Detailed information NTG0216226

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: BZG42_RS06490
• Genome accession: NZ_CP019557
• Coordinates: 1374215..1376449 (-)
• Length: 744 a.a.
• NCBI ID: WP_155995986.1
• Uniprot ID: -
• Organism: Streptococcus sp. DAT741
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1369215..1381449

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BZG42_RS06460	-	1369921..1370085 (-)	165	WP_006627244.1	transposon-encoded TnpW family protein	-
BZG42_RS06465 (BZG42_06540)	-	1370212..1370835 (-)	624	WP_155995982.1	helix-turn-helix transcriptional regulator	-
BZG42_RS10255 (BZG42_06545)	-	1371081..1371277 (-)	197	Protein_1234	recombinase	-
BZG42_RS06475 (BZG42_06550)	sodA	1371463..1372074 (-)	612	WP_024532641.1	superoxide dismutase SodA	-
BZG42_RS06480 (BZG42_06555)	holA	1372171..1373202 (-)	1032	WP_120172488.1	DNA polymerase III subunit delta	-
BZG42_RS06485 (BZG42_06560)	-	1373458..1374069 (-)	612	WP_155995984.1	hypothetical protein	-
BZG42_RS06490 (BZG42_06565)	comEC/celB	1374215..1376449 (-)	2235	WP_155995986.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
BZG42_RS06495 (BZG42_06570)	comEA	1376433..1377089 (-)	657	WP_024532637.1	helix-hairpin-helix domain-containing protein	Machinery gene
BZG42_RS06500 (BZG42_06575)	-	1377174..1377917 (-)	744	WP_024532636.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
BZG42_RS06505 (BZG42_06580)	-	1378107..1379552 (+)	1446	WP_155995988.1	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	-
BZG42_RS06510 (BZG42_06585)	-	1379911..1380699 (+)	789	WP_155995990.1	ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 744 a.a.
• Molecular weight: 84934.80 Da
• Isoelectric Point: 9.7221

>NTDB_id=216226 BZG42_RS06490 WP_155995986.1 1374215..1376449(-) (comEC/celB) [Streptococcus sp. DAT741]
MLRLDKLPCQPIHLAILAVVTYFTVHRFSMLTMSLLILLLVIYWRRQGKLTFFKMLPLLVLCGLFFGCQKLKWKQEEQAV
SKQVTAVEIVPDTININGDQLSFRARTDGQIYQGFYKLTSQKEQEYFQKLTALVQVEVKAETSLPSGQRNFNGFDYQAYL
KTQGIYRILTITTINKIVPIHSWNPMDWLSIWRRKALVFIKSNFPSPMSHYMTGLLFGELDSDFDQMSALYSSLGIIHLF
ALSGMQVGFFIDKFRWILLRLGLTKETVDQLQVPFSLVYAGLTGFSVSVVRSLIQKILSNLGLRKLDNFAATLFICFLVQ
PRFLLTVGGVLTFTYAFLLTVFDFEDLKQIKKVVVESLSISLGILPILMTYFFAFQPLSILLTFFFSFVFDVLLLPSLSV
IFILSPLVKITWVNSFFVLMEKMIIWVSDLGFRPLILGKPSDFILLVLLLGFFMLYDFHRQKKWLLGLSLLLTLLFFITK
HPLENEVTVVDIGQGDSIFLRDMQGRTVLIDVGGRVDFTVKEGWKARSRQANAERTLIPYLHSRGVDKIDSLVLTHTDTD
HVGDVLEVAKNFKIGKIYVSSGSLTVPSFVTTLKKINVPVHVVQVGDRLPIVDSYLEVLYPSRSGDGSNNDSIVLYGRLL
GINFLFTGDLEEGELELIKTYPKLSVDVLKAGHHGSKGSSYPEFLDHIGAKIALISAGEKNRYKHPHQETLERFEQKNMQ
IYRTDRQGAIRFRGWRSWSIETVR

