Detailed information NTG0197427

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: WH25_RS08735
• Genome accession: NZ_CP017295
• Coordinates: 1818008..1820248 (-)
• Length: 746 a.a.
• NCBI ID: WP_046165271.1
• Uniprot ID: -
• Organism: Streptococcus gordonii strain IE35
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1813008..1825248

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WH25_RS08705 (WH25_08705)	-	1813280..1813777 (-)	498	WP_046165273.1	DUF1648 domain-containing protein	-
WH25_RS08710 (WH25_08710)	-	1813764..1814045 (-)	282	WP_012130660.1	autorepressor SdpR family transcription factor	-
WH25_RS08715 (WH25_08715)	-	1814023..1814811 (-)	789	WP_046165272.1	YhfC family intramembrane metalloprotease	-
WH25_RS08720 (WH25_08720)	-	1815017..1816090 (-)	1074	WP_125443582.1	serine hydrolase	-
WH25_RS08725 (WH25_08725)	-	1816202..1816807 (-)	606	WP_045773124.1	superoxide dismutase	-
WH25_RS08730 (WH25_08730)	holA	1816880..1817917 (-)	1038	WP_045773123.1	DNA polymerase III subunit delta	-
WH25_RS08735 (WH25_08735)	comEC/celB	1818008..1820248 (-)	2241	WP_046165271.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
WH25_RS08740 (WH25_08740)	comEA/celA/cilE	1820232..1820897 (-)	666	WP_046165270.1	helix-hairpin-helix domain-containing protein	Machinery gene
WH25_RS08745 (WH25_08745)	-	1820994..1821521 (-)	528	WP_046165269.1	HXXEE domain-containing protein	-
WH25_RS08750 (WH25_08750)	-	1821560..1822300 (-)	741	WP_046165938.1	lysophospholipid acyltransferase family protein	-
WH25_RS08755 (WH25_08755)	-	1822430..1824799 (+)	2370	WP_046165268.1	cation-translocating P-type ATPase	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 85434.32 Da
• Isoelectric Point: 9.7431

