Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   NX99_RS01425 Genome accession   NZ_CP015282
Coordinates   399261..400100 (+) Length   279 a.a.
NCBI ID   WP_048790506.1    Uniprot ID   -
Organism   Streptococcus salivarius strain ATCC 27945     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 394261..405100
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NX99_RS01395 (NX99_01385) - 394678..395205 (+) 528 WP_002883896.1 ECF transporter S component -
  NX99_RS01400 (NX99_01390) - 395228..395740 (+) 513 WP_070577338.1 transcription repressor NadR -
  NX99_RS01405 (NX99_01395) - 395838..396527 (+) 690 WP_049553740.1 XRE family transcriptional regulator -
  NX99_RS01410 (NX99_01400) ylqF 396656..397510 (+) 855 WP_014634567.1 ribosome biogenesis GTPase YlqF -
  NX99_RS01415 (NX99_01405) - 397497..398267 (+) 771 WP_048790508.1 ribonuclease HII -
  NX99_RS01420 (NX99_01410) - 398274..399194 (+) 921 WP_048790507.1 ROK family protein -
  NX99_RS01425 (NX99_01415) dprA 399261..400100 (+) 840 WP_048790506.1 DNA-processing protein DprA Machinery gene
  NX99_RS01430 (NX99_01420) topA 400268..402409 (+) 2142 WP_049545392.1 type I DNA topoisomerase -
  NX99_RS01435 (NX99_01425) - 402590..403264 (+) 675 WP_070438352.1 ABC transporter ATP-binding protein -
  NX99_RS01440 (NX99_01430) - 403269..403991 (+) 723 WP_198158259.1 lantibiotic ABC transporter permease -
  NX99_RS01445 (NX99_01435) - 403985..404635 (+) 651 WP_045768655.1 nisG -

Sequence

Protein


Download         Length: 279 a.a.        Molecular weight: 31357.30 Da        Isoelectric Point: 8.6687

>NTDB_id=178198 NX99_RS01425 WP_048790506.1 399261..400100(+) (dprA) [Streptococcus salivarius strain ATCC 27945]
MNHFELFKLKSAGLTNLNILNILDYQETQDRKLSLRDMAVVSKSKNAVLFMEKYKNLDVKQLREQFKRFPTLSIFDKEYP
IELKHTYNPPVLLFYQGNLDLLSKPKLAVVGARKCSETGKQSVRKIVSELGNHFTIVSGLARGIDTCAHMEALKNKGNTI
AVIGTGLDVYYPKENKALQDYMAKNHLVLTEYGPGEQPLKYHFPERNRIISGLCQGVMVVEAKLRSGSLITCERAMEEGR
DVFAIPGNILDGKSDGCHHLIQEGAKCITTGFDILSEFS

Nucleotide


Download         Length: 840 bp        

>NTDB_id=178198 NX99_RS01425 WP_048790506.1 399261..400100(+) (dprA) [Streptococcus salivarius strain ATCC 27945]
ATGAACCACTTTGAACTTTTTAAACTGAAATCTGCTGGGTTGACGAATTTGAATATCTTAAATATTTTAGACTATCAAGA
AACTCAAGATAGAAAATTAAGTCTGCGTGATATGGCAGTTGTCTCTAAGTCTAAAAATGCTGTTCTCTTTATGGAGAAAT
ACAAGAATTTGGATGTCAAGCAACTGAGAGAGCAGTTTAAACGTTTTCCTACACTCTCAATTTTTGATAAGGAGTATCCC
ATTGAGCTAAAGCATACCTATAATCCCCCTGTTCTCTTATTTTATCAAGGAAATCTTGATCTCTTGAGTAAGCCAAAATT
AGCTGTTGTTGGGGCAAGAAAGTGTTCTGAAACAGGCAAACAGTCCGTTCGAAAAATTGTTAGTGAACTTGGGAATCACT
TTACTATTGTTAGTGGATTGGCGCGTGGGATTGATACTTGTGCGCATATGGAAGCCTTGAAAAATAAAGGCAACACTATT
GCAGTTATCGGGACAGGACTTGATGTTTATTATCCTAAAGAAAATAAAGCTTTGCAGGACTATATGGCAAAAAATCATTT
AGTTCTTACAGAATATGGACCAGGTGAACAGCCTCTCAAGTACCACTTTCCTGAACGCAATCGGATTATTTCTGGATTGT
GTCAAGGAGTTATGGTTGTAGAAGCTAAGCTTCGCTCAGGAAGTCTGATTACTTGTGAGCGTGCCATGGAAGAAGGTAGA
GATGTTTTTGCTATTCCAGGAAATATTTTAGATGGCAAGTCAGATGGATGCCATCACCTAATTCAGGAGGGCGCAAAGTG
CATTACGACAGGGTTTGACATCCTTTCAGAGTTTTCTTGA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(71-269)

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(1-62)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Streptococcus mutans UA159

73.118

100

0.731
  dprA/cilB/dalA Streptococcus mitis SK321

64.029

99.642

0.638
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

63.669

99.642

0.634
  dprA/cilB/dalA Streptococcus pneumoniae D39

63.669

99.642

0.634
  dprA/cilB/dalA Streptococcus pneumoniae R6

63.669

99.642

0.634
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

63.669

99.642

0.634
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

63.309

99.642

0.631
  dprA Lactococcus lactis subsp. cremoris KW2

61.151

99.642

0.609
  dprA Acinetobacter baumannii D1279779

46.903

81.004

0.38
  dprA Acinetobacter baumannii strain A118

46.903

81.004

0.38
  dprA Latilactobacillus sakei subsp. sakei 23K

40.541

92.832

0.376
  dprA Bacillus subtilis subsp. subtilis str. 168

48.571

75.269

0.366
  dprA Glaesserella parasuis strain SC1401

39.08

93.548

0.366

Multiple sequence alignment