Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   BK055_RS09380 Genome accession   NZ_CP017775
Coordinates   1855380..1856630 (+) Length   416 a.a.
NCBI ID   WP_071181768.1    Uniprot ID   -
Organism   Bacillus velezensis strain 9912D     
Function   unknown (predicted from homology)   
Unclear

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 1836656..1917040 1855380..1856630 within 0


Gene organization within MGE regions


Location: 1836656..1917040
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BK055_RS09300 (BK055_09300) dapA 1836892..1837761 (+) 870 WP_025649452.1 4-hydroxy-tetrahydrodipicolinate synthase -
  BK055_RS09305 (BK055_09305) rnjB 1837940..1839607 (+) 1668 WP_021493672.1 ribonuclease J2 -
  BK055_RS09310 (BK055_09310) - 1839723..1840460 (+) 738 WP_003154162.1 ClpP family protease -
  BK055_RS09315 (BK055_09315) - 1840457..1840666 (+) 210 WP_003154161.1 YlzJ-like family protein -
  BK055_RS09320 (BK055_09320) - 1840801..1843164 (+) 2364 WP_063636644.1 FtsK/SpoIIIE family DNA translocase -
  BK055_RS09325 (BK055_09325) - 1843289..1844014 (+) 726 WP_007409813.1 GntR family transcriptional regulator -
  BK055_RS09330 (BK055_09330) - 1844186..1845355 (+) 1170 WP_087920797.1 MFS transporter -
  BK055_RS09335 (BK055_09335) - 1845460..1845915 (+) 456 WP_013352309.1 MarR family winged helix-turn-helix transcriptional regulator -
  BK055_RS09340 (BK055_09340) - 1845915..1849034 (+) 3120 WP_071181766.1 MMPL family transporter -
  BK055_RS09345 (BK055_09345) yfmF 1849187..1850467 (+) 1281 WP_013352311.1 EF-P 5-aminopentanol modification-associated protein YfmF -
  BK055_RS09350 (BK055_09350) yfmH 1850464..1851750 (+) 1287 WP_013352312.1 EF-P 5-aminopentanol modification-associated protein YfmH -
  BK055_RS09355 (BK055_09355) ymfI 1851809..1852537 (+) 729 WP_013352313.1 elongation factor P 5-aminopentanone reductase -
  BK055_RS09360 (BK055_09360) - 1852613..1852870 (+) 258 WP_003154150.1 DUF3243 domain-containing protein -
  BK055_RS09365 (BK055_09365) - 1852998..1853789 (+) 792 WP_013352314.1 DUF3388 domain-containing protein -
  BK055_RS09370 (BK055_09370) - 1853808..1854707 (+) 900 WP_071181767.1 helix-turn-helix domain-containing protein -
  BK055_RS09375 (BK055_09375) pgsA 1854781..1855362 (+) 582 WP_007409821.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  BK055_RS09380 (BK055_09380) cinA 1855380..1856630 (+) 1251 WP_071181768.1 competence/damage-inducible protein A Machinery gene
  BK055_RS09385 (BK055_09385) recA 1856801..1857844 (+) 1044 WP_003154145.1 recombinase RecA Machinery gene
  BK055_RS09390 (BK055_09390) - 1858011..1859192 (+) 1182 WP_071181769.1 serine hydrolase domain-containing protein -
  BK055_RS09395 (BK055_09395) rny 1859485..1861044 (+) 1560 WP_003154140.1 ribonuclease Y -