>NTDB_id=197427 WH25_RS08735 WP_046165271.1 1818008..1820248(-) (comEC/celB) [Streptococcus gordonii strain IE35]
MSQWIKKLPLAPIYLCFLLVWLYFAIYSGERLAYLGFSLLIARLIWHYPRKKWLPTLAILIAFSIFFYARRELTEQAFQT
QPAPARQVLVLPDTVKVNGDSLSFRGRIDGRLYQLYYKLASPREKKSFQKLADLVTLEIEAEFNLAEGRRNFSGFDYQAY
LKSQGIYRTVKISRIMSSHSGQSINPFDWLSVWRRKALVFIKTTFPSPMSHYMTGLLFGDLDIEFAEMNDLYSSLGIIHL
FALSGMQVGFFMDAFRKILLRIGLRMETVDWLQFPLSFVYAGLTGFSVSVVRSLVQKLLSQFGVRHLDNFAMTIMTLMFL
MPSFLLTTGGVLSCAYAFIITMLDFEDFSSFRKAVLESLSISLGILPILIYYFAEFQPWSILLTFLFSIVFDTFMLPLLS
LIFLISPLFAFTQVNIFFQWLEMVIRWVASLSTRPIILGQPNLPLLIILLLVLALLYDFRKQKKIRVCLSLLAILLFFLS
KHPLQNEITVVDIGQGDSIFLRDISGRTIVIDAGGRVEIGKKEAWQERVRKSNAETTLIPYLKSRGVDRLDKLVLTHTDT
DHMGDMLELAKHFSIREIYVSKGSMTQADFVDKLKKMKAKVHVVEVGDRLPIFDSALEVLYPLGQGDGGNDDSIVLYGEF
FQTKFLFTGDLEAPGEGQMVTAYPDLRVDVLKAGHHGSKGSSSPEFLEHIKPKLALISAGKNNRYQHPHKETLDRFEKIQ
TKILRTDERGAIRFKGWNSWKIETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=197427 WH25_RS08735 WP_046165271.1 1818008..1820248(-) (comEC/celB) [Streptococcus gordonii strain IE35]
ATGTCACAGTGGATTAAAAAACTTCCCCTTGCTCCAATCTACTTGTGCTTTCTTTTGGTTTGGCTATACTTTGCTATTTA
TAGTGGTGAAAGGCTCGCTTATCTAGGTTTTTCCCTGCTTATAGCTCGCCTAATCTGGCATTATCCAAGAAAGAAATGGT
TGCCAACTTTAGCTATTCTAATTGCTTTCTCTATCTTTTTTTATGCTAGACGTGAGTTGACGGAACAAGCTTTTCAGACT
CAACCAGCTCCAGCAAGACAAGTTCTTGTTTTACCAGATACTGTTAAAGTGAATGGAGATTCCCTATCTTTCCGTGGTAG
AATAGACGGAAGACTTTATCAGCTCTACTACAAATTAGCAAGTCCAAGAGAGAAAAAATCATTTCAGAAACTAGCAGACT
TGGTCACTTTAGAAATAGAAGCAGAGTTTAATCTAGCAGAAGGTCGGCGAAATTTTTCTGGTTTTGACTATCAGGCTTAT
TTAAAAAGTCAGGGAATATATCGGACAGTTAAGATCAGTAGGATTATGTCCAGTCACTCTGGTCAATCTATCAATCCATT
TGATTGGCTGTCTGTTTGGCGTAGGAAGGCCTTGGTTTTCATTAAGACTACGTTTCCAAGTCCAATGAGTCACTACATGA
CAGGACTCTTGTTTGGTGATTTGGATATTGAATTTGCAGAGATGAATGACTTGTACTCAAGTTTAGGAATTATCCATCTT
TTTGCTTTATCAGGAATGCAGGTTGGCTTTTTTATGGATGCCTTTCGGAAAATTCTTTTGCGCATAGGCTTAAGGATGGA
AACGGTAGATTGGTTGCAATTCCCGTTGTCCTTTGTTTATGCAGGTTTGACTGGATTTTCTGTGTCAGTAGTGAGGAGTT
TAGTGCAAAAATTATTGTCTCAATTTGGAGTGAGGCACTTGGATAATTTTGCGATGACCATAATGACCTTGATGTTTCTT
ATGCCGAGTTTTCTCCTGACAACAGGCGGAGTCCTATCTTGCGCTTATGCCTTTATCATCACTATGTTGGATTTTGAGGA
TTTTAGTAGCTTTCGTAAAGCCGTGCTAGAGAGTTTAAGTATCTCGTTAGGCATTTTACCGATTCTTATCTACTATTTTG
CAGAATTCCAACCTTGGTCTATCCTCTTGACCTTCCTTTTTTCAATCGTCTTTGATACATTTATGTTGCCTCTCTTGAGT
CTGATTTTTCTCATTTCGCCTTTGTTTGCCTTCACTCAAGTTAACATCTTCTTCCAATGGCTGGAAATGGTGATTCGCTG
GGTAGCTAGTTTGTCAACAAGGCCGATAATTTTAGGACAGCCAAATCTACCTTTGCTTATTATTCTCCTACTAGTCTTAG
CCCTGCTCTATGACTTTAGAAAACAAAAAAAGATTAGGGTTTGTCTGAGTCTCTTAGCAATCTTACTATTTTTCCTAAGT
AAACATCCCTTACAAAATGAAATCACAGTAGTTGATATTGGGCAGGGAGACAGTATATTTCTGAGAGATATTAGTGGCCG
AACCATTGTAATTGATGCAGGGGGGCGGGTGGAGATTGGTAAAAAAGAGGCTTGGCAAGAACGAGTTAGAAAAAGCAATG
CGGAAACGACCTTAATCCCTTATCTAAAAAGCCGAGGAGTGGATCGATTGGATAAATTGGTCTTGACTCACACCGATACA
GACCATATGGGAGATATGTTGGAGTTAGCTAAGCACTTTTCTATCCGAGAAATTTATGTTTCCAAAGGAAGTATGACTCA
AGCTGATTTTGTAGACAAGTTAAAGAAGATGAAAGCTAAAGTTCATGTGGTCGAGGTAGGAGATCGGCTTCCTATTTTTG
ATTCTGCCCTTGAAGTGCTCTATCCACTCGGTCAAGGAGATGGTGGTAATGATGACTCGATTGTCTTGTATGGTGAATTT
TTCCAAACAAAGTTTCTTTTCACAGGAGATTTAGAAGCTCCAGGTGAAGGTCAGATGGTGACAGCCTATCCAGATTTAAG
AGTAGATGTGCTCAAAGCTGGGCATCATGGTTCTAAAGGATCTTCTAGTCCAGAATTTCTAGAGCATATTAAGCCTAAGT
TGGCCTTGATTTCAGCTGGTAAAAACAACCGTTACCAACATCCGCATAAGGAAACTTTAGATAGATTCGAAAAAATCCAG
ACCAAGATTTTACGAACAGATGAGCGGGGTGCTATTCGATTTAAAGGCTGGAATTCTTGGAAGATAGAAACGGTTCGTTA
G

Domains

Predicted by InterproScan.

• Competence protein (Competence) (216-460)

• Metallo-beta-lactamase superfamily (Lactamase_B) (494-700)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	57.697	100	0.578
comEC/celB	Streptococcus mitis NCTC 12261	57.239	100	0.572
comEC/celB	Streptococcus pneumoniae TIGR4	56.627	100	0.567
comEC/celB	Streptococcus pneumoniae Rx1	56.359	100	0.564
comEC/celB	Streptococcus pneumoniae D39	56.359	100	0.564
comEC/celB	Streptococcus pneumoniae R6	56.359	100	0.564
comEC	Lactococcus lactis subsp. cremoris KW2	49.059	99.732	0.489