Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   BKM66_RS00405 Genome accession   NZ_CP017666
Coordinates   69938..71119 (+) Length   393 a.a.
NCBI ID   WP_105184190.1    Uniprot ID   A0AAD0PAA2
Organism   Streptococcus suis strain 0061     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 64938..76119
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BKM66_RS00385 (BKM66_00380) mutL 66331..68268 (+) 1938 WP_014637283.1 DNA mismatch repair endonuclease MutL -
  BKM66_RS00390 (BKM66_00385) ruvA 68307..68897 (+) 591 WP_024403269.1 Holliday junction branch migration protein RuvA -
  BKM66_RS00400 (BKM66_00395) - 69332..69901 (+) 570 WP_105184191.1 DNA-3-methyladenine glycosylase I -
  BKM66_RS00405 (BKM66_00400) cinA 69938..71119 (+) 1182 WP_105184190.1 competence/damage-inducible protein A Machinery gene
  BKM66_RS00410 (BKM66_00405) recA 71171..72322 (+) 1152 WP_105184189.1 recombinase RecA Machinery gene
  BKM66_RS00415 (BKM66_00410) spx 72558..72956 (+) 399 WP_105184188.1 transcriptional regulator Spx -
  BKM66_RS00420 (BKM66_00415) - 73056..73322 (+) 267 WP_002939360.1 IreB family regulatory phosphoprotein -
  BKM66_RS00425 (BKM66_00420) ruvX 73322..73741 (+) 420 WP_002939356.1 Holliday junction resolvase RuvX -
  BKM66_RS00430 (BKM66_00425) - 73753..74073 (+) 321 WP_002939343.1 DUF1292 domain-containing protein -
  BKM66_RS10485 - 74332..74454 (+) 123 WP_257571720.1 hypothetical protein -
  BKM66_RS00435 (BKM66_00430) rpsJ 74663..74971 (+) 309 WP_014735259.1 30S ribosomal protein S10 -
  BKM66_RS00440 (BKM66_00435) rplC 75108..75734 (+) 627 WP_011921686.1 50S ribosomal protein L3 -

Sequence

Protein


Download         Length: 393 a.a.        Molecular weight: 42958.78 Da        Isoelectric Point: 4.3708

>NTDB_id=201279 BKM66_RS00405 WP_105184190.1 69938..71119(+) (cinA) [Streptococcus suis strain 0061]
MKAELIAVGTEILTGQIVNTNAQFLSEKCAELGIDVYFHTAVGDNENRLLSVLEVASQRSELVILCGGLGPTEDDLTKQT
LATFLGRNLVFDELAMAKLDRFFASRPGRVRTPNNERQAQIVEGSQALQNPAGLAVGGMIEQDGVTYIVLPGPPSELKAM
FSESLLPLLSQSQQQLYSRVLRFFGIGESQLVTVLADLIDKQTDPTLAPYAKVGEVTLRLSTKATSQEEANLRLNQLEED
ILQHDKLADYFYAYGEDNSLVKTVATRLAEKRQTIAIVEQGTGGLLQAELSLTLADQPYFSGGRVIGQLGTESGRLSEEA
DCIRQELQADLGLAVSVLIKPESTEDNVLAKVYLTLATPSGISQKEIDLGGYSWQYLRQLACLQAWDFVRNTL

Nucleotide


Download         Length: 1182 bp        

>NTDB_id=201279 BKM66_RS00405 WP_105184190.1 69938..71119(+) (cinA) [Streptococcus suis strain 0061]
ATGAAAGCAGAACTAATCGCCGTTGGGACGGAGATTTTGACAGGTCAAATCGTTAATACCAATGCTCAGTTCCTTTCGGA
GAAATGTGCAGAGCTGGGAATTGATGTTTATTTCCACACAGCTGTTGGAGATAATGAAAACAGGCTTCTGTCTGTACTGG
AAGTAGCCAGTCAGCGTAGTGAGCTAGTCATTCTCTGTGGAGGATTGGGTCCAACAGAAGATGACTTGACCAAGCAGACC
TTGGCGACCTTCTTAGGTAGAAATCTTGTGTTTGATGAGTTGGCTATGGCAAAATTAGACCGTTTCTTTGCCAGTCGCCC
AGGTCGTGTCCGTACACCAAATAATGAACGTCAGGCACAGATTGTGGAAGGAAGTCAGGCGCTACAGAATCCAGCTGGTT
TAGCTGTTGGTGGTATGATTGAGCAAGATGGTGTAACCTATATTGTTTTGCCTGGCCCACCAAGTGAGCTCAAGGCCATG
TTTTCTGAGAGTCTCTTACCTTTACTGTCCCAATCTCAGCAGCAACTTTATTCGCGTGTCCTACGCTTTTTTGGAATTGG
CGAAAGCCAGTTAGTGACTGTTTTGGCGGACTTGATTGACAAGCAGACAGACCCAACTCTTGCTCCTTATGCAAAAGTTG
GAGAGGTGACTTTACGCTTGTCCACCAAAGCGACCAGCCAAGAAGAAGCAAATCTACGTTTAAATCAGTTGGAAGAAGAC
ATCTTACAACATGACAAACTGGCAGACTATTTCTATGCCTACGGAGAGGACAATAGTTTGGTCAAAACGGTAGCGACTCG
TTTGGCGGAGAAAAGACAAACCATCGCTATCGTCGAACAGGGGACAGGTGGTCTCTTGCAAGCTGAATTGAGCCTGACTT
TGGCTGATCAGCCGTATTTTAGCGGAGGAAGAGTTATCGGTCAGCTAGGGACAGAATCGGGCAGGCTATCAGAGGAAGCT
GACTGCATTCGGCAGGAGCTGCAAGCTGATTTAGGTTTGGCTGTGTCTGTGCTTATCAAACCGGAATCAACAGAGGACAA
CGTACTTGCAAAAGTATATCTCACTTTGGCTACGCCCTCGGGTATTTCCCAAAAAGAGATAGATTTAGGTGGTTATTCGT
GGCAATACCTTCGCCAGCTTGCTTGTCTGCAGGCCTGGGATTTTGTACGAAACACTTTGTGA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus suis isolate S10

96.692

100

0.967
  cinA Streptococcus mutans UA159

57.178

100

0.598
  cinA Streptococcus pneumoniae R6

56.49

100

0.598
  cinA Streptococcus mitis SK321

56.49

100

0.598
  cinA Streptococcus pneumoniae TIGR4

56.49

100

0.598
  cinA Streptococcus pneumoniae Rx1

56.49

100

0.598
  cinA Streptococcus mitis NCTC 12261

56.25

100

0.595
  cinA Streptococcus pneumoniae D39

56.25

100

0.595
  cinA Bacillus subtilis subsp. subtilis str. 168

41.91

95.929

0.402

Multiple sequence alignment