Detailed information NTG0180689

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: A6M16_RS06115
• Genome accession: NZ_CP015557
• Coordinates: 1234203..1236440 (-)
• Length: 745 a.a.
• NCBI ID: WP_044756286.1
• Uniprot ID: -
• Organism: Streptococcus suis strain DN13
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1229203..1241440

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6M16_RS06090 (A6M16_06095)	tmk	1229319..1229957 (-)	639	WP_014735979.1	dTMP kinase	-
A6M16_RS06095 (A6M16_06100)	-	1230132..1230998 (+)	867	WP_002935357.1	YitT family protein	-
A6M16_RS06100 (A6M16_06105)	-	1231035..1232306 (-)	1272	WP_044671016.1	toxic anion resistance protein	-
A6M16_RS06105 (A6M16_06110)	-	1232312..1233139 (-)	828	WP_024416480.1	hypothetical protein	-
A6M16_RS06110 (A6M16_06115)	-	1233233..1233889 (-)	657	WP_002935353.1	CBS domain-containing protein	-
A6M16_RS11225	-	1234072..1234194 (-)	123	Protein_1154	IS982 family transposase	-
A6M16_RS06115 (A6M16_06120)	comEC/celB	1234203..1236440 (-)	2238	WP_044756286.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
A6M16_RS06120 (A6M16_06125)	comEA/celA/cilE	1236424..1237086 (-)	663	WP_079769281.1	helix-hairpin-helix domain-containing protein	Machinery gene
A6M16_RS06125 (A6M16_06130)	-	1237153..1237899 (-)	747	WP_014638160.1	lysophospholipid acyltransferase family protein	-
A6M16_RS06130 (A6M16_06135)	-	1238046..1239491 (+)	1446	WP_044756288.1	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	-
A6M16_RS06135 (A6M16_06140)	-	1239643..1240428 (+)	786	WP_014636900.1	ABC transporter ATP-binding protein	-
A6M16_RS06140 (A6M16_06145)	-	1240441..1241370 (+)	930	WP_015646964.1	ABC transporter substrate-binding protein	-

Sequence

Protein

• Length: 745 a.a.
• Molecular weight: 83981.80 Da
• Isoelectric Point: 7.0407

>NTDB_id=180689 A6M16_RS06115 WP_044756286.1 1234203..1236440(-) (comEC/celB) [Streptococcus suis strain DN13]
MSRSIKLPCQPIHLAVLAVAVYFAVHSFSLLTMGLLSLILAVFGVRQGKTVFLKTLPLLALCGLFFGCQKVQWERADQSA
PEQVTTVQVIPDTIDINGDSLSFRGWADGQTYQVFYKLASQEEQTYFQELTDLVQLDVEAEVSLPAGQRNFKGFDYQAYL
KTQGIYRTVKLTAIKKIVPVQSWNVFDWLSSWRRQALVYVKTNFPAPMSHYMTGLLFGDLDSDFDQMSDLYSSLGIIHLF
ALSGMQVGFFIDKFRWILLRLGLTKEAVDKLQIPFSIVYAGLTGFSVSVVRSLVQKILGNLGLRKLDNFAVTVFVCLLIL
PRFLLTAGGVLTFTYAFLLTVFDFEDLGQVKKAAVESLSISLGILPILMTYFYAFQPLSILLTFVFSFIFDVLLLPGLSV
IFLLSPIIKITWVNGFFVFMEKIIVWVADLGFRPWILGKPSELVLLLLLVSLFLLYDFHRRKKWLLGLSLVLALLFFITK
HPLENEVTVVDIGQGDSIFLRDMRGRTVLIDVGGRVDFAAKEAWQERSRQANAERTLIPYLHSRGVDRIDSLVLTHTDTD
HVGDVLEVAKQVQIGRIVVSQGSLTVPDFVATLKEINVPVHVVKVGDRLPIFDSYLEVLYPDGTGDGGNNDSIVLYGRLL
ETNFLFTGDLEQGELDLIATYPNLPVDVLKAGHHGSKGSSYPEFLDHIGAKIALVSAGENNRYKHPHQETLDRFDSRNIQ
VYRTDQQGAIRFRGWKEWRIETVRR

