Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   BWR56_RS01275 Genome accession   NZ_CP019562
Coordinates   249682..250938 (+) Length   418 a.a.
NCBI ID   WP_049505415.1    Uniprot ID   A0A139Q522
Organism   Streptococcus oralis strain S.MIT/ORALIS-351     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 244682..255938
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BWR56_RS01250 (BWR56_0243) ndk 246350..246769 (+) 420 WP_076984297.1 nucleoside-diphosphate kinase -
  BWR56_RS01255 (BWR56_0244) comM 246904..247527 (+) 624 WP_076984885.1 hypothetical protein Regulator
  BWR56_RS01260 (BWR56_0245) tsaE 247611..248054 (+) 444 WP_049505418.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  BWR56_RS01265 (BWR56_0246) - 248044..248565 (+) 522 WP_049505417.1 GNAT family N-acetyltransferase -
  BWR56_RS01270 (BWR56_0247) brpA 248570..249610 (+) 1041 WP_049505416.1 biofilm formation/cell division transcriptional regulator BrpA -
  BWR56_RS01275 (BWR56_0248) cinA 249682..250938 (+) 1257 WP_049505415.1 competence/damage-inducible protein A Machinery gene
  BWR56_RS01280 (BWR56_0249) recA 250993..252141 (+) 1149 WP_001085515.1 recombinase RecA Machinery gene
  BWR56_RS01285 (BWR56_0250) - 252191..252745 (-) 555 WP_049505414.1 GNAT family N-acetyltransferase -
  BWR56_RS01290 (BWR56_0251) - 252846..254216 (+) 1371 WP_049505413.1 MATE family efflux transporter -
  BWR56_RS01295 (BWR56_0252) - 254313..255029 (+) 717 WP_000532894.1 YebC/PmpR family DNA-binding transcriptional regulator -
  BWR56_RS01300 (BWR56_0253) - 255079..255783 (-) 705 WP_076984298.1 CD20-like domain-containing protein -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45176.50 Da        Isoelectric Point: 4.9883

>NTDB_id=216300 BWR56_RS01275 WP_049505415.1 249682..250938(+) (cinA) [Streptococcus oralis strain S.MIT/ORALIS-351]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGDNEARLLSLLEIASLRSSLVILTGGLGPTEDDLTKQT
LAKFLGKNLVFDPQAQEKLDIFFAHRPDYARTPNNERQAQIVEGATPLPNETGLAVGGVSEVDGVTYVVLPGPPNELKPM
VLNQLLPKLMTGAKLYSRVLRFFGIGESQLVTILADLIDQQTDPTLAPYAKTGEVTLRLSTKAVSQEKADQALDILENQI
LNRQTFEGHSLRDICYGYGEETSLASVVVEELKKRQKSITAAESLTAGLFQATLADFSGVSAVFNGGFVTYSLEEKSKML
DISEQELKEHGVVSEFTARKMAEQARFKTQSDYGVSLTGVAGPDSIEGHPAGTVFIGLAHAKGTEVIKANIAGRSRADVR
HIAVMHAFNLVRKALLSD

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=216300 BWR56_RS01275 WP_049505415.1 249682..250938(+) (cinA) [Streptococcus oralis strain S.MIT/ORALIS-351]
ATGAAAGCAGAAATTATTGCTGTAGGAACGGAAATTTTGACAGGGCAGATTGTCAATACCAATGCTCAGTTTTTATCAGA
GAAACTAGCCGAAATCGGGGTAGACGTCTACTTCCAAACAGCTGTTGGGGATAATGAAGCTCGTCTTTTGTCCTTGCTTG
AGATTGCGAGTTTGCGTAGCAGTTTAGTCATTTTGACAGGAGGCTTGGGACCAACTGAGGATGATTTGACCAAACAAACG
TTGGCAAAATTTTTGGGAAAAAATCTAGTGTTTGATCCTCAAGCACAAGAGAAATTGGATATTTTCTTTGCTCATAGACC
TGACTATGCTCGTACACCGAATAATGAGCGCCAAGCCCAAATTGTGGAAGGGGCAACTCCATTGCCAAATGAGACAGGCT
TAGCAGTAGGAGGGGTGTCAGAAGTGGATGGTGTGACCTACGTGGTCCTCCCAGGACCACCTAATGAATTGAAACCCATG
GTCTTAAACCAACTCTTACCCAAGTTAATGACTGGTGCTAAGCTCTATTCACGAGTGCTTCGTTTCTTTGGGATTGGGGA
GAGCCAGTTGGTGACTATTTTGGCGGACTTGATTGACCAGCAAACGGATCCGACCTTGGCTCCTTATGCCAAAACGGGAG
AGGTGACCTTGCGCTTGTCTACAAAAGCAGTCAGTCAAGAAAAGGCTGATCAAGCCTTGGACATCTTGGAGAACCAAATT
TTGAATCGCCAGACTTTCGAGGGACATTCACTGAGAGATATCTGTTATGGATATGGAGAAGAAACCAGCCTAGCAAGTGT
CGTTGTAGAAGAACTTAAGAAGAGACAGAAAAGCATTACTGCAGCAGAGAGTTTGACGGCAGGCCTCTTTCAGGCTACTT
TAGCAGACTTTTCAGGTGTTTCAGCTGTCTTTAATGGAGGGTTTGTCACCTACAGCCTAGAGGAAAAGTCCAAGATGCTG
GATATTTCCGAGCAAGAACTGAAAGAACACGGGGTCGTTTCAGAGTTTACCGCTCGAAAAATGGCAGAGCAGGCACGGTT
CAAGACTCAGTCTGACTACGGAGTTAGTTTGACGGGTGTGGCAGGACCAGATAGCATAGAGGGGCATCCAGCTGGAACCG
TCTTTATCGGCTTGGCACATGCAAAAGGAACAGAAGTTATCAAGGCGAATATCGCAGGACGGAGCCGTGCAGATGTTCGT
CATATTGCGGTAATGCATGCCTTTAACCTAGTTCGCAAGGCTTTATTAAGTGACTAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-243)

Competence-damaged protein (CinA)

(262-414)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A139Q522

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

89.474

100

0.895
  cinA Streptococcus pneumoniae TIGR4

88.756

100

0.888
  cinA Streptococcus pneumoniae Rx1

88.756

100

0.888
  cinA Streptococcus pneumoniae R6

88.756

100

0.888
  cinA Streptococcus mitis NCTC 12261

88.517

100

0.885
  cinA Streptococcus pneumoniae D39

88.517

100

0.885
  cinA Streptococcus mutans UA159

69.856

100

0.699
  cinA Streptococcus suis isolate S10

54.808

99.522

0.545
  cinA Bacillus subtilis subsp. subtilis str. 168

45.215

100

0.452

Multiple sequence alignment