Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   FAM18149p_RS02775 Genome accession   NZ_CP017261
Coordinates   511129..512370 (+) Length   413 a.a.
NCBI ID   WP_016386175.1    Uniprot ID   -
Organism   Lacticaseibacillus paracasei strain FAM18149     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 495541..537236 511129..512370 within 0


Gene organization within MGE regions


Location: 495541..537236
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FAM18149p_RS02690 (FAM18149p_02540) - 495541..496539 (-) 999 WP_016377049.1 IS30 family transposase -
  FAM18149p_RS02700 (FAM18149p_02545) - 496745..497785 (-) 1041 WP_096836061.1 lactonase family protein -
  FAM18149p_RS02705 (FAM18149p_02550) - 498057..498434 (+) 378 WP_003564152.1 PTS glucitol/sorbitol transporter subunit IIA -
  FAM18149p_RS02710 (FAM18149p_02555) rpsN 498546..498815 (-) 270 WP_003564153.1 30S ribosomal protein S14 -
  FAM18149p_RS02715 (FAM18149p_02560) - 498943..499920 (-) 978 WP_032674946.1 GMP reductase -
  FAM18149p_RS02720 (FAM18149p_02565) - 500160..501107 (-) 948 WP_003564155.1 magnesium transporter CorA family protein -
  FAM18149p_RS02725 (FAM18149p_02570) - 501173..502015 (+) 843 WP_096836063.1 methyltransferase domain-containing protein -
  FAM18149p_RS02735 (FAM18149p_02575) trmL 502270..502779 (+) 510 WP_003601708.1 tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL -
  FAM18149p_RS02740 (FAM18149p_02580) - 502906..503316 (+) 411 WP_003564159.1 DUF1149 family protein -
  FAM18149p_RS02745 (FAM18149p_02585) - 503489..505810 (+) 2322 WP_003601713.1 FtsK/SpoIIIE family DNA translocase -
  FAM18149p_RS02750 (FAM18149p_02590) yfmF 505819..507081 (+) 1263 WP_003601715.1 EF-P 5-aminopentanol modification-associated protein YfmF -
  FAM18149p_RS02755 (FAM18149p_02595) yfmH 507078..508370 (+) 1293 WP_003601717.1 EF-P 5-aminopentanol modification-associated protein YfmH -
  FAM18149p_RS02760 (FAM18149p_02600) ymfI 508370..509098 (+) 729 WP_003601719.1 elongation factor P 5-aminopentanone reductase -
  FAM18149p_RS02765 (FAM18149p_02605) - 509185..510123 (+) 939 WP_003601721.1 helix-turn-helix domain-containing protein -
  FAM18149p_RS02770 (FAM18149p_02610) pgsA 510120..510713 (+) 594 WP_003564171.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  FAM18149p_RS02775 (FAM18149p_02615) cinA 511129..512370 (+) 1242 WP_016386175.1 competence/damage-inducible protein A Machinery gene
  FAM18149p_RS02780 (FAM18149p_02620) recA 512427..513488 (+) 1062 WP_016386176.1 recombinase RecA Machinery gene
  FAM18149p_RS02785 - 513725..515002 (+) 1278 WP_016386172.1 ISL3 family transposase -
  FAM18149p_RS02790 (FAM18149p_02630) rny 515285..516856 (+) 1572 WP_003657913.1 ribonuclease Y -
  FAM18149p_RS02795 (FAM18149p_02635) - 516950..517600 (-) 651 WP_003601729.1 YigZ family protein -
  FAM18149p_RS02800 (FAM18149p_02640) - 517628..518890 (+) 1263 WP_003601731.1 helicase-related protein -
  FAM18149p_RS02805 (FAM18149p_02645) - 519103..519564 (+) 462 WP_016378308.1 ComF family protein -
  FAM18149p_RS02810 (FAM18149p_02650) hpf 519688..520245 (+) 558 WP_003601735.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  FAM18149p_RS02820 (FAM18149p_02655) secA 520579..522942 (+) 2364 WP_003578257.1 preprotein translocase subunit SecA -
  FAM18149p_RS02825 (FAM18149p_02660) prfB 523067..524183 (+) 1117 WP_096836065.1 peptide chain release factor 2 -
  FAM18149p_RS02830 (FAM18149p_02665) ftsE 524260..524946 (+) 687 WP_096836067.1 cell division ATP-binding protein FtsE -
  FAM18149p_RS02835 (FAM18149p_02670) ftsX 524936..525823 (+) 888 WP_003564193.1 permease-like cell division protein FtsX -
  FAM18149p_RS02840 (FAM18149p_02675) - 525984..527087 (+) 1104 WP_016386165.1 PDZ domain-containing protein -
  FAM18149p_RS02845 (FAM18149p_02680) - 527084..527791 (+) 708 WP_003564199.1 response regulator transcription factor -
  FAM18149p_RS02850 (FAM18149p_02685) pnpS 527784..529451 (+) 1668 WP_003601738.1 two-component system histidine kinase PnpS -
  FAM18149p_RS02855 (FAM18149p_02690) - 529554..530414 (+) 861 WP_003601739.1 phosphate ABC transporter substrate-binding protein PstS family protein -
  FAM18149p_RS02860 (FAM18149p_02695) pstC 530555..531478 (+) 924 WP_003564205.1 phosphate ABC transporter permease subunit PstC -
  FAM18149p_RS02865 (FAM18149p_02700) pstA 531475..532359 (+) 885 WP_003564208.1 phosphate ABC transporter permease PstA -
  FAM18149p_RS02870 (FAM18149p_02705) pstB 532439..533257 (+) 819 WP_003564210.1 phosphate ABC transporter ATP-binding protein PstB -
  FAM18149p_RS02875 (FAM18149p_02710) pstB 533267..534031 (+) 765 WP_003564212.1 phosphate ABC transporter ATP-binding protein PstB -
  FAM18149p_RS02880 (FAM18149p_02715) phoU 534042..534719 (+) 678 WP_003569545.1 phosphate signaling complex protein PhoU -
  FAM18149p_RS02885 (FAM18149p_02720) liaX 535139..536620 (+) 1482 WP_003564216.1 daptomycin-sensing surface protein LiaX -
  FAM18149p_RS02890 (FAM18149p_02725) - 536632..536901 (+) 270 WP_003601740.1 hypothetical protein -
  FAM18149p_RS02895 (FAM18149p_02730) - 536901..537236 (+) 336 WP_003564220.1 phage holin family protein -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 44325.66 Da        Isoelectric Point: 6.0028

