Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   A7J08_RS00405 Genome accession   NZ_CP017088
Coordinates   71902..73083 (+) Length   393 a.a.
NCBI ID   WP_148115621.1    Uniprot ID   A0A3Q8C001
Organism   Streptococcus suis strain SRD478     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 66902..78083
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A7J08_RS00385 (A7J08_00390) - 67078..68601 (+) 1524 WP_053866699.1 quinol oxidase -
  A7J08_RS00390 (A7J08_00395) mutL 68719..70656 (+) 1938 WP_053866700.1 DNA mismatch repair endonuclease MutL -
  A7J08_RS00395 (A7J08_00400) ruvA 70695..71285 (+) 591 WP_053866701.1 Holliday junction branch migration protein RuvA -
  A7J08_RS00400 (A7J08_00405) - 71296..71865 (+) 570 WP_053866702.1 DNA-3-methyladenine glycosylase I -
  A7J08_RS00405 (A7J08_00410) cinA 71902..73083 (+) 1182 WP_148115621.1 competence/damage-inducible protein A Machinery gene
  A7J08_RS00410 (A7J08_00415) recA 73135..74286 (+) 1152 WP_011922545.1 recombinase RecA Machinery gene
  A7J08_RS00415 (A7J08_00420) spx 74522..74920 (+) 399 WP_002939362.1 transcriptional regulator Spx -
  A7J08_RS00420 (A7J08_00425) - 75020..75286 (+) 267 WP_002939360.1 IreB family regulatory phosphoprotein -
  A7J08_RS00425 (A7J08_00430) ruvX 75286..75705 (+) 420 WP_002939356.1 Holliday junction resolvase RuvX -
  A7J08_RS00430 (A7J08_00435) - 75717..76037 (+) 321 WP_002939343.1 DUF1292 domain-containing protein -
  A7J08_RS00435 (A7J08_00440) rpsJ 76471..76779 (+) 309 WP_002939332.1 30S ribosomal protein S10 -
  A7J08_RS00440 (A7J08_00445) rplC 76851..77477 (+) 627 WP_011921686.1 50S ribosomal protein L3 -

Sequence

Protein


Download         Length: 393 a.a.        Molecular weight: 42964.05 Da        Isoelectric Point: 4.4970

>NTDB_id=195373 A7J08_RS00405 WP_148115621.1 71902..73083(+) (cinA) [Streptococcus suis strain SRD478]
MKAELIAVGTEILTGQIVNTNAQFLSEKCAELGIDVYFHTAVGDNENRLLSVLEVACQRSDLVILCGGLGPTEDDLTKQT
LATFLGRKLVFDEKAIAKLDRFFASRPGRVRTPNNERQAQIVEGSQALQNPAGLAVGGMIEQDGVTYIVLPGPPSELKAM
FSENLLPLLSQSRQQLYSRVLRFFGIGESQLVTVLADLIDKQTDPTLAPYAKVGEVTLRLSTKATSQEEANLRLNQLEEE
ILQHDKLADYFYAYGEDNSLVKMVASCLIEKKQTIAIVEQGTGGLLQAELSLALADQPYFSGGKVIGQLGTESGRLSEEA
DCIRQELQADLGLAVSVLIKPESTEDNVLAKVYLTLATTSGISKKEIDLGGYSWQYLRQLACLQAWDFVRNTL

Nucleotide


Download         Length: 1182 bp        

>NTDB_id=195373 A7J08_RS00405 WP_148115621.1 71902..73083(+) (cinA) [Streptococcus suis strain SRD478]
ATGAAAGCAGAACTAATCGCCGTTGGGACGGAGATTTTGACAGGCCAAATCGTTAATACCAATGCTCAGTTCCTTTCGGA
GAAATGTGCAGAGCTGGGAATTGATGTTTATTTCCACACAGCTGTTGGAGATAATGAAAACAGGCTTCTGTCTGTACTGG
AAGTAGCCTGTCAGCGGAGCGACTTGGTCATTCTCTGTGGAGGACTTGGTCCAACTGAGGATGACTTGACCAAGCAGACC
CTGGCGACCTTCTTAGGTAGAAAATTGGTCTTTGATGAAAAGGCTATAGCAAAATTAGACCGCTTCTTTGCCAGTCGCCC
AGGTCGTGTCCGTACACCAAATAATGAACGCCAGGCACAGATTGTGGAGGGAAGTCAGGCGCTACAGAATCCAGCTGGTT
TAGCTGTTGGTGGTATGATTGAGCAAGATGGGGTGACCTATATTGTTTTGCCTGGCCCACCAAGTGAGCTCAAGGCCATG
TTTTCTGAGAATCTCTTACCTTTACTGTCCCAATCTCGGCAGCAACTTTATTCGCGTGTCCTACGCTTTTTTGGCATTGG
TGAAAGCCAGTTGGTGACTGTTTTGGCGGACTTGATTGACAAGCAGACAGACCCAACTCTTGCACCCTATGCTAAGGTTG
GAGAGGTGACTTTACGCTTGTCCACCAAAGCGACCAGCCAAGAAGAAGCAAATCTACGTTTGAATCAGTTGGAAGAAGAA
ATCTTACAACATGACAAACTGGCAGACTATTTCTATGCCTACGGAGAGGACAATAGTTTGGTCAAAATGGTAGCGTCTTG
TTTGATAGAGAAAAAACAAACTATAGCCATCGTCGAACAGGGGACAGGTGGTCTCTTGCAGGCTGAATTGAGTCTGGCTT
TGGCTGATCAGCCGTATTTTAGCGGAGGGAAAGTCATCGGTCAGCTAGGGACAGAATCGGGCAGGCTATCAGAGGAAGCT
GACTGCATTCGGCAGGAGCTGCAAGCTGATTTAGGTTTGGCTGTGTCTGTGCTTATCAAACCGGAATCAACAGAGGACAA
CGTACTTGCAAAAGTATATCTCACTTTGGCTACGACCTCGGGTATTTCCAAAAAAGAGATAGATTTAGGTGGTTATTCGT
GGCAATACCTTCGCCAGCTTGCTTGTTTGCAGGCCTGGGATTTTGTACGAAACACTTTGTGA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Competence-damaged protein (CinA)

(258-392)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3Q8C001

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus suis isolate S10

93.639

100

0.936
  cinA Streptococcus mutans UA159

57.178

100

0.598
  cinA Streptococcus pneumoniae R6

56.25

100

0.595
  cinA Streptococcus mitis SK321

56.25

100

0.595
  cinA Streptococcus pneumoniae TIGR4

56.25

100

0.595
  cinA Streptococcus pneumoniae Rx1

56.25

100

0.595
  cinA Streptococcus mitis NCTC 12261

56.01

100

0.593
  cinA Streptococcus pneumoniae D39

56.01

100

0.593
  cinA Bacillus subtilis subsp. subtilis str. 168

41.176

99.491

0.41

Multiple sequence alignment