Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   BZG42_RS06495 Genome accession   NZ_CP019557
Coordinates   1376433..1377089 (-) Length   218 a.a.
NCBI ID   WP_024532637.1    Uniprot ID   -
Organism   Streptococcus sp. DAT741     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1371433..1382089
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BZG42_RS06475 (BZG42_06550) sodA 1371463..1372074 (-) 612 WP_024532641.1 superoxide dismutase SodA -
  BZG42_RS06480 (BZG42_06555) holA 1372171..1373202 (-) 1032 WP_120172488.1 DNA polymerase III subunit delta -
  BZG42_RS06485 (BZG42_06560) - 1373458..1374069 (-) 612 WP_155995984.1 hypothetical protein -
  BZG42_RS06490 (BZG42_06565) comEC/celB 1374215..1376449 (-) 2235 WP_155995986.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  BZG42_RS06495 (BZG42_06570) comEA 1376433..1377089 (-) 657 WP_024532637.1 helix-hairpin-helix domain-containing protein Machinery gene
  BZG42_RS06500 (BZG42_06575) - 1377174..1377917 (-) 744 WP_024532636.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  BZG42_RS06505 (BZG42_06580) - 1378107..1379552 (+) 1446 WP_155995988.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  BZG42_RS06510 (BZG42_06585) - 1379911..1380699 (+) 789 WP_155995990.1 ABC transporter ATP-binding protein -
  BZG42_RS06515 (BZG42_06590) - 1380709..1381638 (+) 930 WP_120171917.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23008.77 Da        Isoelectric Point: 4.4459

>NTDB_id=216227 BZG42_RS06495 WP_024532637.1 1376433..1377089(-) (comEA) [Streptococcus sp. DAT741]
MEKVIECIKEYKWQVGLPVIAVVVVASFLLFRQSAQPVDQTGLTKFSQTEQISSSQEVIEETSTEASEKNSKLVVDVKGA
VINPGLYTLETGARINDAIAAAGGFTSQADQKSINLAQKLTDETVVYVASQGENISVVPNSSTSSALSQEGNKSGLVNLN
TATVADLQTISGIGAKRAADIIAYREANGSFKSVDDLSNVSGIGDKTLESIRSYVTVG

Nucleotide


Download         Length: 657 bp        

>NTDB_id=216227 BZG42_RS06495 WP_024532637.1 1376433..1377089(-) (comEA) [Streptococcus sp. DAT741]
ATGGAAAAAGTTATTGAATGCATTAAAGAATACAAGTGGCAAGTTGGTCTGCCTGTGATAGCAGTAGTGGTGGTGGCGAG
TTTTCTTCTTTTTAGACAGTCAGCTCAGCCAGTTGACCAGACAGGATTGACCAAGTTTTCACAGACAGAACAAATCAGCT
CCAGTCAAGAAGTGATAGAAGAGACCTCGACAGAAGCTAGCGAGAAAAACAGCAAACTAGTGGTGGATGTCAAGGGTGCA
GTGATAAATCCCGGTCTTTACACCTTAGAGACTGGTGCCCGTATCAATGATGCTATTGCCGCAGCGGGCGGTTTCACTAG
TCAAGCAGATCAAAAATCTATCAATCTAGCACAAAAGCTGACTGATGAAACAGTCGTCTATGTGGCTAGTCAGGGTGAGA
ATATTTCGGTAGTTCCCAATTCTTCAACTAGCTCAGCCCTGTCTCAAGAGGGAAATAAATCTGGTCTAGTTAATCTGAAT
ACAGCTACGGTGGCGGACTTACAGACCATTTCAGGCATCGGTGCTAAGCGAGCAGCGGATATTATTGCTTATCGTGAAGC
CAATGGTTCCTTCAAGTCGGTGGACGATCTCAGCAATGTTTCTGGCATTGGTGACAAGACCCTAGAAAGTATCCGCTCCT
ATGTTACGGTTGGATAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(74-128)

Helix-hairpin-helix motif (HHH_3)

(155-216)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Streptococcus thermophilus LMD-9

47.807

100

0.5
  comEA/celA/cilE Streptococcus pneumoniae Rx1

46.637

100

0.477
  comEA/celA/cilE Streptococcus pneumoniae D39

46.637

100

0.477
  comEA/celA/cilE Streptococcus pneumoniae R6

46.637

100

0.477
  comEA/celA/cilE Streptococcus mitis NCTC 12261

46.637

100

0.477
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

46.119

100

0.463
  comEA/celA/cilE Streptococcus mitis SK321

44.495

100

0.445
  comEA Lactococcus lactis subsp. cremoris KW2

41.441

100

0.422
  comEA Bacillus subtilis subsp. subtilis str. 168

42.632

87.156

0.372

Multiple sequence alignment