Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   BFM96_RS06445 Genome accession   NZ_CP016953
Coordinates   1388573..1389238 (+) Length   221 a.a.
NCBI ID   WP_068991861.1    Uniprot ID   A0A917A6B7
Organism   Streptococcus himalayensis strain HTS2     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1383573..1394238
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BFM96_RS06420 secG 1383760..1383993 (+) 234 WP_068991842.1 preprotein translocase subunit SecG -
  BFM96_RS06425 rnr 1384174..1386459 (+) 2286 WP_068991845.1 ribonuclease R -
  BFM96_RS06430 smpB 1386422..1386889 (+) 468 WP_068991851.1 SsrA-binding protein SmpB -
  BFM96_RS06435 - 1386899..1387492 (+) 594 WP_068991856.1 DUF4230 domain-containing protein -
  BFM96_RS06440 - 1387715..1388446 (+) 732 WP_145939718.1 hypothetical protein -
  BFM96_RS06445 comEA/celA/cilE 1388573..1389238 (+) 666 WP_068991861.1 helix-hairpin-helix domain-containing protein Machinery gene
  BFM96_RS06450 comEC/celB 1389222..1391462 (+) 2241 WP_068991864.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  BFM96_RS06455 - 1392305..1392889 (+) 585 WP_068991866.1 GDSL-type esterase/lipase family protein -
  BFM96_RS06460 - 1392929..1393582 (+) 654 WP_068991869.1 uracil-DNA glycosylase -
  BFM96_RS06465 - 1393591..1394055 (+) 465 WP_068991872.1 8-oxo-dGTP diphosphatase -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 23511.59 Da        Isoelectric Point: 4.5381

>NTDB_id=194046 BFM96_RS06445 WP_068991861.1 1388573..1389238(+) (comEA/celA/cilE) [Streptococcus himalayensis strain HTS2]
MEKIMETIKEYKIVAAFVCLGVAIGGFFLFQTPTESSSSAQSLAQEVLVSSEEPKKETEEMVKAEPVEEPTLLTVDVKGA
VQHPGIYELKKESRVNDAIQAAGGLTAEAESKSVNLAQKLTDEAVIYVAKLGEEAPVVTTQAQVGNSQATGASSDASGKV
NLNTADLATLQTISGIGQKRAQDILDYRESNGKFKSVEELKNVSGIGAKTLEKLKAYVTVD

Nucleotide


Download         Length: 666 bp        

>NTDB_id=194046 BFM96_RS06445 WP_068991861.1 1388573..1389238(+) (comEA/celA/cilE) [Streptococcus himalayensis strain HTS2]
ATGGAAAAGATCATGGAAACCATAAAAGAATACAAGATTGTTGCAGCATTTGTCTGTTTAGGGGTGGCGATTGGGGGATT
TTTCCTCTTCCAAACGCCGACAGAAAGTAGCTCTAGTGCTCAGAGTCTGGCTCAAGAAGTCTTGGTCTCCTCAGAAGAGC
CAAAAAAAGAAACAGAGGAGATGGTCAAAGCGGAGCCTGTTGAAGAACCAACGCTACTGACTGTGGATGTCAAGGGAGCT
GTTCAACATCCTGGTATTTATGAGTTGAAAAAGGAGAGTCGGGTCAACGATGCGATTCAAGCAGCTGGTGGGTTGACCGC
AGAGGCTGAGAGCAAGTCCGTCAATCTTGCACAAAAGTTAACTGATGAAGCAGTGATTTATGTGGCAAAGCTTGGAGAGG
AAGCACCAGTTGTGACCACTCAAGCTCAAGTAGGGAATAGCCAAGCAACTGGAGCTAGCTCAGATGCATCTGGCAAGGTC
AATCTTAATACAGCTGACTTAGCGACCCTACAAACCATTTCAGGAATTGGACAAAAGCGTGCCCAGGATATTTTAGACTA
TCGTGAAAGCAATGGCAAATTCAAATCTGTGGAAGAGTTGAAAAATGTTTCTGGCATTGGGGCAAAGACCCTAGAAAAAT
TAAAGGCCTATGTTACAGTGGATTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(157-219)

SLBB domain (SLBB)

(75-128)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae R6

54.26

100

0.548
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

54.26

100

0.548
  comEA/celA/cilE Streptococcus pneumoniae Rx1

54.26

100

0.548
  comEA/celA/cilE Streptococcus pneumoniae D39

54.26

100

0.548
  comEA/celA/cilE Streptococcus mitis NCTC 12261

53.812

100

0.543
  comEA/celA/cilE Streptococcus mitis SK321

51.327

100

0.525
  comEA Streptococcus thermophilus LMD-9

43.534

100

0.457
  comEA Lactococcus lactis subsp. cremoris KW2

43.694

100

0.439
  comEA Latilactobacillus sakei subsp. sakei 23K

35.833

100

0.389

Multiple sequence alignment