Nucleotide

• Length: 2238 bp

>NTDB_id=180689 A6M16_RS06115 WP_044756286.1 1234203..1236440(-) (comEC/celB) [Streptococcus suis strain DN13]
ATGTCACGGTCGATTAAGCTCCCCTGCCAGCCCATTCACCTGGCAGTCTTGGCGGTGGCAGTTTACTTTGCAGTCCATTC
TTTTTCCCTCTTGACAATGGGCCTGCTGAGTTTGATATTAGCTGTCTTTGGTGTTCGGCAAGGTAAGACAGTTTTTCTCA
AAACGCTGCCGCTTCTAGCCTTATGTGGTCTGTTTTTCGGATGCCAGAAGGTCCAATGGGAGCGGGCAGACCAGTCAGCC
CCAGAACAAGTCACAACTGTGCAGGTCATTCCAGATACCATTGACATTAACGGGGACAGCCTGTCCTTTCGTGGTTGGGC
TGACGGACAAACCTATCAGGTGTTTTACAAATTAGCCAGTCAGGAGGAGCAGACTTATTTTCAAGAGCTGACTGATCTGG
TCCAGCTAGATGTGGAAGCAGAGGTCAGCCTGCCAGCTGGTCAGCGGAATTTCAAGGGTTTTGACTATCAGGCCTATCTG
AAAACACAGGGTATCTATCGGACTGTCAAGCTAACGGCGATTAAGAAGATTGTCCCTGTCCAGTCTTGGAATGTTTTTGA
CTGGTTGTCAAGCTGGCGGAGGCAGGCCTTGGTCTATGTCAAAACCAATTTTCCGGCTCCCATGAGTCACTACATGACAG
GGCTCTTGTTTGGGGACTTGGATAGTGATTTCGACCAGATGAGTGACCTCTATTCTAGTCTCGGAATCATTCATCTCTTT
GCCCTGTCTGGTATGCAGGTTGGATTTTTCATCGATAAGTTTCGCTGGATTTTACTGCGTTTGGGCTTGACCAAGGAAGC
CGTAGATAAGTTGCAGATTCCCTTTTCAATTGTTTATGCTGGTTTGACAGGCTTTTCTGTGTCGGTGGTGCGGTCCTTGG
TCCAAAAAATTCTGGGTAATCTAGGCTTGCGGAAGTTGGATAACTTTGCGGTGACAGTTTTTGTCTGTCTGTTGATACTG
CCCCGATTTTTACTGACAGCAGGAGGAGTGCTGACTTTTACCTATGCTTTCTTGCTGACGGTTTTTGATTTTGAGGACTT
GGGGCAGGTCAAAAAGGCTGCGGTGGAGAGCCTCAGTATTTCGCTGGGAATTTTGCCGATTCTCATGACCTATTTCTATG
CCTTCCAGCCCTTGTCTATTCTCTTGACTTTTGTCTTTTCCTTTATCTTTGATGTCCTGCTCTTGCCAGGCTTGTCGGTC
ATTTTTCTCTTATCACCAATTATCAAGATTACCTGGGTCAACGGATTTTTCGTTTTTATGGAGAAAATCATTGTCTGGGT
GGCGGATTTGGGCTTTCGGCCTTGGATACTGGGCAAGCCGTCTGAGCTGGTCCTCTTGCTTTTGCTGGTCAGCCTCTTCT
TGCTCTACGATTTCCACAGGAGAAAGAAATGGCTTCTAGGACTGAGCTTGGTCCTCGCTCTGCTATTTTTCATCACCAAA
CACCCGCTGGAAAACGAGGTGACGGTGGTGGACATCGGGCAGGGGGACAGCATCTTTTTGCGGGATATGCGGGGGCGGAC
GGTTCTGATTGATGTGGGCGGTCGGGTCGATTTTGCGGCCAAGGAAGCGTGGCAGGAGCGGTCTCGGCAGGCAAATGCAG
AGCGGACTTTGATTCCCTATCTGCATAGTCGGGGCGTGGACAGGATTGATAGTTTGGTCCTGACGCACACCGATACAGAC
CATGTGGGCGATGTGCTGGAAGTGGCTAAGCAGGTGCAAATTGGTCGGATTGTCGTGTCGCAGGGAAGTCTGACGGTGCC
TGACTTTGTAGCAACCTTGAAAGAAATCAATGTGCCTGTCCATGTGGTAAAAGTGGGCGATCGCTTGCCGATTTTTGACT
CCTATCTGGAGGTCCTCTATCCAGACGGGACAGGCGACGGCGGCAATAATGACTCCATTGTCCTTTACGGTCGCTTGTTG
GAAACTAACTTTCTCTTTACAGGAGACCTGGAGCAAGGGGAGTTGGACTTGATAGCAACCTATCCTAATCTGCCTGTCGA
TGTCCTCAAAGCCGGTCACCATGGTTCAAAAGGCTCTTCCTATCCAGAATTTTTAGACCATATCGGTGCCAAGATTGCTC
TGGTATCTGCTGGAGAAAATAACCGCTACAAGCATCCTCATCAAGAAACCTTGGACCGCTTTGACAGTCGGAATATCCAA
GTCTATCGTACCGACCAGCAAGGAGCCATCCGCTTCCGAGGTTGGAAGGAGTGGAGGATTGAAACGGTGAGGAGGTAA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (30-175)

• Competence protein (Competence) (215-461)

• Metallo-beta-lactamase superfamily (Lactamase_B) (493-698)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	54.324	99.329	0.54
comEC/celB	Streptococcus mitis NCTC 12261	53.469	98.658	0.528
comEC/celB	Streptococcus pneumoniae TIGR4	52.582	98.792	0.519
comEC/celB	Streptococcus pneumoniae Rx1	52.31	98.792	0.517
comEC/celB	Streptococcus pneumoniae D39	52.31	98.792	0.517
comEC/celB	Streptococcus pneumoniae R6	52.31	98.792	0.517
comEC	Lactococcus lactis subsp. cremoris KW2	48.728	100	0.489