>NTDB_id=197055 FAM18149p_RS02775 WP_016386175.1 511129..512370(+) (cinA) [Lacticaseibacillus paracasei strain FAM18149]
MQAEIIAVGTEILMGQITNTNGAYMAKQLTALGIDSYHQQVVGDNGPRLEEAIKLAESRSNLVILIGGLGPTPDDLTKQT
LAAHLNRKLVEDPDAMAKLQARVKQQQRPMTPNNQLQAMYPEGADILVNRVGLAVGAWIVNGQHTYVLLPGPPKEFVPMV
DHELLPRLAKWNGHAEVMVSRVLRFFGIGESQLVTDLDDLIANQTDPTIATYIKDHEVTVRVTASGATEKDADAKLEPMV
GAIMDRDGQYFYGYGDDNSLAKELVKTLAANDMQITAAESLTAGAFQAALGDVPGVSTYFKGGFVTYSLATKAAFLAIDA
RELAAHGVVSAFTAKAMAEHARRKAAADISVSFTGVAGPDTLEGQPAGTVWIGLARRGQLPEAHVYHFPGGRNDVRQRAV
MTGMMLALRALQA

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=197055 FAM18149p_RS02775 WP_016386175.1 511129..512370(+) (cinA) [Lacticaseibacillus paracasei strain FAM18149]
ATGCAAGCAGAGATTATTGCTGTCGGGACAGAGATCCTGATGGGACAGATTACTAACACAAATGGTGCCTATATGGCTAA
GCAACTGACAGCACTGGGTATTGATAGCTACCATCAACAGGTGGTGGGAGACAACGGTCCGCGACTTGAGGAGGCCATTA
AGTTGGCGGAAAGTCGCAGTAATTTAGTTATTTTGATTGGCGGGTTAGGACCGACACCAGATGATCTGACCAAGCAAACA
TTGGCAGCGCACTTGAACCGCAAATTGGTTGAAGATCCTGACGCTATGGCTAAACTACAGGCGCGCGTCAAGCAACAGCA
GCGGCCAATGACGCCTAATAATCAATTACAGGCCATGTATCCGGAAGGCGCCGATATTTTGGTCAATCGGGTTGGCTTAG
CGGTTGGCGCGTGGATCGTCAATGGGCAGCACACCTATGTCTTATTGCCGGGACCACCGAAGGAATTCGTTCCGATGGTT
GATCATGAACTGCTGCCGCGGCTAGCAAAATGGAACGGCCACGCGGAAGTTATGGTCAGCCGGGTCTTACGTTTCTTTGG
CATTGGCGAATCGCAACTAGTGACAGATCTGGACGACTTGATTGCCAACCAAACCGATCCGACCATTGCAACTTATATCA
AGGATCATGAGGTGACGGTGCGCGTCACTGCCAGTGGCGCTACCGAAAAAGACGCTGATGCAAAGTTAGAACCAATGGTC
GGTGCAATCATGGATCGTGATGGTCAATATTTTTACGGCTACGGTGACGACAATAGTTTGGCAAAAGAGCTTGTGAAGAC
GCTTGCGGCAAATGATATGCAAATTACTGCAGCTGAGAGTTTGACTGCCGGCGCATTTCAAGCAGCGTTAGGCGATGTGC
CGGGGGTATCGACTTATTTTAAGGGCGGTTTTGTCACTTACTCACTTGCAACAAAGGCCGCTTTTTTGGCAATTGATGCT
CGCGAATTAGCGGCACACGGAGTTGTCAGCGCATTTACAGCCAAGGCGATGGCTGAACATGCTCGGCGTAAGGCAGCTGC
GGATATAAGTGTCAGCTTTACCGGCGTTGCCGGTCCAGACACGCTGGAAGGACAGCCTGCTGGTACGGTTTGGATCGGTT
TAGCGCGGCGCGGCCAACTGCCTGAAGCACATGTTTACCATTTTCCTGGCGGTCGCAATGATGTTCGGCAGCGTGCTGTG
ATGACTGGTATGATGCTTGCATTAAGGGCGCTGCAGGCCTAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Competence-damaged protein (CinA)

(258-410)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis NCTC 12261

51.651

100

0.53
  cinA Streptococcus mitis SK321

51.537

100

0.528
  cinA Streptococcus pneumoniae TIGR4

51.179

100

0.525
  cinA Streptococcus pneumoniae R6

50.708

100

0.521
  cinA Streptococcus pneumoniae Rx1

50.708

100

0.521
  cinA Streptococcus mutans UA159

51.932

100

0.521
  cinA Streptococcus pneumoniae D39

50.472

100

0.518
  cinA Bacillus subtilis subsp. subtilis str. 168

45.012

99.516

0.448
  cinA Streptococcus suis isolate S10

42.063

91.525

0.385

Multiple sequence alignment