Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   A0O21_RS09300 Genome accession   NZ_CP014699
Coordinates   2017457..2018716 (-) Length   419 a.a.
NCBI ID   WP_067064536.1    Uniprot ID   A0A172Q9S9
Organism   Streptococcus pantholopis strain TA 26     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2012457..2023716
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A0O21_RS09265 (A0O21_09265) - 2012839..2013144 (-) 306 WP_067064522.1 DUF1292 domain-containing protein -
  A0O21_RS09270 (A0O21_09270) ruvX 2013200..2013619 (-) 420 WP_067064524.1 Holliday junction resolvase RuvX -
  A0O21_RS09275 (A0O21_09275) - 2013616..2013885 (-) 270 WP_067064526.1 IreB family regulatory phosphoprotein -
  A0O21_RS09280 (A0O21_09280) - 2014154..2014594 (+) 441 WP_067064528.1 LytTR family DNA-binding domain-containing protein -
  A0O21_RS09285 (A0O21_09285) - 2014745..2015203 (+) 459 WP_067064530.1 DUF3021 domain-containing protein -
  A0O21_RS09290 (A0O21_09290) spx 2015336..2015734 (-) 399 WP_067064532.1 transcriptional regulator Spx -
  A0O21_RS09295 (A0O21_09295) recA 2016150..2017304 (-) 1155 WP_067064534.1 recombinase RecA Machinery gene
  A0O21_RS09300 (A0O21_09300) cinA 2017457..2018716 (-) 1260 WP_067064536.1 competence/damage-inducible protein A Machinery gene
  A0O21_RS09305 (A0O21_09305) - 2018830..2019414 (-) 585 WP_067064538.1 DNA-3-methyladenine glycosylase I -
  A0O21_RS09310 (A0O21_09310) ruvA 2019527..2020117 (-) 591 WP_067064540.1 Holliday junction branch migration protein RuvA -
  A0O21_RS09315 (A0O21_09315) mutL 2020130..2022067 (-) 1938 WP_067064542.1 DNA mismatch repair endonuclease MutL -

Sequence

Protein


Download         Length: 419 a.a.        Molecular weight: 45494.91 Da        Isoelectric Point: 4.9602

>NTDB_id=173376 A0O21_RS09300 WP_067064536.1 2017457..2018716(-) (cinA) [Streptococcus pantholopis strain TA 26]
MKAEIIAVGTELLTGQIVNTNAQFLSEKFAELGIDVFYQTVVGDNENRLLSVIDIASSRSNLVVLCGGLGPTDDDLTKQT
LAKYLGRHLEFDEQAVQRLDAFFATRPQFTRTPNNERQAQLIAGSVPLQNTTGLAVGGIIEQNAVTYVVLPGPPSELIPM
VTDQLVPYLTQSNQRLYSRVLRFFGIGESQLVTVLADVIKDQTDPTIAPYAKTGEVTLRLSTKAVSEEAAGLKLDKLEER
IMAIKTLDGVSLSDLHYGYGDDNSLARTAFDLLKEKGKTVTAAESLTAGLFQASLAEFSGASQVFSGGFVTYSMEEKAKM
LKIPLTDLQAHGVVSAFTAEKMADQARKLTDSDFGLGLTGVAGPQELEKQPAGTVFIGFASKEKVYSLKLELGSRSRSDI
RYITVLHAFNLIRQTLLKD

Nucleotide


Download         Length: 1260 bp        

>NTDB_id=173376 A0O21_RS09300 WP_067064536.1 2017457..2018716(-) (cinA) [Streptococcus pantholopis strain TA 26]
ATGAAAGCAGAAATTATTGCGGTAGGAACCGAGCTGCTGACGGGGCAGATTGTAAATACCAATGCCCAATTTTTATCTGA
AAAGTTTGCTGAATTAGGGATTGACGTTTTTTATCAGACAGTTGTCGGCGATAATGAGAACCGCCTTTTGTCTGTCATTG
ATATTGCCAGCAGCCGCAGCAACCTTGTTGTACTTTGCGGCGGGCTTGGGCCGACCGATGATGATTTGACGAAACAGACT
CTGGCAAAGTATTTAGGCCGGCATCTGGAGTTTGATGAACAAGCTGTGCAGCGTTTAGATGCATTTTTTGCAACACGCCC
CCAATTTACCAGAACTCCAAATAATGAGAGGCAGGCCCAGCTGATTGCAGGCTCCGTTCCACTGCAGAATACAACAGGTT
TAGCGGTCGGAGGAATCATCGAACAGAACGCAGTCACATACGTCGTACTTCCGGGACCTCCAAGTGAGCTGATTCCGATG
GTTACAGATCAGCTTGTCCCCTATTTAACTCAGTCCAATCAGCGGCTCTACTCGCGTGTTTTGCGTTTCTTCGGTATCGG
TGAAAGCCAGCTGGTGACTGTTTTAGCAGATGTTATTAAAGATCAGACTGATCCGACCATTGCTCCTTATGCAAAAACCG
GCGAAGTGACTTTGCGCTTATCCACTAAAGCGGTCAGTGAGGAGGCAGCCGGCCTTAAACTCGACAAGCTTGAAGAGCGG
ATTATGGCTATAAAAACACTGGATGGTGTGAGTCTGAGCGACTTACACTATGGTTATGGTGATGATAATAGCTTGGCTCG
TACGGCCTTTGACCTCCTTAAGGAGAAAGGAAAGACCGTAACAGCGGCCGAAAGCCTTACAGCCGGCCTGTTTCAGGCGA
GTTTAGCAGAATTTTCCGGGGCTTCGCAGGTTTTTAGCGGGGGTTTTGTAACCTACAGTATGGAAGAAAAAGCAAAAATG
CTGAAAATTCCCCTTACAGACTTACAGGCTCATGGTGTAGTCAGCGCCTTTACTGCTGAAAAAATGGCCGACCAGGCCCG
GAAACTGACAGATTCGGATTTTGGCTTGGGTCTGACTGGTGTTGCCGGACCTCAAGAATTGGAAAAACAGCCGGCAGGTA
CTGTTTTTATCGGTTTTGCAAGTAAAGAAAAAGTCTATTCGCTTAAGCTGGAGCTAGGAAGCCGAAGCCGTTCGGACATA
CGCTATATCACAGTACTGCACGCTTTCAATTTGATACGCCAAACTTTATTAAAAGACTGA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-243)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Competence-damaged protein (CinA)

(263-416)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A172Q9S9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

70.024

99.523

0.697
  cinA Streptococcus mitis SK321

67.78

100

0.678
  cinA Streptococcus mitis NCTC 12261

67.78

100

0.678
  cinA Streptococcus pneumoniae TIGR4

66.11

100

0.661
  cinA Streptococcus pneumoniae Rx1

66.11

100

0.661
  cinA Streptococcus pneumoniae R6

66.11

100

0.661
  cinA Streptococcus pneumoniae D39

65.871

100

0.659
  cinA Streptococcus suis isolate S10

54.567

99.284

0.542
  cinA Bacillus subtilis subsp. subtilis str. 168

45.952

100

0.461

Multiple sequence alignment