Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   BFM96_RS03495 Genome accession   NZ_CP016953
Coordinates   715944..717197 (+) Length   417 a.a.
NCBI ID   WP_068990369.1    Uniprot ID   -
Organism   Streptococcus himalayensis strain HTS2     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 710944..722197
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BFM96_RS03470 mutL 710986..712932 (+) 1947 WP_068990358.1 DNA mismatch repair endonuclease MutL -
  BFM96_RS03475 - 712950..714170 (+) 1221 WP_068994141.1 MFS transporter -
  BFM96_RS03480 ruvA 714176..714766 (+) 591 WP_068990361.1 Holliday junction branch migration protein RuvA -
  BFM96_RS03485 - 714778..715344 (+) 567 WP_068990364.1 DNA-3-methyladenine glycosylase I -
  BFM96_RS03490 - 715337..715891 (+) 555 WP_068990366.1 GNAT family N-acetyltransferase -
  BFM96_RS03495 cinA 715944..717197 (+) 1254 WP_068990369.1 competence/damage-inducible protein A Machinery gene
  BFM96_RS03500 recA 717230..718429 (+) 1200 WP_068990372.1 recombinase RecA Machinery gene
  BFM96_RS03505 spx 718791..719189 (+) 399 WP_068990375.1 transcriptional regulator Spx -
  BFM96_RS03510 - 719327..719899 (+) 573 WP_068990378.1 SP0191 family lipoprotein -
  BFM96_RS03515 - 720098..720364 (+) 267 WP_068994144.1 IreB family regulatory phosphoprotein -
  BFM96_RS03520 ruvX 720364..720783 (+) 420 WP_068990381.1 Holliday junction resolvase RuvX -
  BFM96_RS03525 - 720802..721113 (+) 312 WP_068990383.1 DUF1292 domain-containing protein -

Sequence

Protein


Download         Length: 417 a.a.        Molecular weight: 45011.62 Da        Isoelectric Point: 5.1992

>NTDB_id=194005 BFM96_RS03495 WP_068990369.1 715944..717197(+) (cinA) [Streptococcus himalayensis strain HTS2]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLAGIGVDVYFQTAVGDNEQRLLSVLEIAQKRSDLVILTGGLGPTEDDLTKQT
LARFLGRDLVFEASAVEKLDAFFAERPPSARTPNNERQAQIIAGSTPLQNHTGLAVGGLIQVEGVTYVVLPGPPSELKPM
VVKELLPLLDQGEQLYSRVLRFFGIGESRLVTILADLIDQQTDPTLAPYAKVGEVTLRLSTKSKTHALAQEKLNQLEQKI
LANEEVAACLYGYGEENSLLQVTVELLKERKLTITAAESLTAGLFQANLADQAGISQIFKGGFVTYSLEEKSKMLGIPKE
DLEKHGVVSAFTAEKMAEQARKLTDSTLGVSLTGVAGPDSLEGHPPGTVFIGLSSSKARQAYLVSARGRSRQDIRQIAVL
HALNLVRKTLLNADDLV

Nucleotide


Download         Length: 1254 bp        

>NTDB_id=194005 BFM96_RS03495 WP_068990369.1 715944..717197(+) (cinA) [Streptococcus himalayensis strain HTS2]
ATGAAGGCAGAAATTATTGCGGTTGGAACTGAGATCCTGACCGGACAAATCGTCAATACCAATGCTCAATTTTTGTCGGA
AAAGCTCGCAGGAATTGGGGTAGATGTGTATTTCCAAACGGCAGTGGGAGATAATGAACAACGGCTCTTGTCCGTCTTAG
AAATTGCCCAAAAGCGAAGTGATTTGGTGATTTTAACAGGTGGTTTGGGGCCGACGGAGGATGATTTGACCAAGCAAACC
TTGGCACGTTTTCTAGGTCGAGATTTGGTCTTTGAAGCATCAGCTGTTGAGAAATTGGATGCCTTCTTTGCCGAACGGCC
GCCTAGTGCTCGCACGCCTAACAATGAGCGTCAGGCTCAAATTATCGCTGGGAGTACCCCGCTACAAAATCACACGGGTC
TTGCTGTTGGAGGATTGATCCAAGTAGAGGGTGTGACCTATGTCGTCCTACCGGGTCCTCCGAGCGAACTAAAACCAATG
GTGGTCAAGGAACTCTTGCCACTTCTCGACCAAGGCGAGCAATTGTATTCACGGGTTCTTCGCTTTTTTGGGATTGGGGA
AAGTCGTTTGGTGACCATTTTAGCCGATTTGATTGACCAGCAGACGGATCCAACCTTGGCTCCTTATGCGAAAGTCGGAG
AAGTGACTCTTCGGTTGTCCACCAAATCTAAGACACATGCCCTTGCCCAAGAAAAACTCAATCAGCTTGAACAGAAGATT
CTTGCCAATGAAGAAGTCGCTGCCTGCCTTTACGGTTATGGCGAGGAGAATTCTCTCTTGCAGGTGACCGTAGAACTCCT
GAAAGAAAGAAAGTTAACCATCACAGCTGCTGAAAGCTTGACAGCTGGGCTTTTTCAGGCCAATCTCGCGGATCAAGCTG
GGATTTCCCAGATTTTCAAGGGTGGTTTTGTCACCTACAGTTTGGAAGAAAAGAGCAAGATGTTAGGTATTCCTAAAGAG
GACTTGGAAAAGCATGGGGTTGTATCTGCTTTTACGGCTGAGAAAATGGCAGAGCAGGCTAGAAAGCTGACCGATAGCAC
CCTTGGTGTGAGCTTGACAGGAGTTGCTGGGCCAGATAGCCTAGAAGGACATCCTCCAGGGACAGTCTTTATTGGCTTGT
CTTCGAGTAAGGCAAGGCAAGCTTATTTGGTCAGTGCCAGAGGGAGAAGTCGGCAAGATATTCGCCAAATCGCAGTCTTA
CACGCCTTAAACCTCGTACGGAAAACTTTATTAAATGCTGATGATTTGGTATAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(258-410)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-241)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

72.967

100

0.731
  cinA Streptococcus mitis SK321

72.422

100

0.724
  cinA Streptococcus mitis NCTC 12261

71.463

100

0.715
  cinA Streptococcus pneumoniae TIGR4

71.223

100

0.712
  cinA Streptococcus pneumoniae Rx1

70.983

100

0.71
  cinA Streptococcus pneumoniae R6

70.983

100

0.71
  cinA Streptococcus pneumoniae D39

70.743

100

0.707
  cinA Streptococcus suis isolate S10

55.474

98.561

0.547
  cinA Bacillus subtilis subsp. subtilis str. 168

48.184

99.041

0.477

Multiple sequence alignment