Nucleotide

• Length: 2235 bp

>NTDB_id=216226 BZG42_RS06490 WP_155995986.1 1374215..1376449(-) (comEC/celB) [Streptococcus sp. DAT741]
ATGTTACGGTTGGATAAGCTCCCCTGTCAGCCTATACATCTAGCCATTTTGGCGGTCGTGACCTACTTTACGGTTCACCG
TTTTTCGATGTTGACAATGAGCCTTCTGATATTATTATTGGTAATCTATTGGCGGCGTCAGGGGAAACTTACTTTTTTTA
AAATGCTGCCGCTTCTAGTCTTATGCGGTCTATTCTTCGGCTGCCAAAAGCTCAAATGGAAACAGGAAGAGCAGGCTGTT
TCAAAGCAAGTGACTGCTGTAGAGATTGTGCCGGATACTATAAATATCAATGGCGATCAGTTATCTTTCCGTGCTAGGAC
TGATGGTCAGATTTATCAAGGTTTCTATAAGCTAACTAGTCAGAAAGAACAGGAGTATTTCCAAAAGCTAACAGCTCTTG
TTCAGGTGGAGGTGAAGGCAGAGACGAGTCTCCCATCAGGTCAGCGGAATTTCAATGGTTTTGATTATCAAGCCTATTTA
AAAACACAGGGAATCTATCGAATCCTCACCATAACGACTATCAATAAGATTGTACCTATTCACTCTTGGAACCCTATGGA
TTGGTTGTCAATTTGGCGGAGAAAAGCCTTGGTTTTCATCAAATCTAATTTTCCTTCCCCCATGAGCCATTACATGACAG
GGTTGCTTTTTGGAGAGTTGGACAGTGACTTTGATCAGATGAGCGCCCTTTACTCCAGTCTGGGGATTATCCATCTCTTT
GCTCTATCAGGAATGCAGGTAGGTTTTTTCATTGATAAGTTTCGCTGGATTTTACTGCGTTTAGGCTTGACAAAGGAGAC
AGTTGATCAATTACAAGTCCCCTTTTCTTTGGTCTATGCTGGTTTGACAGGCTTTTCTGTATCAGTCGTCCGGTCTTTGA
TTCAGAAAATTTTGAGCAACCTGGGGCTTCGGAAGCTGGATAATTTTGCTGCAACACTCTTTATTTGTTTCTTGGTGCAG
CCTCGTTTTCTCCTGACAGTTGGAGGTGTCTTGACATTTACCTATGCTTTTTTGTTGACAGTCTTTGATTTTGAGGATTT
GAAGCAAATCAAAAAGGTTGTAGTGGAAAGTCTGAGTATTTCTCTGGGGATTCTGCCAATTCTGATGACCTATTTTTTCG
CTTTTCAGCCTCTATCTATTCTACTAACCTTCTTCTTTTCCTTTGTTTTTGATGTATTGCTTTTACCGAGTCTATCTGTA
ATTTTTATTTTATCTCCTTTGGTCAAGATTACTTGGGTCAATTCTTTCTTTGTTTTGATGGAGAAAATGATTATTTGGGT
ATCGGATTTGGGTTTTCGACCTTTGATACTAGGGAAACCGTCTGACTTCATCTTGTTAGTCTTGTTACTGGGATTTTTCA
TGCTTTACGATTTTCATAGACAGAAAAAATGGCTGTTAGGACTGAGTTTGCTCCTTACTCTGCTATTTTTCATTACAAAA
CATCCATTAGAAAATGAAGTAACTGTGGTAGATATCGGACAGGGAGATAGTATCTTTTTGCGAGATATGCAGGGGCGTAC
GGTTCTAATTGACGTTGGTGGACGGGTGGATTTTACGGTTAAGGAAGGCTGGAAGGCGCGATCCCGTCAGGCTAATGCAG
AGAGGACCTTGATTCCTTATCTACATAGTCGAGGTGTGGACAAGATTGACAGTCTGGTGTTGACGCACACCGATACTGAC
CATGTGGGCGATGTTCTGGAAGTAGCTAAGAATTTTAAGATCGGAAAAATCTATGTGTCTTCAGGTAGTTTGACAGTCCC
TAGCTTTGTAACCACCTTGAAAAAAATCAATGTACCTGTTCATGTGGTGCAGGTGGGTGATCGCCTACCGATCGTTGATT
CCTATTTGGAAGTGCTCTATCCGAGCCGATCGGGTGATGGTAGCAACAATGATTCTATTGTCCTCTATGGACGGCTCCTT
GGAATCAATTTTCTGTTTACGGGTGATCTGGAGGAGGGGGAATTAGAGCTGATAAAAACCTATCCCAAATTGTCAGTTGA
TGTTCTAAAAGCCGGACACCATGGTTCAAAAGGTTCTTCTTATCCTGAATTTTTAGACCATATTGGAGCTAAGATTGCCT
TAATCTCGGCTGGCGAGAAAAATCGCTACAAGCATCCCCATCAAGAAACCTTGGAGCGTTTTGAACAGAAGAATATGCAA
ATCTATCGGACAGACCGGCAAGGAGCTATTCGCTTTAGAGGTTGGCGAAGTTGGTCAATTGAAACGGTGAGATGA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (31-175)

• Metallo-beta-lactamase superfamily (Lactamase_B) (493-697)

• Competence protein (Competence) (215-459)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	53.414	100	0.536
comEC/celB	Streptococcus mitis NCTC 12261	52.83	99.731	0.527
comEC/celB	Streptococcus pneumoniae TIGR4	51.682	99.866	0.516
comEC/celB	Streptococcus pneumoniae Rx1	51.144	99.866	0.511
comEC/celB	Streptococcus pneumoniae D39	51.144	99.866	0.511
comEC/celB	Streptococcus pneumoniae R6	51.144	99.866	0.511
comEC	Lactococcus lactis subsp. cremoris KW2	47.233	99.597	0.47