Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   BFM96_RS06450 Genome accession   NZ_CP016953
Coordinates   1389222..1391462 (+) Length   746 a.a.
NCBI ID   WP_068991864.1    Uniprot ID   -
Organism   Streptococcus himalayensis strain HTS2     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1384222..1396462
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BFM96_RS06430 smpB 1386422..1386889 (+) 468 WP_068991851.1 SsrA-binding protein SmpB -
  BFM96_RS06435 - 1386899..1387492 (+) 594 WP_068991856.1 DUF4230 domain-containing protein -
  BFM96_RS06440 - 1387715..1388446 (+) 732 WP_145939718.1 hypothetical protein -
  BFM96_RS06445 comEA/celA/cilE 1388573..1389238 (+) 666 WP_068991861.1 helix-hairpin-helix domain-containing protein Machinery gene
  BFM96_RS06450 comEC/celB 1389222..1391462 (+) 2241 WP_068991864.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  BFM96_RS06455 - 1392305..1392889 (+) 585 WP_068991866.1 GDSL-type esterase/lipase family protein -
  BFM96_RS06460 - 1392929..1393582 (+) 654 WP_068991869.1 uracil-DNA glycosylase -
  BFM96_RS06465 - 1393591..1394055 (+) 465 WP_068991872.1 8-oxo-dGTP diphosphatase -
  BFM96_RS06470 - 1394065..1394607 (+) 543 WP_068991874.1 2'-5' RNA ligase family protein -
  BFM96_RS06475 - 1394620..1395891 (+) 1272 WP_068991877.1 dihydroorotase -

Sequence

Protein


Download         Length: 746 a.a.        Molecular weight: 84436.00 Da        Isoelectric Point: 8.3245

>NTDB_id=194047 BFM96_RS06450 WP_068991864.1 1389222..1391462(+) (comEC/celB) [Streptococcus himalayensis strain HTS2]
MLQWIKKCPIPLIYLTVLLVWLYYAIYQGSVLAWGGFGFSMLLLWVRYAGKQAVYVCMILVFFACLFSYRSRTMERGMEL
NPPSPREILLLPDTIKVNGDSLSFRGKSQGQLFQAFYKLQTEQEKQRFQAQSDLLRLEIEGELSQAEGRRNFAGFDYREY
LKTQGIYRTLTIEHITSVQPVKTWNVLDKLSSWRRAAVVFIKQTFPQPMSNYMTGLLFGHLDTDFEEMNDLYSSLGIIHL
FALSGMQVGFFMDGFRKLLLRLGLKMETVTVIQYPFSLLYAGLTGFSVSVVRSLLQKLWGQAGVKGLDNFALTMMTLSLL
MPNFLLTAGGILSCAYSFLLSMIDTDGLSSFKKICYESAMISIGMLPILLFFFGEFQPWSIPLTFFFSFIFDVLLLPGLS
LIFLLAPLVAIAQVNPLFQLLEQIIRWVGSLTSHPLVLGQPSPILLLALLLFLAIFADKRQEKAWKMGLLGMITLLFFIC
KHPLENEVTIVDIGQGDSIFLRDMTGRNILIDVGGRVEVGKKENWQQRVSVPNAERTLIPYLKSRGVGCVDKLVLTHTDT
DHMGDMLVVAKALSIREVYVSKGSLTKQDFVEKLDQLGVRIHVVEIGDRLPIMGGYLEVLYPSGVGDGGNNDSIVLYGEL
LKTRFLFTGDLETEGEEEMMARFPNLRVDVLKAGHHGSKGSSSPAFLDQIKPQLALISAGKKNRYKHPHQETLDRFDERQ
IKVLRTDEQGAIRFTGWSEWKIETVR

