Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   FBA2_RS06620 Genome accession   NZ_CP016028
Coordinates   1311092..1311967 (-) Length   291 a.a.
NCBI ID   WP_039099523.1    Uniprot ID   -
Organism   Latilactobacillus curvatus strain FBA2     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1306092..1316967
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FBA2_RS06585 (FBA2_06585) - 1307193..1308203 (-) 1011 WP_064777314.1 class I SAM-dependent methyltransferase -
  FBA2_RS06590 (FBA2_06590) - 1308328..1308651 (-) 324 WP_039099486.1 hypothetical protein -
  FBA2_RS06595 (FBA2_06595) - 1308629..1309027 (-) 399 WP_235601662.1 ComGF family competence protein -
  FBA2_RS10165 - 1309052..1309105 (-) 54 Protein_1298 hypothetical protein -
  FBA2_RS09820 (FBA2_06600) - 1309080..1309307 (-) 228 WP_004270907.1 hypothetical protein -
  FBA2_RS06605 (FBA2_06605) - 1309372..1309731 (-) 360 WP_158022155.1 hypothetical protein -
  FBA2_RS06610 (FBA2_06610) comGC 1309796..1310104 (-) 309 WP_064777316.1 competence type IV pilus major pilin ComGC Machinery gene
  FBA2_RS06615 (FBA2_06615) comGB 1310101..1311102 (-) 1002 WP_064777317.1 type II secretion system F family protein Machinery gene
  FBA2_RS06620 (FBA2_06620) comGA 1311092..1311967 (-) 876 WP_039099523.1 competence type IV pilus ATPase ComGA Machinery gene
  FBA2_RS06625 (FBA2_06625) - 1312071..1312802 (-) 732 WP_004270897.1 YebC/PmpR family DNA-binding transcriptional regulator -
  FBA2_RS06630 (FBA2_06630) - 1312892..1313392 (-) 501 WP_039099520.1 VanZ family protein -
  FBA2_RS06635 (FBA2_06635) - 1313495..1313872 (+) 378 WP_039099519.1 hypothetical protein -
  FBA2_RS06645 (FBA2_06645) - 1314053..1314388 (-) 336 WP_052202779.1 hypothetical protein -
  FBA2_RS06650 (FBA2_06650) - 1314583..1314822 (+) 240 WP_004270892.1 cytochrome b5 domain-containing protein -
  FBA2_RS06655 (FBA2_06655) - 1314913..1315926 (-) 1014 WP_004265264.1 YeiH family protein -
  FBA2_RS06660 (FBA2_06660) - 1316035..1316862 (+) 828 WP_064777318.1 LysR family transcriptional regulator -

Sequence

Protein


Download         Length: 291 a.a.        Molecular weight: 32042.84 Da        Isoelectric Point: 5.5654

>NTDB_id=185463 FBA2_RS06620 WP_039099523.1 1311092..1311967(-) (comGA) [Latilactobacillus curvatus strain FBA2]
MTEVLTTLLQKCATEKAQDLYFRPLSTGWAIIERLATGLKPLQKVTLSEGNQWLNQMKYQAGMDISETRRPQTGRSAIEV
AGELIYLRLATVGDFLNRESLVVRFIYPIGQTYHCDDSQILSRLMQLIQQPGLLLFAGPTGSGKTTSLYYLAEQVMQDKM
VVAIEDPIEIQQPAFLQLQVNEAAGLTYAALLKISLRLRPDTLIIGEIRDLQTAQHAVSAALSGHLVLSTIHARSTTGVM
DRLLDLGISHSQLTACLAGVAYQSLVVDGHNVAAHYELATAQQLEEAVHED

Nucleotide


Download         Length: 876 bp        

>NTDB_id=185463 FBA2_RS06620 WP_039099523.1 1311092..1311967(-) (comGA) [Latilactobacillus curvatus strain FBA2]
ATGACCGAAGTATTAACAACCCTTTTGCAAAAGTGCGCAACGGAAAAAGCGCAGGATCTTTATTTTCGACCACTATCGAC
GGGTTGGGCAATTATTGAACGCTTAGCGACAGGACTAAAGCCGTTACAAAAAGTTACTCTGTCAGAAGGCAATCAATGGC
TCAATCAAATGAAGTATCAAGCGGGAATGGATATCAGTGAAACTCGGCGTCCACAGACCGGCCGTTCAGCGATCGAGGTG
GCAGGTGAATTGATTTATTTACGGTTGGCAACCGTGGGGGATTTTTTGAATCGGGAAAGTTTAGTTGTTCGTTTCATTTA
TCCCATTGGGCAGACTTATCATTGCGACGACTCGCAGATTTTAAGTCGTTTAATGCAGTTAATTCAGCAACCAGGATTAT
TGCTATTTGCCGGTCCAACTGGTTCAGGGAAGACAACAAGTTTGTACTATCTTGCGGAACAAGTCATGCAAGATAAGATG
GTGGTTGCGATTGAAGATCCGATAGAGATTCAACAGCCAGCGTTCTTACAGTTACAAGTGAATGAAGCCGCAGGGTTAAC
CTATGCAGCATTGTTGAAAATCAGTTTGCGATTACGGCCTGATACCTTAATTATTGGTGAGATTCGCGACTTACAGACGG
CCCAACACGCGGTTTCTGCGGCGTTGAGCGGTCACTTGGTACTAAGTACGATTCACGCGCGAAGTACAACGGGGGTGATG
GACCGTCTATTAGATCTTGGAATTAGCCACTCACAATTAACCGCTTGTTTAGCGGGTGTTGCCTATCAATCACTAGTGGT
CGACGGCCACAATGTAGCGGCCCACTATGAGTTAGCAACTGCACAACAATTGGAGGAGGCTGTTCATGAAGACTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-265)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Latilactobacillus sakei subsp. sakei 23K

69.892

95.876

0.67
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

43.015

93.471

0.402
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

42.593

92.784

0.395
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

41.573

91.753

0.381
  comGA/cglA/cilD Streptococcus pneumoniae R6

41.573

91.753

0.381
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

41.573

91.753

0.381
  comGA/cglA/cilD Streptococcus pneumoniae D39

41.573

91.753

0.381
  comGA Lactococcus lactis subsp. cremoris KW2

41.603

90.034

0.375
  comYA Streptococcus mutans UA140

37.113

100

0.371
  comYA Streptococcus mutans UA159

37.113

100

0.371
  comYA Streptococcus gordonii str. Challis substr. CH1

39.194

93.814

0.368

Multiple sequence alignment