Detailed information NTG0196557

Bioinformatically predicted

Overview

• Name: comGC/cglC
• Type: Machinery gene
• Locus tag: BHS01_RS01055
• Genome accession: NZ_CP017195
• Coordinates: 208479..208826 (+)
• Length: 115 a.a.
• NCBI ID: WP_109833907.1
• Uniprot ID: A0A7L4WA75
• Organism: Lactococcus paracarnosus strain TMW 2.1615
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 203479..213826

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BHS01_RS01045 (BHS01_01035)	comGA/cglA/cilD	206568..207509 (+)	942	WP_191246366.1	competence type IV pilus ATPase ComGA	Machinery gene
BHS01_RS01050 (BHS01_01040)	comGB	207451..208476 (+)	1026	WP_162542379.1	competence type IV pilus assembly protein ComGB	-
BHS01_RS01055 (BHS01_01045)	comGC/cglC	208479..208826 (+)	348	WP_109833907.1	competence type IV pilus major pilin ComGC	Machinery gene
BHS01_RS01060 (BHS01_01050)	comGD	208798..209226 (+)	429	WP_162542380.1	competence type IV pilus minor pilin ComGD	-
BHS01_RS01065 (BHS01_01055)	comGE	209198..209503 (+)	306	WP_162542381.1	competence type IV pilus minor pilin ComGE	-
BHS01_RS01070 (BHS01_01060)	comGF	209478..209921 (+)	444	WP_223271025.1	competence type IV pilus minor pilin ComGF	-
BHS01_RS01075 (BHS01_01065)	comGG	209933..210217 (+)	285	WP_109833910.1	competence type IV pilus minor pilin ComGG	-
BHS01_RS01080 (BHS01_01070)	-	210427..210846 (+)	420	WP_109833911.1	GNAT family N-acetyltransferase	-
BHS01_RS01085 (BHS01_01075)	ispE	210942..211793 (+)	852	WP_109833912.1	4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase	-
BHS01_RS01090 (BHS01_01080)	-	211922..212371 (+)	450	WP_109833913.1	zinc-dependent MarR family transcriptional regulator	-
BHS01_RS01095 (BHS01_01085)	-	212371..213114 (+)	744	WP_109833914.1	metal ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 115 a.a.
• Molecular weight: 13129.60 Da
• Isoelectric Point: 9.6950

>NTDB_id=196557 BHS01_RS01055 WP_109833907.1 208479..208826(+) (comGC/cglC) [Lactococcus paracarnosus strain TMW 2.1615]
MRVRKWEEKRMMHKKMVAAFTLLEMLIVLMIISILILLFVPNLSSQKTTIKETGNAAVVKVIMSQAELYQLNHSGKVSLK
ILLEDGNITQQQVDAYHAYYALAKNKGEKPEIPED

Nucleotide

• Length: 348 bp

>NTDB_id=196557 BHS01_RS01055 WP_109833907.1 208479..208826(+) (comGC/cglC) [Lactococcus paracarnosus strain TMW 2.1615]
ATGAGGGTTAGAAAATGGGAGGAAAAAAGGATGATGCATAAAAAAATGGTAGCTGCTTTTACTTTACTAGAGATGTTGAT
TGTTTTGATGATCATCAGTATCCTCATCTTGTTATTTGTCCCCAATTTATCATCTCAAAAGACGACGATTAAGGAGACTG
GTAATGCTGCTGTGGTTAAAGTGATTATGTCTCAGGCAGAATTATACCAGCTTAATCATTCGGGAAAAGTATCTTTGAAA
ATCTTACTAGAAGACGGTAATATCACACAACAACAGGTGGACGCGTATCATGCTTATTATGCACTGGCTAAAAACAAGGG
TGAGAAACCAGAAATTCCGGAGGATTAG

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (16-38)

3D structure

• AlphaFold DB: A0A7L4WA75

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC	Lactococcus lactis subsp. cremoris KW2	58.163	85.217	0.496
comGC/cglC	Streptococcus mitis SK321	55.882	88.696	0.496
comYC	Streptococcus gordonii str. Challis substr. CH1	54.369	89.565	0.487
comGC/cglC	Streptococcus pneumoniae R6	50.459	94.783	0.478
comGC/cglC	Streptococcus pneumoniae D39	50.459	94.783	0.478
comGC/cglC	Streptococcus pneumoniae Rx1	50.459	94.783	0.478
comGC/cglC	Streptococcus mitis NCTC 12261	55.208	83.478	0.461
comGC/cglC	Streptococcus pneumoniae TIGR4	55.319	81.739	0.452
comYC	Streptococcus mutans UA140	60	73.913	0.443
comYC	Streptococcus mutans UA159	60	73.913	0.443
comYC	Streptococcus suis isolate S10	55	69.565	0.383