Nucleotide


Download         Length: 2241 bp        

>NTDB_id=194047 BFM96_RS06450 WP_068991864.1 1389222..1391462(+) (comEC/celB) [Streptococcus himalayensis strain HTS2]
ATGTTACAGTGGATTAAGAAATGCCCGATTCCCCTGATTTATCTGACGGTTCTCTTGGTTTGGCTCTACTATGCGATTTA
CCAAGGCTCAGTGCTTGCTTGGGGCGGCTTTGGTTTTTCAATGTTGCTTCTTTGGGTTCGTTATGCTGGCAAACAGGCTG
TTTATGTTTGCATGATATTAGTGTTCTTTGCTTGTCTGTTTAGCTACCGAAGCCGAACCATGGAGCGGGGGATGGAGCTT
AATCCGCCGAGCCCAAGGGAAATTCTACTCTTGCCAGATACTATCAAGGTGAATGGGGATTCTCTATCCTTTCGAGGAAA
AAGTCAGGGACAACTATTTCAAGCCTTTTATAAACTACAAACTGAGCAAGAAAAGCAGCGTTTTCAAGCCCAGTCTGATC
TTCTACGCTTGGAGATAGAAGGAGAACTAAGTCAGGCAGAAGGACGGCGTAATTTTGCTGGATTTGATTACCGAGAATAC
TTGAAAACACAAGGAATTTACCGTACCTTGACCATTGAGCACATCACGTCTGTTCAGCCTGTGAAAACTTGGAATGTTTT
GGATAAGCTCTCTAGTTGGCGGAGAGCTGCAGTCGTCTTTATCAAACAGACCTTTCCTCAGCCCATGTCAAACTATATGA
CGGGTCTCTTATTTGGTCATTTGGATACGGATTTTGAGGAGATGAATGATCTCTACTCAAGTTTAGGGATTATTCATTTA
TTTGCCTTATCTGGCATGCAGGTTGGATTTTTCATGGATGGTTTTCGAAAACTTTTGCTCCGACTGGGCTTGAAAATGGA
AACCGTCACGGTCATCCAGTATCCATTTTCCTTGCTTTATGCGGGACTGACAGGTTTTTCTGTGTCTGTGGTTCGCAGTT
TACTCCAAAAATTATGGGGGCAGGCTGGGGTGAAGGGCTTGGATAATTTTGCCCTGACCATGATGACTTTGAGTCTTCTC
ATGCCCAATTTCTTGCTGACGGCTGGAGGAATTTTATCCTGCGCCTATTCTTTCTTGCTCAGTATGATAGATACGGATGG
TTTATCTTCTTTTAAGAAAATTTGCTATGAAAGTGCGATGATTTCCATCGGAATGTTACCTATTTTGCTCTTTTTCTTTG
GGGAATTTCAACCCTGGTCCATCCCTTTGACCTTTTTCTTTTCCTTTATTTTTGACGTTTTGCTCTTGCCAGGGCTTAGT
TTGATTTTTCTTCTTGCCCCTTTGGTCGCGATTGCGCAGGTCAATCCGCTCTTTCAGCTCTTGGAGCAGATCATTCGTTG
GGTAGGAAGTCTGACTTCTCATCCCCTGGTTTTGGGGCAGCCGAGTCCTATCTTGCTCCTTGCTCTACTGCTTTTCCTTG
CGATTTTTGCTGATAAACGGCAAGAAAAAGCTTGGAAGATGGGGTTACTTGGGATGATTACTCTTTTGTTTTTTATCTGT
AAACATCCTCTAGAAAATGAAGTGACCATTGTGGATATCGGGCAGGGGGATAGTATCTTTTTGCGTGATATGACAGGAAG
AAATATATTGATTGATGTTGGTGGGCGAGTTGAAGTTGGTAAGAAAGAGAATTGGCAACAGCGGGTGAGTGTGCCTAATG
CGGAGAGGACCTTGATTCCCTATCTAAAAAGCCGCGGAGTTGGGTGTGTGGATAAGTTGGTGCTCACCCATACCGATACA
GACCACATGGGAGATATGCTAGTGGTGGCAAAAGCTCTATCTATCCGAGAGGTTTATGTGTCAAAAGGAAGTTTAACCAA
GCAAGACTTTGTTGAAAAACTAGACCAGTTGGGTGTACGAATTCATGTCGTAGAAATTGGAGACCGTTTACCGATTATGG
GCGGATATCTAGAGGTGCTATACCCAAGTGGTGTGGGTGACGGTGGCAATAATGACTCCATCGTCTTATATGGGGAGTTG
CTCAAGACTAGATTTCTATTTACAGGAGATTTGGAGACAGAAGGAGAAGAGGAGATGATGGCTAGATTTCCAAATCTTCG
GGTCGACGTCTTAAAGGCAGGACACCATGGCTCTAAAGGCAGCTCAAGTCCGGCATTTCTAGACCAGATAAAGCCTCAGT
TGGCCTTGATTTCCGCGGGAAAGAAAAATCGCTACAAACATCCGCACCAAGAAACCCTAGATCGATTTGATGAACGTCAG
ATAAAGGTTTTGAGAACAGATGAACAAGGAGCCATTCGCTTTACAGGCTGGTCAGAATGGAAAATCGAAACCGTTCGCTA
A

Domains

Predicted by InterproScan.

Competence protein (Competence)

(216-458)

Metallo-beta-lactamase superfamily (Lactamase_B)

(494-700)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis SK321

57.831

100

0.579
  comEC/celB Streptococcus mitis NCTC 12261

57.239

100

0.572
  comEC/celB Streptococcus pneumoniae TIGR4

56.493

100

0.566
  comEC/celB Streptococcus pneumoniae Rx1

56.091

100

0.562
  comEC/celB Streptococcus pneumoniae D39

56.091

100

0.562
  comEC/celB Streptococcus pneumoniae R6

56.091

100

0.562
  comEC Lactococcus lactis subsp. cremoris KW2

47.703

99.196

0.473

Multiple sequence alignment