACAGTCTGTCCTTTCGGGGCAA
GGCTGACGGCCGTACCTTCCAAGTTTACTATAAACTCCAGTCTGAGGAGGAAAAAGAGCTCTTTCAAGCCTTAACAGATC
TTCACGAGATAGAGCTAGAAGGGAAAGTTTCAGATCCTGAAGGGCAGAGAAATTTTGGTGGATTTGACTACCAAGCCTAT
CTAAAGACCCAGGGGATTTATCAGACACTGACTATCAAGAGCATCCAGTCACTTAAACAGGTTAGCAGTTGGAATATAGG
AGAAAATCTGTCCAGTTTACGTCGAAAGGCTGTAGTTTGGATTAAGATGCACTTTCCAGATCCTATGCGCAACTATATGA
CAGGTCTTCTTTTCGGACATCTAGATACTGATTTTGAGGAGATGAATGAGCTCTATTCCAGTCTTGGAATTATCCATCTC
TTTGCTCTGTCGGGTATGCAGGTGGGTTTCTTTATGGATGCCTTTAAGAAACTCCTCTTGCGATTGGGCTTGACCCAAGA
GAAGTTGAAGTGGCTAACTTATCCCTTTTCTCTTATCTATGCAGGTCTGACAGGATTTTCAGCATCTGTTATTCGCAGTC
TCTTGCAAAAGTTACTAGCCCAACATGGTGTTAAGGGTTTGGATAATTTTGCCCTAACGGTCCTTGTCCTCTTTATCATC
ATGCCTAACTTTTTCCTAACTGCAGGAGGGGTCTTATCCTGCGCTTACGCTTTTATCTTGACCATGACTAGTAAAGAAGA
CGATGGGCTCAAGGCTGTTGCTGGAGAAAGTCTGGTCATTTCCTTGGGAATATTGCCCATTTTATCCTTTTATTTTGCAG
AATTTCAGCCTTGGTCTATTCTTTTGACCTTTGTCTTTTCCTTTCTGTTTGATGTGGTCTTCTTACCGCTTTTGTCCATC
TTATTCATTCTGTCTTTTATTTACCCAGTCACTCAGTTTAACTTTGTCTTTGAGTGGTTGGAGAACATCATTCGCTTGGT
ATCGCAGCTGGCAAGTAGGCCCCTGGTCTTTGGTCAACCCAACGCATGGCTGTTGATTCTACTGTTAGTTTCATTAGCCT
TAGTCTATGACATGAGGAAAAACATTAAAAGACTAGCAGGATTTAGTCTCTTTATTGTGGGTCTCTTTTTCCTGACCAAG
CATCCGCTGGAAAATGAAATCACTATGTTGGATGTGGGGCAAGGAGAAAGTATTTTCCTACGGGATATGACTGGTAAAAC
TATTCTCATAGATGTAGGTGGTAAGGCAGAATCTGATAAGAAAATCGAGGCTTGGCAAGAAAAGTCGACGACCAGCAATG
CCCAGCGTACCTTGATTCCCTATCTAAAAAGTCGAGGAGTAGACAAGATTGACCAGCTGATTTTGACAAATACAGATAAG
GAGCATATTGGCGATTTGCTGGAGGTGACCAAGGCTTTCCATGTCGGGGAGATTTTAGTATCAAAAGGAAGTTTGACACA
GAAGGAATTTGTATCAGAACTAGAAGCAAGCCAAACCAAGGTACGCAGTGTGACAGCAGGGGAAAACTTGCCGATTTTTG
GCAGTTACTTAGAACTTCTATCTCCAAGGCAGATTGGAGATGGGGATCGTGATGGTTCCCTGATTCTTTATGGGAAACTT
TTGGATAAGCACTTTCTCTTCACAGGAAATTTGAAAGAGAAGGGAGAGAAGGATCTTCTAAAGCAATACCCTGACTTAGA
GGTGGATGTCCTGAAAGCAGGTCAACATGGTGCTAAAACATCATCCAATTCAGCTTTCCTAGAACAGCTCAAACCGGAGT
TCACTCTCATCTCAGTTGGAAAAAACAATCGTGCGAAACTCCCCCATCAGGAAACCTTGACACGACTGGAAAGTATCAAG
AGTAAGATTTACCGAACTGACCAGCAAGGGGCTATTCGCTTTAAAGGATGGAATAGTTGGCGAATTGAAACGGTTCGATA
A

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-637)

• Competence protein (Competence) (216-458)

• Domain of unknown function (DUF4131) (DUF4131) (29-177)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	88.472	100	0.885
comEC/celB	Streptococcus mitis NCTC 12261	88.188	99.866	0.881
comEC/celB	Streptococcus pneumoniae TIGR4	86.327	100	0.863
comEC/celB	Streptococcus pneumoniae Rx1	85.925	100	0.859
comEC/celB	Streptococcus pneumoniae D39	85.925	100	0.859
comEC/celB	Streptococcus pneumoniae R6	85.925	100	0.859
comEC	Lactococcus lactis subsp. cremoris KW2	44.818	99.598	0.446