Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   SMA_2113 Genome accession   HE613569
Coordinates   2054650..2055909 (-) Length   419 a.a.
NCBI ID   CCF03404.1    Uniprot ID   -
Organism   Streptococcus macedonicus ACA-DC 198     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2049650..2060909
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMA_2107 - 2051275..2051409 (-) 135 CCF03398.1 Hypothetical protein -
  SMA_2108 - 2051422..2051739 (-) 318 CCF03399.1 Hypothetical protein -
  SMA_2109 yggF 2051772..2052191 (-) 420 CCF03400.1 putative Holliday junction resolvase -
  SMA_2110 - 2052188..2052457 (-) 270 CCF03401.1 Hypothetical protein possible functionally linked with Alanyl-tRNA synthetase -
  SMA_2111 spxA2 2052779..2053177 (-) 399 CCF03402.1 Transcriptional regulator SpxA2 -
  SMA_2112 recA 2053446..2054600 (-) 1155 CCF03403.1 RecA protein Machinery gene
  SMA_2113 cinA 2054650..2055909 (-) 1260 CCF03404.1 Competence/damage-inducible protein CinA Machinery gene
  SMA_2114 - 2056067..2056504 (-) 438 CCF03405.1 Facilitator superfamily protein -
  SMA_2115 - 2056443..2056673 (-) 231 CCF03406.1 Facilitator superfamily protein -
  SMA_2116 - 2056631..2057005 (-) 375 CCF03407.1 Facilitator superfamily protein -
  SMA_2117 - 2057387..2057689 (-) 303 CCF03408.1 Hypothetical protein -
  SMA_2118 - 2057708..2057851 (-) 144 CCF03409.1 Hypothetical protein -
  SMA_2119 - 2058112..2058768 (+) 657 CCF03410.1 Hypothetical protein -
  SMA_2120 ruvA 2058873..2059466 (-) 594 CCF03411.1 Holliday junction DNA helicase RuvA -

Sequence

Protein


Download         Length: 419 a.a.        Molecular weight: 45466.90 Da        Isoelectric Point: 5.3127

>NTDB_id=20374 SMA_2113 CCF03404.1 2054650..2055909(-) (cinA) [Streptococcus macedonicus ACA-DC 198]
MKAEIIAVGTEILTGQITNTNAQFLSEEFAKLGIDVFFQTAVGDNEERLLSVINLASKRSELVVLCGGLGPTEDDLTKQT
LAKYLGRDLVFDEQANKRLDEFFATRPQFARTANNERQAQLIEGSIPLQNSTGLAVGGVLEVNGVTYVVLPGPPSELKPM
VLDSLVPLLSEGHRQLYSRVLRFFGIGESQLVTVLTDLIDNQTDPTIAPYAKTGEVTLRLSTKANDVTSAKAKLDALEHK
ILAKKTLNGILLEQLLYGYGDDNSMARVVFELLKEKHKTITAAESLTAGLFQSSIADFSGSSAVFNGGFVTYSIEEKSKM
LHIPLEDLQEHGVVSHFTAEKMAEQSRLLTDADFGIGLTGVAGPNSLEGHPAGTVFIGIATREKVHSIRVVLGGRSRSDV
RYIATLYAFNLVRQALLQG

Nucleotide


Download         Length: 1260 bp        

>NTDB_id=20374 SMA_2113 CCF03404.1 2054650..2055909(-) (cinA) [Streptococcus macedonicus ACA-DC 198]
ATGAAAGCTGAAATCATTGCTGTGGGAACAGAAATTCTAACAGGACAAATCACAAATACAAATGCTCAATTTTTATCGGA
AGAATTTGCCAAGTTAGGAATTGATGTGTTCTTTCAAACAGCTGTTGGTGATAATGAAGAACGTCTTTTATCAGTTATTA
ATTTAGCAAGCAAGCGAAGTGAATTAGTTGTCTTATGTGGAGGGCTTGGTCCGACAGAAGACGATTTAACAAAACAAACG
TTAGCAAAATATTTGGGACGCGATTTAGTCTTTGATGAACAAGCTAACAAGCGTTTGGACGAATTTTTTGCGACACGTCC
GCAGTTTGCTAGAACGGCTAATAACGAACGTCAAGCACAGCTGATTGAAGGGTCAATACCGTTGCAAAATAGCACTGGTT
TGGCTGTTGGTGGCGTGCTAGAAGTAAATGGCGTGACCTATGTTGTTCTCCCTGGACCGCCGAGTGAATTAAAACCAATG
GTATTGGATTCTCTAGTACCTTTATTGTCTGAAGGCCATAGGCAGCTTTATTCACGTGTGTTGCGTTTCTTTGGTATTGG
TGAAAGCCAGTTAGTGACCGTTTTGACAGATTTGATTGATAATCAAACAGACCCAACGATTGCTCCGTATGCGAAAACAG
GTGAGGTGACCCTTCGTTTATCAACCAAGGCAAATGATGTGACGTCAGCAAAAGCGAAATTGGATGCTCTAGAGCATAAA
ATTCTAGCTAAAAAAACATTAAATGGTATTCTTCTTGAACAGTTACTTTATGGCTATGGTGATGATAACAGTATGGCGCG
TGTTGTTTTTGAGTTGTTGAAAGAAAAGCACAAAACCATTACAGCGGCAGAAAGTTTGACTGCAGGGCTATTCCAATCTA
GTATCGCTGATTTTTCAGGGTCATCTGCAGTATTTAATGGCGGATTTGTGACGTATAGTATAGAAGAAAAATCAAAAATG
CTTCACATTCCTCTTGAAGATTTGCAAGAACATGGTGTAGTAAGTCACTTTACAGCTGAAAAAATGGCAGAGCAATCACG
TTTATTGACAGATGCTGATTTTGGTATCGGTTTGACAGGTGTTGCAGGACCAAATAGCTTAGAAGGACATCCAGCAGGAA
CAGTTTTTATTGGTATTGCTACTAGAGAAAAAGTTCATTCTATTCGTGTTGTTCTAGGTGGACGAAGCCGTTCAGACGTC
CGTTATATTGCTACTTTATATGCTTTCAACTTAGTACGTCAAGCTTTATTACAAGGCTAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-241)

Competence-damaged protein (CinA)

(263-415)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

71.942

99.523

0.716
  cinA Streptococcus mitis SK321

71.463

99.523

0.711
  cinA Streptococcus mitis NCTC 12261

71.223

99.523

0.709
  cinA Streptococcus pneumoniae Rx1

70.264

99.523

0.699
  cinA Streptococcus pneumoniae TIGR4

70.264

99.523

0.699
  cinA Streptococcus pneumoniae R6

70.264

99.523

0.699
  cinA Streptococcus pneumoniae D39

70.024

99.523

0.697
  cinA Streptococcus suis isolate S10

54.087

99.284

0.537
  cinA Bacillus subtilis subsp. subtilis str. 168

45.498

100

0.458

Multiple sequence alignment