Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB   Type   Machinery gene
Locus tag   LLUC06_RS12075 Genome accession   NZ_CP015902
Coordinates   2402778..2403851 (-) Length   357 a.a.
NCBI ID   WP_081213814.1    Uniprot ID   A0A1V0P560
Organism   Lactococcus lactis subsp. lactis strain UC06     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2397778..2408851
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLUC06_RS12030 (LLUC06_2339) - 2397917..2398726 (-) 810 WP_014570791.1 metal ABC transporter permease -
  LLUC06_RS12035 (LLUC06_2340) - 2398719..2399456 (-) 738 WP_012898617.1 metal ABC transporter ATP-binding protein -
  LLUC06_RS12040 (LLUC06_2341) - 2399633..2400475 (-) 843 WP_081213761.1 metal ABC transporter substrate-binding protein -
  LLUC06_RS12045 (LLUC06_2342) - 2400472..2400909 (-) 438 WP_010906313.1 zinc-dependent MarR family transcriptional regulator -
  LLUC06_RS12050 (LLUC06_2343) comGG 2400990..2401274 (-) 285 WP_017865155.1 competence type IV pilus minor pilin ComGG Machinery gene
  LLUC06_RS12055 (LLUC06_2344) comGF 2401313..2401759 (-) 447 WP_058203710.1 competence type IV pilus minor pilin ComGF Machinery gene
  LLUC06_RS12060 (LLUC06_2345) comGE 2401722..2402018 (-) 297 WP_033900709.1 competence type IV pilus minor pilin ComGE Machinery gene
  LLUC06_RS12065 (LLUC06_2346) comGD 2401990..2402421 (-) 432 WP_012898621.1 competence type IV pilus minor pilin ComGD Machinery gene
  LLUC06_RS12070 (LLUC06_2347) comGC 2402381..2402764 (-) 384 WP_012898622.1 competence type IV pilus major pilin ComGC Machinery gene
  LLUC06_RS12075 (LLUC06_2348) comGB 2402778..2403851 (-) 1074 WP_081213814.1 competence type IV pilus assembly protein ComGB Machinery gene
  LLUC06_RS12080 (LLUC06_2349) comGA 2403745..2404682 (-) 938 Protein_2349 competence type IV pilus ATPase ComGA -

Sequence

Protein


Download         Length: 357 a.a.        Molecular weight: 40314.60 Da        Isoelectric Point: 10.3921

>NTDB_id=183098 LLUC06_RS12075 WP_081213814.1 2402778..2403851(-) (comGB) [Lactococcus lactis subsp. lactis strain UC06]
MSLGHQKIGIKKLISYLQMDISHLLKPKGKKLRLIKQAKLIQLMGNLLNSGFNLGEVINFLSLSKLVEKEFTLKMKEGLA
SGQVLSEILESLSFSKNVVTQLALVEVHGNLSGTMQLVELHLKKQLKVKNKLVEVATYPILLLIFLIGIMWGLKNYLLPQ
LNSGSNFATLLINHLPLVFFSFGAFIFLLTALSVTLFKRKSAIMNFTFLVKLPLVHSFIRLYLTAYFAREWGNLIAQGVE
LRQIINLMKKKKSRIFSEVGKNLDLELNAGRSFEQAVSKLALFLPELSLMIEYGAIKDKLGLELSLYADECWEQFFTKIG
RLMQLIQPLVFIFVALMIILLYAAMLLPIYSNMGSGI

Nucleotide


Download         Length: 1074 bp        

>NTDB_id=183098 LLUC06_RS12075 WP_081213814.1 2402778..2403851(-) (comGB) [Lactococcus lactis subsp. lactis strain UC06]
TTGAGTCTTGGTCATCAGAAAATTGGAATAAAAAAATTGATCAGCTACTTACAAATGGATATCTCACACCTACTGAAGCC
AAAAGGGAAAAAATTAAGACTGATTAAACAAGCCAAACTTATCCAACTGATGGGAAATCTTTTGAATAGTGGATTTAATT
TAGGAGAAGTGATAAATTTCTTATCTTTATCAAAACTTGTGGAAAAAGAATTTACATTAAAAATGAAAGAAGGTCTCGCT
TCTGGTCAAGTTTTATCAGAGATTTTAGAAAGTCTTTCATTTTCTAAAAATGTGGTGACACAACTTGCTTTGGTAGAAGT
GCATGGTAACTTGTCAGGGACGATGCAATTGGTTGAACTTCATCTAAAAAAACAGCTTAAAGTTAAAAATAAATTAGTGG
AAGTTGCTACTTATCCAATATTGTTATTAATTTTTCTGATTGGAATTATGTGGGGCTTAAAAAATTATTTACTACCACAA
CTCAATAGTGGCAGTAACTTTGCTACTCTATTGATTAATCATTTACCCTTAGTATTTTTTTCGTTTGGAGCTTTTATATT
TTTACTGACAGCTTTGTCAGTAACTCTTTTTAAACGAAAATCAGCAATAATGAATTTTACATTTCTTGTTAAATTACCTC
TGGTTCATTCTTTTATCCGTTTATATTTAACAGCTTACTTTGCAAGAGAATGGGGAAATCTAATTGCTCAAGGTGTTGAA
TTACGTCAAATTATTAACTTGATGAAAAAAAAAAAAAGTCGAATTTTTTCAGAAGTTGGCAAGAATCTTGATTTAGAATT
GAATGCTGGTCGGTCTTTTGAACAAGCTGTCAGTAAACTTGCGCTTTTTTTACCCGAGCTCTCGTTAATGATTGAATATG
GAGCTATTAAAGATAAATTAGGCTTAGAGCTTTCGCTTTATGCGGATGAATGTTGGGAACAATTTTTTACAAAGATAGGT
CGTTTAATGCAATTAATCCAACCTCTTGTTTTTATTTTCGTAGCATTGATGATTATTTTGCTATATGCAGCCATGTTACT
CCCCATCTATTCAAATATGGGTTCGGGAATATAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(41-159)

Type II secretion system (T2SS), protein F (T2SSF)

(227-348)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1V0P560

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB Lactococcus lactis subsp. cremoris KW2

83.578

95.518

0.798
  comYB Streptococcus gordonii str. Challis substr. CH1

53.372

95.518

0.51
  comYB Streptococcus mutans UA140

53.079

95.518

0.507
  comYB Streptococcus mutans UA159

52.786

95.518

0.504
  comGB/cglB Streptococcus mitis SK321

51.045

93.838

0.479
  comGB/cglB Streptococcus pneumoniae TIGR4

50.746

93.838

0.476
  comGB/cglB Streptococcus pneumoniae Rx1

50.746

93.838

0.476
  comGB/cglB Streptococcus pneumoniae D39

50.746

93.838

0.476
  comGB/cglB Streptococcus pneumoniae R6

50.746

93.838

0.476
  comGB/cglB Streptococcus mitis NCTC 12261

50.149

93.838

0.471

Multiple sequence alignment