Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   WH25_RS08740 Genome accession   NZ_CP017295
Coordinates   1820232..1820897 (-) Length   221 a.a.
NCBI ID   WP_046165270.1    Uniprot ID   -
Organism   Streptococcus gordonii strain IE35     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1815232..1825897
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WH25_RS08725 (WH25_08725) - 1816202..1816807 (-) 606 WP_045773124.1 superoxide dismutase -
  WH25_RS08730 (WH25_08730) holA 1816880..1817917 (-) 1038 WP_045773123.1 DNA polymerase III subunit delta -
  WH25_RS08735 (WH25_08735) comEC/celB 1818008..1820248 (-) 2241 WP_046165271.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  WH25_RS08740 (WH25_08740) comEA/celA/cilE 1820232..1820897 (-) 666 WP_046165270.1 helix-hairpin-helix domain-containing protein Machinery gene
  WH25_RS08745 (WH25_08745) - 1820994..1821521 (-) 528 WP_046165269.1 HXXEE domain-containing protein -
  WH25_RS08750 (WH25_08750) - 1821560..1822300 (-) 741 WP_046165938.1 lysophospholipid acyltransferase family protein -
  WH25_RS08755 (WH25_08755) - 1822430..1824799 (+) 2370 WP_046165268.1 cation-translocating P-type ATPase -
  WH25_RS08760 (WH25_08760) - 1824904..1825650 (+) 747 WP_046165267.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 23529.24 Da        Isoelectric Point: 4.9605

>NTDB_id=197428 WH25_RS08740 WP_046165270.1 1820232..1820897(-) (comEA/celA/cilE) [Streptococcus gordonii strain IE35]
MIEDLIEKAKQYKIALSLGLLGAIVAGFILLQGRDQGGTDVQQLTEQTSSSSSYKDEKSNKSNEISQAETGDQLVTVDVK
GAVKKPGVYQLQSNSRVHDALEKAGGMTEEADLKSVNQAQKLSDEAVVYVAKVGENTVDVTASAHTSATSGTGQTKSALV
NLNTATEADFQTISGIGQKRAQDIIAYREANGRFKSVDDLKNVSGIGAKTLEKLKEYVTVD

Nucleotide


Download         Length: 666 bp        

>NTDB_id=197428 WH25_RS08740 WP_046165270.1 1820232..1820897(-) (comEA/celA/cilE) [Streptococcus gordonii strain IE35]
ATGATAGAAGATTTGATAGAAAAAGCAAAGCAATATAAAATTGCTTTAAGTCTAGGCTTATTAGGAGCGATTGTAGCAGG
CTTTATTTTACTACAGGGAAGAGACCAAGGGGGGACAGATGTCCAGCAATTGACAGAGCAAACTTCTTCCTCTAGCTCAT
ATAAGGATGAAAAAAGTAACAAAAGCAATGAGATCAGTCAAGCCGAGACAGGAGATCAGTTGGTTACAGTTGATGTCAAG
GGTGCGGTAAAAAAGCCTGGTGTCTATCAGTTGCAGTCTAATAGTCGGGTTCATGATGCTTTAGAGAAGGCAGGTGGCAT
GACGGAAGAAGCTGACTTAAAATCCGTCAATCAGGCTCAGAAACTGAGCGATGAGGCGGTAGTATATGTGGCTAAAGTAG
GTGAAAATACTGTAGACGTTACAGCAAGTGCCCATACAAGTGCAACATCGGGCACCGGTCAGACAAAATCAGCACTTGTC
AATCTTAATACAGCAACAGAAGCAGACTTTCAAACCATTTCTGGTATCGGACAAAAACGTGCTCAGGATATTATTGCTTA
CCGAGAAGCCAATGGCAGATTTAAGTCTGTAGATGATCTGAAAAATGTATCAGGTATTGGGGCCAAAACTCTAGAAAAAT
TAAAAGAATATGTCACAGTGGATTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(77-130)

Helix-hairpin-helix motif (HHH_3)

(158-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae D39

50.45

100

0.507
  comEA/celA/cilE Streptococcus pneumoniae R6

50.45

100

0.507
  comEA/celA/cilE Streptococcus mitis NCTC 12261

50.45

100

0.507
  comEA/celA/cilE Streptococcus pneumoniae Rx1

50.45

100

0.507
  comEA/celA/cilE Streptococcus mitis SK321

50

100

0.502
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

50

100

0.502
  comEA Streptococcus thermophilus LMD-9

58.784

66.968

0.394
  comEA Bacillus subtilis subsp. subtilis str. 168

40.758

95.475

0.389
  comEA Latilactobacillus sakei subsp. sakei 23K

35.27

100

0.385

Multiple sequence alignment