Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   A6M16_RS06120 Genome accession   NZ_CP015557
Coordinates   1236424..1237086 (-) Length   220 a.a.
NCBI ID   WP_079769281.1    Uniprot ID   -
Organism   Streptococcus suis strain DN13     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1231424..1242086
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6M16_RS06105 (A6M16_06110) - 1232312..1233139 (-) 828 WP_024416480.1 hypothetical protein -
  A6M16_RS06110 (A6M16_06115) - 1233233..1233889 (-) 657 WP_002935353.1 CBS domain-containing protein -
  A6M16_RS11225 - 1234072..1234194 (-) 123 Protein_1154 IS982 family transposase -
  A6M16_RS06115 (A6M16_06120) comEC/celB 1234203..1236440 (-) 2238 WP_044756286.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  A6M16_RS06120 (A6M16_06125) comEA/celA/cilE 1236424..1237086 (-) 663 WP_079769281.1 helix-hairpin-helix domain-containing protein Machinery gene
  A6M16_RS06125 (A6M16_06130) - 1237153..1237899 (-) 747 WP_014638160.1 lysophospholipid acyltransferase family protein -
  A6M16_RS06130 (A6M16_06135) - 1238046..1239491 (+) 1446 WP_044756288.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  A6M16_RS06135 (A6M16_06140) - 1239643..1240428 (+) 786 WP_014636900.1 ABC transporter ATP-binding protein -
  A6M16_RS06140 (A6M16_06145) - 1240441..1241370 (+) 930 WP_015646964.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23451.24 Da        Isoelectric Point: 4.1234

>NTDB_id=180690 A6M16_RS06120 WP_079769281.1 1236424..1237086(-) (comEA/celA/cilE) [Streptococcus suis strain DN13]
MDTIKTYIEMLKEYKWQIALPAVAGLLMATFLIFSQPAKSDQTGLTDFPQTEQTSSTSDLVEETSTEVSKEPSLLVVDVK
GAVVKPGLYTLEADARVNDAVEAAGGLTSQADPKSINLAQKLSDEAVVYVASKDENISVVASTTTSSAMSQEEKNTSLVN
LNTATEADLQTISGIGAKRATDIIAYREANGGFKSVDDLNNVSGIGDKTMESIRPYVTVD

Nucleotide


Download         Length: 663 bp        

>NTDB_id=180690 A6M16_RS06120 WP_079769281.1 1236424..1237086(-) (comEA/celA/cilE) [Streptococcus suis strain DN13]
ATGGATACGATTAAAACTTATATAGAAATGCTTAAAGAATACAAGTGGCAAATTGCTCTGCCCGCAGTGGCTGGCTTGCT
AATGGCGACGTTTTTAATCTTCAGTCAACCAGCCAAGTCTGACCAGACAGGACTGACAGACTTTCCACAGACCGAACAAA
CTTCTAGCACCTCTGACTTGGTCGAGGAAACCAGTACAGAAGTAAGTAAGGAGCCCAGCCTGCTGGTCGTTGATGTCAAA
GGAGCGGTAGTAAAACCAGGACTCTACACTTTAGAAGCTGATGCGCGTGTTAATGATGCAGTTGAAGCAGCTGGTGGCTT
GACCAGTCAGGCAGATCCCAAATCTATCAATCTGGCTCAGAAGCTCAGCGACGAGGCGGTGGTCTATGTGGCCAGCAAGG
ATGAAAATATCTCGGTGGTGGCCAGCACGACTACCAGCTCTGCTATGTCCCAAGAAGAAAAAAACACCAGTCTAGTCAAT
CTGAATACGGCGACTGAGGCGGACTTGCAGACCATTTCTGGTATTGGTGCCAAGCGAGCGACGGACATTATCGCCTATCG
TGAGGCCAACGGCGGCTTCAAGTCAGTGGACGACCTCAACAATGTTTCGGGCATTGGCGACAAGACCATGGAAAGCATTC
GACCTTATGTCACGGTCGATTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(76-130)

Helix-hairpin-helix motif (HHH_3)

(155-218)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

49.315

99.545

0.491
  comEA/celA/cilE Streptococcus pneumoniae Rx1

48.858

99.545

0.486
  comEA/celA/cilE Streptococcus pneumoniae D39

48.858

99.545

0.486
  comEA/celA/cilE Streptococcus pneumoniae R6

48.858

99.545

0.486
  comEA/celA/cilE Streptococcus mitis NCTC 12261

48.858

99.545

0.486
  comEA/celA/cilE Streptococcus mitis SK321

47.297

100

0.477
  comEA Streptococcus thermophilus LMD-9

60.784

69.545

0.423
  comEA Lactococcus lactis subsp. cremoris KW2

38.496

100

0.395
  comEA Bacillus subtilis subsp. subtilis str. 168

38.095

95.455

0.364

Multiple sequence alignment