  BK055_RS09400 (BK055_09400) - 1861105..1861899 (+) 795 WP_071181770.1 TIGR00282 family metallophosphoesterase -
  BK055_RS09405 (BK055_09405) spoVS 1862099..1862359 (+) 261 WP_003154135.1 stage V sporulation protein SpoVS -
  BK055_RS09410 (BK055_09410) tdh 1862616..1863662 (+) 1047 WP_014417804.1 L-threonine 3-dehydrogenase -
  BK055_RS09415 (BK055_09415) - 1863675..1864853 (+) 1179 WP_029325912.1 glycine C-acetyltransferase -
  BK055_RS09420 (BK055_09420) miaB 1864997..1866526 (+) 1530 WP_025649446.1 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB -
  BK055_RS09425 (BK055_09425) - 1866529..1866960 (+) 432 WP_003154113.1 RicAFT regulatory complex protein RicA family protein -
  BK055_RS09430 (BK055_09430) cotE 1867213..1867758 (+) 546 WP_003154111.1 outer spore coat protein CotE -
  BK055_RS09435 (BK055_09435) mutS 1867877..1870462 (+) 2586 WP_025649445.1 DNA mismatch repair protein MutS -
  BK055_RS09440 (BK055_09440) mutL 1870478..1872355 (+) 1878 WP_017417802.1 DNA mismatch repair endonuclease MutL -
  BK055_RS09445 (BK055_09445) - 1872600..1873141 (+) 542 Protein_1841 tyrosine-type recombinase/integrase -
  BK055_RS09450 (BK055_09450) - 1873398..1874129 (+) 732 WP_025649444.1 hypothetical protein -
  BK055_RS09455 (BK055_09455) - 1874553..1874762 (-) 210 WP_021493661.1 hypothetical protein -
  BK055_RS21395 - 1875315..1875464 (+) 150 WP_223255065.1 hypothetical protein -
  BK055_RS09460 (BK055_09460) - 1875448..1876125 (+) 678 WP_003154103.1 MBL fold metallo-hydrolase -
  BK055_RS09465 (BK055_09465) fabD 1876440..1877308 (+) 869 Protein_1846 ACP S-malonyltransferase -
  BK055_RS09470 (BK055_09470) - 1877445..1878419 (+) 975 WP_017417808.1 acyltransferase domain-containing protein -
  BK055_RS09475 (BK055_09475) fabD 1878421..1880661 (+) 2241 WP_025649443.1 ACP S-malonyltransferase -
  BK055_RS09480 (BK055_09480) - 1880727..1880975 (+) 249 WP_014417817.1 acyl carrier protein -
  BK055_RS09485 (BK055_09485) - 1881027..1882289 (+) 1263 WP_017417811.1 hydroxymethylglutaryl-CoA synthase family protein -
  BK055_RS09490 (BK055_09490) - 1882286..1883059 (+) 774 WP_025649442.1 enoyl-CoA hydratase/isomerase -
  BK055_RS09495 (BK055_09495) - 1883069..1883431 (+) 363 Protein_1852 enoyl-CoA hydratase-related protein -
  BK055_RS22645 - 1883382..1883546 (+) 165 Protein_1853 beta-ketoacyl synthase N-terminal-like domain-containing protein -
  BK055_RS09500 (BK055_09500) - 1883506..1885716 (+) 2211 Protein_1854 beta-ketoacyl synthase N-terminal-like domain-containing protein -
  BK055_RS09510 (BK055_09510) - 1885813..1886963 (+) 1151 WP_087614160.1 IS3 family transposase -
  BK055_RS09515 (BK055_09515) - 1886999..1892794 (+) 5796 Protein_1856 beta-ketoacyl synthase N-terminal-like domain-containing protein -
  BK055_RS09520 (BK055_09520) - 1892812..1903346 (+) 10535 Protein_1857 SDR family NAD(P)-dependent oxidoreductase -

