Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   BTR42_RS00635 Genome accession   NZ_CP018822
Coordinates   95276..96217 (+) Length   313 a.a.
NCBI ID   WP_077495921.1    Uniprot ID   -
Organism   Streptococcus gallolyticus subsp. gallolyticus DSM 16831     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 90276..101217
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BTR42_RS00625 (BTR42_00390) rpoC 91028..94666 (+) 3639 WP_012961326.1 DNA-directed RNA polymerase subunit beta' -
  BTR42_RS00630 (BTR42_00395) - 94837..95205 (+) 369 WP_074658936.1 DUF1033 family protein -
  BTR42_RS00635 (BTR42_00400) comGA 95276..96217 (+) 942 WP_077495921.1 competence type IV pilus ATPase ComGA Machinery gene
  BTR42_RS00640 (BTR42_00405) comGB 96099..97184 (+) 1086 WP_231873059.1 competence type IV pilus assembly protein ComGB Machinery gene
  BTR42_RS00645 (BTR42_00410) comGC 97184..97477 (+) 294 WP_039695588.1 competence type IV pilus major pilin ComGC Machinery gene
  BTR42_RS00650 (BTR42_00415) comGD 97461..97892 (+) 432 WP_009853232.1 competence type IV pilus minor pilin ComGD Machinery gene
  BTR42_RS00655 (BTR42_00420) comGE 97846..98139 (+) 294 WP_012961329.1 competence type IV pilus minor pilin ComGE Machinery gene
  BTR42_RS00660 (BTR42_00425) comGF 98093..98560 (+) 468 WP_012961330.1 competence type IV pilus minor pilin ComGF Machinery gene
  BTR42_RS00665 (BTR42_00430) comGG 98514..98864 (+) 351 WP_420031090.1 competence type IV pilus minor pilin ComGG Machinery gene
  BTR42_RS00670 (BTR42_00435) comGH 98919..99875 (+) 957 WP_009853236.1 class I SAM-dependent methyltransferase Machinery gene
  BTR42_RS00675 (BTR42_00440) - 99928..101127 (+) 1200 WP_061458770.1 acetate kinase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35757.94 Da        Isoelectric Point: 5.4957

>NTDB_id=176148 BTR42_RS00635 WP_077495921.1 95276..96217(+) (comGA) [Streptococcus gallolyticus subsp. gallolyticus DSM 16831]
MIQEKAKQLIKEAVEVNAQDIYILPREDCYEVYQRVGDQRQFVDYFELEQMTSLISHFKFVAGMNVGEKRRSQLGSCDYQ
FADEEEISLRLSSVGDYRGRESLVIRLLYSGRHDLQYWFDGMKNILEAIDSRGLYLFSGPVGSGKTTLMYQLVREKFPNK
QVITIEDPVEIKQEQMLQLQLNSDIGMTYDELIKLSLRHRPDILIIGEIRDSETARAVIRASLTGAVVFSTIHAKSIPGV
YARLLELGVSKQELENSLRAIVYQRLIGGGGVIDFAKENFESHRPECWNTKIESLVKDGHITAEQAKIEKIAI

Nucleotide


Download         Length: 942 bp        

>NTDB_id=176148 BTR42_RS00635 WP_077495921.1 95276..96217(+) (comGA) [Streptococcus gallolyticus subsp. gallolyticus DSM 16831]
ATGATTCAGGAAAAAGCAAAGCAACTCATTAAGGAGGCTGTTGAAGTTAATGCGCAAGATATTTACATTTTACCTAGAGA
AGACTGTTATGAAGTGTATCAACGCGTGGGAGACCAACGGCAATTTGTTGATTATTTTGAGCTAGAGCAGATGACTAGCT
TGATTAGTCATTTTAAATTTGTGGCTGGTATGAATGTTGGGGAGAAACGTCGCAGCCAGCTAGGTTCTTGTGATTATCAA
TTTGCAGATGAGGAAGAGATTTCGCTTCGTTTGTCGAGTGTTGGTGATTATCGTGGACGAGAAAGTTTAGTGATTCGCTT
GCTTTATTCTGGTCGTCATGATTTACAATATTGGTTTGACGGGATGAAAAATATTTTAGAAGCCATTGATAGTAGGGGGC
TTTACCTTTTTTCGGGACCAGTAGGGAGTGGAAAAACCACTCTCATGTACCAATTGGTTCGTGAAAAATTTCCTAATAAG
CAAGTCATTACAATTGAGGACCCTGTTGAAATCAAACAGGAACAAATGTTGCAGTTGCAGTTAAATAGTGATATTGGGAT
GACTTATGACGAGCTGATTAAATTATCGCTTCGCCATAGACCAGATATTCTGATTATCGGAGAAATTCGTGATAGCGAGA
CAGCGCGTGCAGTTATTCGTGCGAGTTTGACGGGAGCTGTTGTATTTTCGACTATTCATGCGAAGAGCATCCCTGGCGTT
TACGCACGTCTTTTGGAATTAGGGGTTAGTAAGCAAGAATTGGAAAATAGTTTGCGTGCCATTGTTTATCAACGCTTAAT
TGGCGGAGGAGGTGTGATTGATTTTGCTAAAGAAAACTTTGAAAGTCACCGACCAGAGTGCTGGAATACAAAAATTGAAA
GTCTTGTTAAAGACGGACATATCACAGCTGAACAAGCAAAAATCGAAAAAATTGCCATTTAA

Domains

Predicted by InterProScan.

Type II/IV secretion system protein (T2SSE)

(8-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Streptococcus mutans UA159

69.453

99.361

0.69
  comGA Streptococcus mutans UA140

69.132

99.361

0.687
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

67.419

99.042

0.668
  comGA Streptococcus gordonii str. Challis substr. CH1

65.595

99.361

0.652
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

62.821

99.681

0.626
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

62.5

99.681

0.623
  comGA/cglA/cilD Streptococcus pneumoniae D39

62.5

99.681

0.623
  comGA/cglA/cilD Streptococcus pneumoniae R6

62.5

99.681

0.623
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

62.5

99.681

0.623
  comGA Lactococcus lactis subsp. cremoris KW2

54.952

100

0.55
  comGA Latilactobacillus sakei subsp. sakei 23K

43.116

88.179

0.38