Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   Spy49_1754c Genome accession   CP000829
Coordinates   1745629..1746900 (-) Length   423 a.a.
NCBI ID   ACI62004.1    Uniprot ID   -
Organism   Streptococcus pyogenes NZ131     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 1740629..1751900
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Spy49_1749c - 1742600..1742905 (-) 306 ACI61999.1 Conserved hypothetical protein -
  Spy49_1750c - 1742917..1743336 (-) 420 ACI62000.1 Putative Holliday junction resolvase -
  Spy49_1751c - 1743333..1743602 (-) 270 ACI62001.1 UPF0297 protein SPy2114 -
  Spy49_1752c - 1743716..1744114 (-) 399 ACI62002.1 Conserved hypothetical protein -
  Spy49_1753c recA 1744405..1745541 (-) 1137 ACI62003.1 RecA protein Machinery gene
  Spy49_1754c cinA 1745629..1746900 (-) 1272 ACI62004.1 CinA-like protein Machinery gene
  Spy49_1755c tag 1746969..1747529 (-) 561 ACI62005.1 DNA-3-methyladenine glycosylase -
  Spy49_1756c ruvA 1747539..1748135 (-) 597 ACI62006.1 Holliday junction DNA helicase ruvA -
  Spy49_1757c lmrP 1748137..1749357 (-) 1221 ACI62007.1 Putative integral membrane protein -
  Spy49_1758c mutL 1749368..1751350 (-) 1983 ACI62008.1 DNA mismatch repair protein MutL -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 45953.68 Da        Isoelectric Point: 4.7046

>NTDB_id=20167 Spy49_1754c ACI62004.1 1745629..1746900(-) (cinA) [Streptococcus pyogenes NZ131]
MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLLSVITTASQRSDLVILCGGLGPTKDDLTKQT
LAKYLRKDLVYDEQACQKLDDFFAKRKPSSRTPNNERQAQVIEGSISLPNKTGLAVGGFITVDGISYVVLPGPPSELKPM
VNEELVPLLSKQYSTLYSKVLRFFGIGESQLVTVLSDFIENQTDPTIAPYAKTGEVTLRLSTKTENQALADKKLGQLEAQ
LLSRKTLEGQPLADVFYGYGEDNSLARETFELLVKYDKTITAAESLTAGLFQSTLASFPGASQVFNGGFVTYSMEEKAKM
LGLPLEELKSYGVVSAYTAEGMAEQARLLTGADIGVSLTGVAGPDMLEEQPAGTVFIGLATQNKVESIKVLISGRSRLDV
CYIATLHAFNMVRKTLLKLENLL

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=20167 Spy49_1754c ACI62004.1 1745629..1746900(-) (cinA) [Streptococcus pyogenes NZ131]
ATGAAAGCTGAACTGATTGCAGTAGGTACCGAAATTTTGACTGGTCAAATTGTGAATACCAATGCTCAATTTCTGTCGGA
AAAAATGGCAGAGCTAGGTATTGATGTCTATTTTCAAACGGCTGTTGGGGACAACGAGGAGCGTTTACTTTCAGTGATTA
CAACTGCTAGTCAGCGTAGTGACTTGGTGATTTTATGTGGTGGCCTTGGTCCAACGAAAGATGATTTAACCAAACAAACT
TTAGCAAAGTACCTTAGGAAAGACTTGGTTTATGATGAGCAAGCTTGTCAGAAACTAGATGACTTTTTTGCTAAGCGCAA
GCCTTCATCACGGACACCAAATAATGAGCGACAGGCACAAGTGATTGAAGGGTCAATCTCTTTGCCAAATAAAACTGGTC
TTGCGGTTGGTGGGTTCATCACAGTCGATGGTATTAGTTATGTTGTCTTACCGGGTCCTCCAAGTGAATTGAAGCCGATG
GTAAATGAAGAATTGGTACCACTTCTGTCAAAACAATACAGTACATTGTATTCAAAGGTACTACGCTTTTTTGGTATTGG
GGAAAGTCAGTTGGTAACAGTCTTGTCAGATTTTATTGAGAATCAAACTGATCCAACCATTGCTCCGTATGCTAAGACTG
GCGAAGTGACTCTTCGCTTATCAACAAAAACTGAAAACCAAGCTCTGGCAGATAAAAAGTTAGGTCAGCTAGAAGCGCAG
CTACTATCCCGAAAAACTCTTGAAGGTCAACCCTTAGCTGATGTCTTTTATGGCTATGGGGAGGATAATTCCTTAGCGCG
TGAGACATTTGAGCTCTTAGTAAAATATGATAAGACAATTACAGCAGCAGAAAGTCTAACCGCGGGATTATTTCAGTCAA
CTTTGGCGAGTTTTCCAGGAGCTTCTCAAGTATTCAATGGAGGCTTTGTGACTTATAGCATGGAAGAAAAAGCGAAAATG
CTAGGCCTTCCTTTAGAGGAGTTGAAATCGTATGGCGTTGTTAGTGCTTATACGGCCGAGGGGATGGCGGAGCAAGCAAG
GTTATTGACTGGTGCTGATATTGGGGTAAGTTTAACAGGTGTTGCCGGACCAGATATGTTGGAGGAACAGCCTGCAGGTA
CAGTTTTCATTGGTCTTGCCACTCAAAATAAGGTAGAATCAATAAAGGTTTTGATTAGCGGGCGAAGTCGTTTGGATGTG
TGCTATATCGCTACTTTACATGCCTTTAATATGGTCCGTAAAACTTTATTAAAACTTGAGAATTTGCTATAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(263-416)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-243)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

69.031

100

0.69
  cinA Streptococcus mitis SK321

69.544

98.582

0.686
  cinA Streptococcus mitis NCTC 12261

69.065

98.582

0.681
  cinA Streptococcus pneumoniae TIGR4

67.866

98.582

0.669
  cinA Streptococcus pneumoniae Rx1

67.866

98.582

0.669
  cinA Streptococcus pneumoniae R6

67.866

98.582

0.669
  cinA Streptococcus pneumoniae D39

67.626

98.582

0.667
  cinA Streptococcus suis isolate S10

53.125

98.345

0.522
  cinA Bacillus subtilis subsp. subtilis str. 168

46.411

98.818

0.459

Multiple sequence alignment