Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   CBU_1998 Genome accession   NC_002971
Coordinates   1904218..1905144 (+) Length   308 a.a.
NCBI ID   NP_820973.1    Uniprot ID   Q83AA7
Organism   Coxiella burnetii RSA 493     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1899218..1910144
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CBU_1987c - 1899811..1900083 (-) 273 YP_002333047.1 hypothetical protein -
  CBU_1991 relB 1900273..1900527 (+) 255 NP_820966.1 toxin-antitoxin system antitoxin RelB -
  CBU_1992 relE 1900527..1900802 (+) 276 NP_820967.1 toxin-antitoxin system antitoxin RelE -
  CBU_1993 folA 1900775..1901260 (-) 486 NP_820968.1 dihydrofolate reductase -
  CBU_1994 - 1901257..1902060 (-) 804 NP_820969.2 hypothetical protein -
  CBU_1995 - 1902256..1902543 (+) 288 NP_820970.2 acylphosphatase -
  CBU_1996 - 1902519..1903073 (-) 555 NP_820971.1 phosphatase family protein -
  CBU_1997 fmt 1903086..1904030 (-) 945 NP_820972.1 methionyl-tRNA formyltransferase -
  CBU_1998 dprA 1904218..1905144 (+) 927 NP_820973.1 DNA processing protein Machinery gene
  CBU_1999 smg 1905141..1905620 (+) 480 NP_820974.2 Smg protein -
  CBU_2000 topA 1905623..1907920 (+) 2298 NP_820975.1 DNA topoisomerase I -
  CBU_2001 - 1907927..1908097 (-) 171 NP_820976.1 hypothetical protein -
  CBU_2002 purE 1908128..1908628 (+) 501 NP_820977.1 phosphoribosylaminoimidazole carboxylase carboxyltransferase subunit -
  CBU_2003 - 1908631..1909191 (+) 561 NP_820978.1 sua5/YciO/YrdC/YwlC family protein -
  CBU_2003a - 1909634..1909774 (+) 141 YP_002333048.1 hypothetical protein -

Sequence

Protein


Download         Length: 308 a.a.        Molecular weight: 33018.28 Da        Isoelectric Point: 7.5121

>NTDB_id=21357 CBU_1998 NP_820973.1 1904218..1905144(+) (dprA) [Coxiella burnetii RSA 493]
MQPPFNALLFFAMPNSQLDPEWTTAPNHHILTLDHPSYPTLLKEIPDPPKKLYIMGDPLILNQPQFAIVGSRNPTVTGCE
IAQEMAEKLVQAGFHITSGLALGIDAASHRGALKAGGQTIAVLGSGLTNIYPPRHHRLAEQISQKGALVSEFPLTMPPLP
TNFPRRNRIIIGLSLGTLVVEATLGSGSLITAKLAAEQNREVFAIPGSIRNPLSQGCHALIKEGAKLVDSIGDIIAELSY
EATGASAPIQALDKNEHKLLECIGFEVTSIDQLIARSGFSASIVASLLLRIELQGYIKSRPGGVIRVK

Nucleotide


Download         Length: 927 bp        

>NTDB_id=21357 CBU_1998 NP_820973.1 1904218..1905144(+) (dprA) [Coxiella burnetii RSA 493]
TTGCAACCTCCCTTCAATGCACTATTATTTTTCGCCATGCCAAATTCTCAATTAGACCCAGAATGGACGACAGCGCCGAA
CCACCATATTTTGACGCTCGATCATCCCTCCTACCCTACTTTATTGAAGGAAATCCCCGATCCGCCCAAAAAGCTCTACA
TCATGGGTGACCCTTTGATATTAAATCAGCCGCAATTTGCCATCGTCGGCAGCCGTAATCCAACCGTCACCGGCTGCGAA
ATCGCACAAGAAATGGCAGAGAAACTCGTTCAAGCTGGTTTTCACATCACCAGCGGCCTTGCACTTGGCATCGATGCCGC
AAGTCACCGCGGGGCTTTAAAAGCAGGAGGCCAAACCATAGCCGTACTCGGCAGCGGCTTAACTAACATATATCCTCCAC
GCCACCACCGTCTGGCGGAACAAATTTCCCAAAAAGGCGCCCTCGTCTCAGAATTCCCGCTAACCATGCCGCCACTCCCC
ACCAACTTCCCTCGCCGCAACCGCATCATCATCGGATTAAGCCTCGGTACGCTCGTGGTGGAAGCTACCCTTGGCTCAGG
CTCTCTGATCACCGCGAAATTAGCCGCCGAACAAAACCGGGAAGTTTTCGCCATCCCGGGTTCAATCCGAAACCCTCTTT
CTCAGGGATGCCATGCTCTCATCAAAGAGGGCGCTAAACTGGTTGATTCTATAGGGGATATTATTGCAGAATTGAGTTAT
GAGGCTACGGGCGCTAGCGCCCCGATTCAAGCACTTGATAAGAATGAACACAAACTGTTAGAGTGCATCGGATTTGAGGT
CACTTCCATTGATCAACTGATCGCTCGAAGTGGCTTTTCGGCTTCCATCGTAGCTTCGTTATTGTTAAGGATAGAATTGC
AAGGCTACATTAAATCAAGACCTGGCGGTGTTATACGAGTGAAGTGA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(25-229)

DprA winged helix domain (DprA_WH)

(245-303)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q83AA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Legionella pneumophila strain ERS1305867

53.925

95.13

0.513
  dprA Vibrio cholerae strain A1552

48.829

97.078

0.474
  dprA Vibrio campbellii strain DS40M4

47.386

99.351

0.471
  dprA Glaesserella parasuis strain SC1401

44.951

99.675

0.448
  dprA Acinetobacter baumannii D1279779

44.369

95.13

0.422
  dprA Acinetobacter baumannii strain A118

43.878

95.455

0.419
  dprA Acinetobacter baylyi ADP1

42.712

95.779

0.409
  dprA Haemophilus influenzae Rd KW20

55.046

70.779

0.39
  dprA Neisseria meningitidis strain C311

48.684

74.026

0.36
  dprA Neisseria meningitidis MC58

48.684

74.026

0.36

Multiple sequence alignment