Sequence

Protein


Download         Length: 416 a.a.        Molecular weight: 45203.61 Da        Isoelectric Point: 5.5331

>NTDB_id=202808 BK055_RS09380 WP_071181768.1 1855380..1856630(+) (cinA) [Bacillus velezensis strain 9912D]
MEIAKKAEIIAVGSELLLGQIANTNAQFISKELAEIGVNVFYHTAVGDNPERLKHVIRIAEERSDLIIFSGGLGPTKDDL
TKETIANTLGRPLVLNDEAFRSIEEYFVKTKRTMSPNNRKQALVIEGSEVLANHFGMAPGMLAEHGSRLYMLLPGPPSEL
RPMFENEAKPLLLKKLGSNEKIVSTVLRFFGIGESQLEADLEDIIDAQTNPTIAPLAADGEVTLRLTAKHADEKETERLL
KETEAAILERVGEFFYGYDDTSLVKELSKACRQNKITISSAESFTGGLFSEWVTDLRGASQLFAGGVVCYSDSVKQHVLG
VKAETLAESGAVSKECAKELAAGVRKLTGSDIGISFTGVAGPDPQEGHAPGRVFIGISAEGKEEVHEFNFAGSRTGIRKR
AAKYGCHLILKMLDQK

Nucleotide


Download         Length: 1251 bp        

>NTDB_id=202808 BK055_RS09380 WP_071181768.1 1855380..1856630(+) (cinA) [Bacillus velezensis strain 9912D]
ATGGAAATAGCAAAAAAAGCAGAGATCATTGCAGTCGGCTCGGAGCTTCTGCTCGGCCAGATCGCCAATACGAACGCGCA
GTTTATCAGTAAAGAGCTGGCGGAAATCGGTGTAAACGTGTTTTATCATACCGCTGTCGGTGACAATCCGGAGCGGCTTA
AGCATGTCATCCGCATTGCCGAAGAGCGCTCAGACCTGATTATTTTTTCAGGCGGCCTCGGGCCGACCAAGGACGATTTA
ACGAAAGAAACCATTGCAAACACACTGGGGCGCCCGCTCGTTCTGAATGACGAAGCATTCCGGTCGATCGAAGAATATTT
CGTGAAAACAAAACGGACCATGTCGCCGAATAACCGCAAACAGGCGCTCGTCATTGAGGGCTCAGAAGTTTTGGCGAATC
ATTTCGGCATGGCGCCGGGAATGCTTGCAGAGCACGGCTCAAGGCTTTATATGCTGCTTCCCGGGCCGCCGAGCGAGCTG
CGTCCGATGTTTGAAAATGAAGCGAAGCCGCTGCTTCTTAAAAAGCTCGGTTCTAATGAGAAAATCGTTTCAACCGTGCT
GCGGTTTTTCGGAATCGGTGAATCCCAGCTTGAAGCTGATTTAGAAGATATCATTGACGCGCAGACGAACCCGACGATTG
CGCCGCTCGCTGCTGACGGTGAGGTCACGCTGCGTTTAACGGCGAAACATGCCGACGAAAAAGAAACAGAACGGCTTTTA
AAAGAAACGGAAGCCGCCATTTTAGAACGTGTCGGTGAATTTTTCTACGGATATGATGATACGTCTCTGGTGAAGGAGCT
TTCAAAAGCATGCAGACAAAACAAAATCACGATTTCTTCTGCCGAAAGCTTTACAGGCGGCCTGTTTTCAGAGTGGGTGA
CTGATTTAAGAGGTGCGTCTCAACTATTTGCAGGGGGCGTTGTCTGTTATTCCGACAGCGTGAAACAGCATGTGCTCGGC
GTGAAAGCTGAGACGCTCGCAGAAAGCGGAGCGGTCAGCAAAGAGTGTGCGAAAGAGCTTGCAGCCGGTGTGAGAAAGCT
GACCGGAAGCGATATCGGCATCAGCTTTACCGGGGTTGCGGGTCCCGACCCGCAGGAAGGGCATGCTCCGGGCCGCGTCT
TTATCGGCATTTCAGCGGAAGGAAAAGAAGAGGTGCACGAATTTAACTTTGCCGGCTCAAGAACCGGAATCAGAAAGCGC
GCCGCTAAATACGGCTGCCATCTCATTTTAAAAATGCTGGATCAAAAATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(9-172)

Damage-inducible protein CinA KH domain (CinA_KH)

(184-257)

Competence-damaged protein (CinA)

(261-413)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Bacillus subtilis subsp. subtilis str. 168

89.423

100

0.894
  cinA Streptococcus mitis NCTC 12261

47.129

100

0.474
  cinA Streptococcus mitis SK321

46.651

100

0.469
  cinA Streptococcus pneumoniae TIGR4

46.411

100

0.466
  cinA Streptococcus pneumoniae Rx1

46.172

100

0.464
  cinA Streptococcus pneumoniae R6

46.172

100

0.464
  cinA Streptococcus pneumoniae D39

45.933

100

0.462
  cinA Streptococcus mutans UA159

46.005

99.279

0.457
  cinA Streptococcus suis isolate S10

40.665

93.99

0.382

Multiple sequence alignment