Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   A6M16_RS00380 Genome accession   NZ_CP015557
Coordinates   64492..65673 (+) Length   393 a.a.
NCBI ID   WP_044685818.1    Uniprot ID   -
Organism   Streptococcus suis strain DN13     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 59492..70673
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6M16_RS00360 (A6M16_00360) - 59520..61043 (+) 1524 WP_063725143.1 hypothetical protein -
  A6M16_RS00365 (A6M16_00365) mutL 61161..63098 (+) 1938 WP_063725144.1 DNA mismatch repair endonuclease MutL -
  A6M16_RS00370 (A6M16_00370) ruvA 63137..63727 (+) 591 WP_063725145.1 Holliday junction branch migration protein RuvA -
  A6M16_RS00375 (A6M16_00375) - 63886..64455 (+) 570 WP_014637285.1 DNA-3-methyladenine glycosylase I -
  A6M16_RS00380 (A6M16_00380) cinA 64492..65673 (+) 1182 WP_044685818.1 competence/damage-inducible protein A Machinery gene
  A6M16_RS00385 (A6M16_00385) recA 65725..66876 (+) 1152 WP_029172053.1 recombinase RecA Machinery gene
  A6M16_RS00390 (A6M16_00390) spx 67112..67510 (+) 399 WP_002939362.1 transcriptional regulator Spx -
  A6M16_RS00395 (A6M16_00395) - 67610..67876 (+) 267 WP_002939360.1 IreB family regulatory phosphoprotein -
  A6M16_RS00400 (A6M16_00400) ruvX 67876..68295 (+) 420 WP_002939356.1 Holliday junction resolvase RuvX -
  A6M16_RS00405 (A6M16_00405) - 68307..68627 (+) 321 WP_002939343.1 DUF1292 domain-containing protein -
  A6M16_RS11320 - 68786..68908 (+) 123 WP_257571720.1 hypothetical protein -
  A6M16_RS00410 (A6M16_00410) rpsJ 69117..69425 (+) 309 WP_014735259.1 30S ribosomal protein S10 -
  A6M16_RS00415 (A6M16_00415) rplC 69562..70188 (+) 627 WP_011921686.1 50S ribosomal protein L3 -

Sequence

Protein


Download         Length: 393 a.a.        Molecular weight: 42948.79 Da        Isoelectric Point: 4.3708

>NTDB_id=180656 A6M16_RS00380 WP_044685818.1 64492..65673(+) (cinA) [Streptococcus suis strain DN13]
MKAELIAVGTEILTGQIINTNAQFLSEKCAELGIDVYFHTAVGDNENRLLSVLEVASQRSDLVILCGGLGPTEDDLTKQT
LATFLGRNLVFDELAMAKLDRFFASRPGRVRTPNNERQAQIVEGSQALQNPAGLAVGGMIEQDGVTYIVLPGPPSELKAM
FSESLLPLLSQSQQQLYSRVLRFFSIGESQLVTVLADLIDKQTDPTLAPYAKVGEVTLRLSTKATSQEEANLRLNQLEEE
ILQHDKLADYFYAYGEDNSLVKTVATRLAEKRQTIAIVEQGTGGLLQAELSLALADQPYFSGGKVIGQLGTESGRLSEEA
DCIRQELQADLGLAVSVLIKPESTEDNVLAKVYLTLATTSGISQKEIDLGGYSWQYLRQLACLQAWDFVRNTL

Nucleotide


Download         Length: 1182 bp        

>NTDB_id=180656 A6M16_RS00380 WP_044685818.1 64492..65673(+) (cinA) [Streptococcus suis strain DN13]
ATGAAAGCAGAACTAATCGCCGTTGGGACGGAGATTTTGACAGGTCAAATCATTAATACCAATGCTCAGTTCCTTTCGGA
GAAATGTGCAGAGCTGGGAATTGATGTTTATTTCCACACAGCTGTTGGAGATAATGAAAACAGGCTTCTGTCTGTACTGG
AAGTAGCCAGTCAGCGGAGCGACTTGGTCATTCTCTGTGGAGGACTTGGTCCAACTGAGGATGACTTGACCAAGCAGACC
CTGGCGACCTTCTTAGGTAGAAATCTTGTGTTTGATGAGTTGGCTATGGCAAAATTAGACCGTTTCTTTGCCAGTCGTCC
AGGTCGTGTCCGTACACCAAATAATGAACGTCAGGCACAGATTGTGGAGGGAAGTCAGGCGCTACAGAATCCAGCTGGTT
TAGCTGTTGGTGGTATGATTGAGCAAGATGGTGTAACCTATATTGTTTTGCCTGGCCCACCAAGTGAGCTCAAGGCCATG
TTTTCTGAGAGTCTCTTACCTTTACTGTCCCAATCTCAGCAGCAACTTTATTCGCGTGTCCTACGTTTTTTTAGCATTGG
CGAAAGCCAGTTGGTGACTGTTTTGGCGGACTTGATTGACAAGCAGACAGACCCAACTCTTGCTCCTTATGCAAAAGTTG
GAGAGGTGACTTTACGCTTGTCCACCAAAGCGACCAGCCAAGAAGAAGCAAATCTACGTTTGAATCAGTTGGAAGAAGAA
ATCTTACAACATGACAAACTGGCAGACTATTTCTATGCCTACGGAGAGGACAATAGTTTGGTCAAAACGGTAGCGACTCG
TTTGGCGGAGAAAAGACAAACCATCGCTATCGTCGAACAGGGGACAGGTGGTCTCTTGCAAGCTGAATTGAGCCTGGCTT
TGGCTGATCAGCCGTATTTTAGCGGAGGAAAAGTCATCGGTCAGCTAGGGACAGAATCGGGCAGGCTATCAGAGGAAGCT
GACTGCATTCGGCAGGAGCTGCAAGCTGATTTGGGTTTGGCTGTGTCTGTGCTTATCAAACCGGAATCAACAGAGGACAA
CGTACTTGCAAAAGTATATCTCACTTTGGCTACGACCTCGGGTATTTCCCAAAAAGAGATAGATTTAGGTGGTTATTCGT
GGCAATACCTTCGCCAGCTTGCTTGTCTGCAGGCCTGGGATTTTGTACGAAACACTTTGTGA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus suis isolate S10

96.692

100

0.967
  cinA Streptococcus pneumoniae R6

56.01

100

0.593
  cinA Streptococcus mitis SK321

56.01

100

0.593
  cinA Streptococcus pneumoniae TIGR4

56.01

100

0.593
  cinA Streptococcus pneumoniae Rx1

56.01

100

0.593
  cinA Streptococcus mutans UA159

56.691

100

0.593
  cinA Streptococcus mitis NCTC 12261

55.769

100

0.59
  cinA Streptococcus pneumoniae D39

55.769

100

0.59
  cinA Bacillus subtilis subsp. subtilis str. 168

40.921

99.491

0.407

Multiple sequence alignment