Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   BSR19_RS00370 Genome accession   NZ_CP018187
Coordinates   63225..64490 (+) Length   421 a.a.
NCBI ID   WP_060972896.1    Uniprot ID   -
Organism   Streptococcus salivarius strain ICDC2     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 58225..69490
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BSR19_RS00340 (BSR19_00340) - 58556..58993 (-) 438 WP_013989911.1 LytTR family DNA-binding domain-containing protein -
  BSR19_RS00345 (BSR19_00345) - 59172..59477 (+) 306 WP_037603797.1 hypothetical protein -
  BSR19_RS00350 (BSR19_00350) mutL 59529..61466 (+) 1938 WP_060972893.1 DNA mismatch repair endonuclease MutL -
  BSR19_RS00355 (BSR19_00355) - 61597..61818 (+) 222 WP_037597288.1 hypothetical protein -
  BSR19_RS00360 (BSR19_00360) ruvA 61975..62565 (+) 591 WP_060972894.1 Holliday junction branch migration protein RuvA -
  BSR19_RS00365 (BSR19_00365) - 62574..63128 (+) 555 WP_060972895.1 DNA-3-methyladenine glycosylase I -
  BSR19_RS00370 (BSR19_00370) cinA 63225..64490 (+) 1266 WP_060972896.1 competence/damage-inducible protein A Machinery gene
  BSR19_RS00375 (BSR19_00375) recA 64531..65670 (+) 1140 WP_060972897.1 recombinase RecA Machinery gene
  BSR19_RS00380 (BSR19_00380) spx 65840..66238 (+) 399 WP_002886328.1 transcriptional regulator Spx -

Sequence

Protein


Download         Length: 421 a.a.        Molecular weight: 45571.80 Da        Isoelectric Point: 5.9555

>NTDB_id=206821 BSR19_RS00370 WP_060972896.1 63225..64490(+) (cinA) [Streptococcus salivarius strain ICDC2]
MKAELIAVGTEILTGQITNTNAQFLSEKLAELGIDVYFHTAVGDNENRLLSVLDQASKRSDLVILCGGLGPTEDDLTKQT
LAKFLGKELIFDEEASKKLDSFFATRPKHTRTPNNERQAQIVEGAIPLQNPTGLAVGGVITAQGVTYVVLPGPPSELKPM
VNQELVPALTENHASLYSRVLRFFGVGESQLVTILKDFIVNQTDPTIAPYAKVGEVTLRLSTKASSREEADQKLDVLEKQ
IRSTKTLDGKSLSDFIYGYGESNSLAFEAFRLLKNHGKTITAAESLTAGLFQASIADFSGASQVFKGGFVTYSIEEKSKM
LDIPLSQLEKHGVVSHFTAEKMAEGARAKTDSDYGIALTGVAGPDSLEGHPAGTVFIGIADRNQVRSIKVVIGGRSRSDV
RYISTLYAFNLVRQALLQETT

Nucleotide


Download         Length: 1266 bp        

>NTDB_id=206821 BSR19_RS00370 WP_060972896.1 63225..64490(+) (cinA) [Streptococcus salivarius strain ICDC2]
ATGAAAGCTGAATTGATTGCAGTAGGAACCGAAATCCTAACCGGGCAAATCACCAATACCAATGCCCAATTTTTATCTGA
GAAACTAGCTGAACTAGGAATTGACGTGTATTTTCACACAGCAGTAGGAGACAATGAAAACCGCCTACTCTCAGTTCTAG
ACCAAGCTAGTAAACGTAGTGACTTAGTCATACTTTGTGGAGGACTTGGTCCTACTGAGGATGACTTAACCAAGCAAACA
CTGGCTAAGTTTTTAGGCAAAGAACTCATTTTTGATGAGGAGGCAAGTAAAAAATTGGACAGTTTCTTTGCTACTCGTCC
TAAACACACACGAACGCCTAATAATGAACGTCAAGCGCAAATTGTTGAGGGGGCTATCCCTTTGCAAAATCCTACAGGTC
TTGCAGTTGGAGGCGTCATTACTGCTCAAGGGGTGACCTATGTAGTCTTACCTGGTCCACCAAGTGAACTCAAACCTATG
GTGAATCAGGAACTTGTTCCAGCACTTACTGAGAATCACGCAAGTCTTTATTCGAGAGTCCTAAGATTCTTTGGCGTTGG
AGAAAGTCAATTGGTGACTATTCTGAAGGATTTTATTGTTAACCAAACAGATCCAACCATAGCTCCATACGCTAAAGTGG
GGGAAGTAACACTTCGCTTGTCTACAAAGGCTTCTTCACGAGAAGAAGCAGATCAAAAACTAGATGTTTTAGAAAAACAA
ATTCGTTCTACTAAAACTCTAGATGGCAAATCCTTATCTGATTTTATTTATGGGTATGGAGAGTCTAATAGTTTAGCCTT
TGAAGCTTTTCGTTTGCTTAAGAACCATGGCAAGACTATCACTGCAGCTGAAAGCCTAACAGCAGGTTTATTTCAGGCTA
GTATTGCTGATTTTTCAGGAGCCTCACAAGTATTTAAAGGCGGCTTTGTTACTTACAGCATTGAAGAAAAATCTAAAATG
TTGGATATTCCCTTGTCGCAACTAGAAAAACATGGTGTTGTCAGTCATTTTACTGCAGAAAAAATGGCTGAAGGTGCCCG
AGCTAAAACAGATAGCGATTACGGAATTGCACTTACCGGTGTAGCTGGACCAGATTCATTAGAAGGACACCCAGCAGGTA
CAGTATTTATTGGTATTGCTGATAGGAATCAAGTAAGGTCAATCAAGGTTGTTATAGGTGGAAGAAGTCGTTCTGACGTT
AGATATATTAGTACCCTCTATGCCTTTAACCTAGTTCGCCAAGCTTTATTACAAGAGACAACTTGA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-243)

Competence-damaged protein (CinA)

(264-415)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

74.463

99.525

0.741
  cinA Streptococcus mitis NCTC 12261

73.747

99.525

0.734
  cinA Streptococcus pneumoniae TIGR4

73.27

99.525

0.729
  cinA Streptococcus pneumoniae Rx1

73.031

99.525

0.727
  cinA Streptococcus pneumoniae R6

73.031

99.525

0.727
  cinA Streptococcus pneumoniae D39

72.792

99.525

0.724
  cinA Streptococcus mutans UA159

71.223

99.05

0.705
  cinA Streptococcus suis isolate S10

55.048

98.812

0.544
  cinA Bacillus subtilis subsp. subtilis str. 168

44.893

100

0.449

Multiple sequence alignment