Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   A0V43_RS03610 Genome accession   NZ_CP014749
Coordinates   708971..710215 (+) Length   414 a.a.
NCBI ID   WP_063192397.1    Uniprot ID   A0A142CZK7
Organism   Geobacillus sp. JS12     
Function   unknown (predicted from homology)   
Unclear

Genomic Context

Location: 703971..715215
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A0V43_RS03580 (A0V43_03580) - 704070..705359 (+) 1290 WP_015374445.1 pitrilysin family protein -
  A0V43_RS03585 (A0V43_03585) - 705414..706130 (+) 717 WP_063192396.1 SDR family oxidoreductase -
  A0V43_RS03590 (A0V43_03590) - 706193..706441 (+) 249 WP_011230790.1 DUF3243 domain-containing protein -
  A0V43_RS03595 (A0V43_03595) - 706573..707364 (+) 792 WP_015374447.1 DUF3388 domain-containing protein -
  A0V43_RS03600 (A0V43_03600) - 707392..708285 (+) 894 WP_060788131.1 RodZ domain-containing protein -
  A0V43_RS03605 (A0V43_03605) pgsA 708366..708944 (+) 579 WP_025951137.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  A0V43_RS03610 (A0V43_03610) cinA 708971..710215 (+) 1245 WP_063192397.1 competence/damage-inducible protein A Machinery gene
  A0V43_RS03615 (A0V43_03615) - 710393..710679 (+) 287 Protein_754 DNA recombination/repair protein RecA -
  A0V43_RS03620 (A0V43_03620) ltrA 711516..713330 (+) 1815 WP_020278219.1 group II intron reverse transcriptase/maturase -
  A0V43_RS03625 (A0V43_03625) recA 713403..714218 (+) 816 WP_021322290.1 recombinase RecA Machinery gene

Sequence

Protein


Download         Length: 414 a.a.        Molecular weight: 44782.52 Da        Isoelectric Point: 6.0113

>NTDB_id=173584 A0V43_RS03610 WP_063192397.1 708971..710215(+) (cinA) [Geobacillus sp. JS12]
MNAEIIAVGSELLLGQIANTNAQFLSQQLAMLGINVYFHTVVGDNAGRLEQAVKTAQTRANLIIFTGGLGPTKDDLTKET
IARLLGRRLVIDEEALRAIEAYFARTNRPMTENNKKQALVLEGSTVLKNEHGMAPGMALVADGITYMLLPGPPKEMRPMF
KKYGNAFLRRTFSLSERIESRVLRFFGIGESALETAIADLIDAQSNPTIAPLAGDGEVTLRLTAKHQDEAEAKRLLDEVE
AAILARVGRHCYGYNDETLFTKTLERLKERGWTIASAESLTGGLFLEQLTAVPGASQVVQGGVVCYTNGVKEQVLGIPRP
LLEAEGAVSEPCARLLAENVRAMCDADIGISFTGVAGPDPLEGHPPGTVYIGIAVRGRDATVHRLTLSGTRDAIRIRTAK
YGCFFLLEMLAADC

Nucleotide


Download         Length: 1245 bp        

>NTDB_id=173584 A0V43_RS03610 WP_063192397.1 708971..710215(+) (cinA) [Geobacillus sp. JS12]
TTGAACGCGGAGATCATTGCCGTTGGCTCCGAGCTGTTGCTTGGGCAAATCGCCAATACGAACGCCCAGTTTTTGTCGCA
GCAGCTGGCGATGCTTGGCATTAACGTCTATTTCCATACCGTCGTCGGCGACAACGCCGGCCGCCTCGAACAGGCGGTGA
AAACCGCGCAAACGAGAGCGAACCTCATCATTTTCACCGGCGGCCTCGGCCCGACGAAAGACGATTTAACGAAGGAGACG
ATCGCCCGTTTGCTTGGCCGCCGACTCGTGATCGACGAGGAAGCGCTCCGAGCGATTGAGGCGTATTTTGCCCGCACAAA
CCGGCCGATGACAGAAAACAATAAAAAGCAGGCGCTCGTCTTGGAAGGATCGACGGTGCTGAAAAACGAGCACGGCATGG
CGCCAGGGATGGCGCTTGTGGCAGACGGCATTACGTACATGTTGCTGCCCGGGCCGCCGAAAGAAATGCGGCCGATGTTC
AAAAAATACGGAAACGCCTTTTTGCGCCGTACGTTTTCGCTTTCCGAGCGCATCGAGTCGCGCGTGCTCCGCTTTTTTGG
CATCGGTGAATCAGCGCTCGAGACGGCGATTGCGGATTTGATCGACGCCCAGTCGAATCCGACGATCGCGCCGCTGGCCG
GCGACGGTGAAGTGACGCTTCGTCTGACAGCGAAGCATCAGGATGAGGCGGAGGCGAAGCGGCTTCTTGACGAAGTGGAA
GCGGCCATTTTGGCGCGCGTCGGCCGCCACTGCTACGGATATAACGATGAAACGTTGTTTACAAAGACGCTCGAGCGGTT
AAAAGAAAGAGGATGGACGATCGCGTCGGCCGAAAGTTTGACCGGCGGCCTTTTCCTCGAACAGCTCACCGCCGTCCCCG
GCGCGTCTCAAGTCGTGCAGGGCGGTGTCGTCTGCTACACAAACGGCGTCAAAGAACAGGTGCTTGGCATACCGCGCCCG
CTGCTTGAGGCAGAAGGGGCGGTGAGCGAGCCGTGCGCCCGTTTGCTTGCTGAAAACGTCCGCGCGATGTGCGATGCGGA
TATCGGCATCAGCTTCACCGGCGTCGCCGGACCCGATCCGCTTGAGGGCCACCCGCCCGGCACCGTGTATATCGGCATCG
CCGTCCGCGGGCGCGATGCGACTGTCCACCGTCTGACGCTGTCCGGCACGCGTGATGCCATTCGCATCCGCACCGCCAAA
TACGGCTGTTTTTTTCTGCTTGAGATGCTCGCGGCCGACTGCTGA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(258-409)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-167)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A142CZK7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Bacillus subtilis subsp. subtilis str. 168

59.902

98.792

0.592
  cinA Streptococcus mitis SK321

50.653

92.512

0.469
  cinA Streptococcus mitis NCTC 12261

50.653

92.512

0.469
  cinA Streptococcus pneumoniae TIGR4

50.392

92.512

0.466
  cinA Streptococcus pneumoniae Rx1

50.392

92.512

0.466
  cinA Streptococcus pneumoniae R6

50.392

92.512

0.466
  cinA Streptococcus pneumoniae D39

50.131

92.512

0.464
  cinA Streptococcus mutans UA159

47.87

96.377

0.461
  cinA Streptococcus suis isolate S10

42.593

91.304

0.389

Multiple sequence alignment