Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   SDD27957_10890 Genome accession   CM001076
Coordinates   2073123..2074394 (-) Length   423 a.a.
NCBI ID   EFY03759.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. dysgalactiae ATCC 27957     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2068123..2079394
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SDD27957_10855 - 2068210..2069772 (-) 1563 EFY03752.1 hypothetical protein -
  SDD27957_10860 - 2069916..2070035 (-) 120 EFY03753.1 hypothetical protein -
  SDD27957_10865 - 2070118..2070423 (-) 306 EFY03754.1 hypothetical protein -
  SDD27957_10870 - 2070434..2070853 (-) 420 EFY03755.1 Holliday junction resolvase-like protein -
  SDD27957_10875 - 2070850..2071119 (-) 270 EFY03756.1 hypothetical protein -
  SDD27957_10880 spxA 2071231..2071629 (-) 399 EFY03757.1 transcriptional regulator Spx -
  SDD27957_10885 recA 2071928..2072947 (-) 1020 EFY03758.1 recombinase A Machinery gene
  SDD27957_10890 cinA 2073123..2074394 (-) 1272 EFY03759.1 competence damage-inducible protein A Machinery gene
  SDD27957_10895 - 2074518..2074856 (-) 339 EFY03760.1 hypothetical protein -
  SDD27957_10900 - 2075067..2075318 (-) 252 EFY03761.1 DNA-3-methyladenine glycosylase -
  SDD27957_10905 ruvA 2075457..2076050 (-) 594 EFY03762.1 Holliday junction DNA helicase RuvA -
  SDD27957_10910 - 2076052..2077272 (-) 1221 EFY03763.1 Putative integral membrane protein -
  SDD27957_10915 mutL 2077283..2079268 (-) 1986 EFY03764.1 DNA mismatch repair protein -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 45932.46 Da        Isoelectric Point: 4.7495

>NTDB_id=20061 SDD27957_10890 EFY03759.1 2073123..2074394(-) (cinA) [Streptococcus dysgalactiae subsp. dysgalactiae ATCC 27957]
MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLLSVIATASQRSDLVILCGGLGPTEDDLTKQT
LAKYLNRDLVFEEQASQKLDDFYASCKESSRTANNAKQAQIIAGSSPLQNRTGLAVGGLITVNKVTYVVLPGPPSELKPM
VNEELLPLLSTQSRKLYSRVLRFFGIGESQLVTVLSDLIENQTDPTIAPYAKTGEVTLRLSTKAESQTLADTKLDQLEAQ
LLSRKTPDNQSLSDFLYGYREDNSLAREVFELLVKYDKTITAAESLTAGLFQSTLASFPGASQVFNGGFVTYSMEEKAKM
LGIPLEDLTSYGVVSAYTAEKMAEQARLLTGADIGISLTGVAGPDMLENQPAGTVFIGLAIQNKVESMKVLIGGRSRSDV
RHIATLHAFNMVRKTLLKPENLL

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=20061 SDD27957_10890 EFY03759.1 2073123..2074394(-) (cinA) [Streptococcus dysgalactiae subsp. dysgalactiae ATCC 27957]
ATGAAAGCTGAACTGATTGCAGTAGGTACCGAAATTTTGACTGGTCAAATTGTGAATACTAATGCTCAATTTTTGTCGGA
AAAAATGGCAGAGCTAGGTATTGATGTCTATTTTCAAACGGCTGTTGGGGACAACGAGGAGCGTTTACTTTCAGTGATTG
CAACTGCTAGTCAGCGGAGTGATTTGGTCATTTTATGTGGTGGTCTTGGCCCCACGGAAGATGATTTAACCAAGCAGACT
TTAGCAAAATACCTTAATAGAGATTTGGTCTTTGAAGAACAAGCTAGTCAAAAATTAGACGATTTTTATGCCAGTTGTAA
AGAGTCGTCTCGAACGGCAAATAATGCTAAGCAGGCTCAAATCATTGCTGGTTCAAGCCCTCTGCAAAATAGAACAGGAC
TCGCAGTGGGGGGCTTAATCACTGTTAATAAGGTGACTTATGTTGTTTTACCAGGGCCGCCAAGTGAATTAAAACCTATG
GTTAATGAGGAACTGCTTCCTCTTTTGTCCACACAATCTCGCAAACTTTACTCGAGAGTCTTACGATTTTTTGGGATTGG
TGAGAGTCAGCTGGTGACGGTCTTATCAGACCTTATTGAGAATCAAACTGACCCTACCATTGCACCTTATGCCAAAACTG
GTGAAGTGACCCTTCGTTTATCAACGAAAGCTGAAAGTCAAACATTAGCAGATACGAAATTAGATCAACTAGAAGCGCAG
CTATTGTCGCGAAAAACTCCTGACAACCAGTCGTTATCAGATTTTCTTTATGGCTATAGAGAGGATAATTCCTTAGCGCG
TGAGGTATTTGAGCTCTTAGTAAAATATGATAAGACAATTACAGCAGCAGAAAGTCTAACCGCGGGATTATTTCAGTCAA
CTTTGGCGAGTTTTCCAGGAGCTTCTCAAGTATTCAATGGAGGCTTTGTGACTTATAGCATGGAAGAAAAAGCGAAAATG
CTAGGCATTCCTCTAGAGGATTTGACATCGTATGGAGTTGTTAGTGCTTATACGGCTGAGAAGATGGCGGAGCAAGCAAG
ATTATTGACTGGTGCTGATATTGGGATAAGTTTAACAGGTGTTGCCGGACCAGATATGTTGGAGAACCAGCCTGCAGGTA
CAGTTTTCATTGGTCTTGCCATTCAAAATAAGGTAGAATCAATGAAGGTTTTAATCGGGGGACGGAGCCGTTCAGATGTG
CGTCATATTGCGACTTTACATGCTTTTAATATGGTCCGTAAAACTTTATTAAAACCTGAAAATTTGCTATAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(263-416)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-243)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

72.34

100

0.723
  cinA Streptococcus mitis SK321

71.463

98.582

0.704
  cinA Streptococcus mitis NCTC 12261

70.264

98.582

0.693
  cinA Streptococcus pneumoniae TIGR4

69.544

98.582

0.686
  cinA Streptococcus pneumoniae Rx1

69.544

98.582

0.686
  cinA Streptococcus pneumoniae R6

69.544

98.582

0.686
  cinA Streptococcus pneumoniae D39

69.305

98.582

0.683
  cinA Streptococcus suis isolate S10

53.606

98.345

0.527
  cinA Bacillus subtilis subsp. subtilis str. 168

46.172

98.818

0.456

Multiple sequence alignment