Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   AVL55_RS15160 Genome accession   NZ_CP014323
Coordinates   3419921..3421129 (+) Length   402 a.a.
NCBI ID   WP_061095699.1    Uniprot ID   A0A126Q274
Organism   Alteromonas macleodii strain D7     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 3414921..3426129
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AVL55_RS15135 (AVL55_15135) ampE 3415762..3416664 (-) 903 WP_061095694.1 beta-lactamase regulator AmpE -
  AVL55_RS15140 (AVL55_15140) ampD 3416708..3417247 (-) 540 WP_061095695.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  AVL55_RS15145 (AVL55_15145) - 3417431..3417949 (+) 519 WP_061095696.1 retropepsin-like aspartic protease family protein -
  AVL55_RS15150 (AVL55_15150) nadC 3417982..3418836 (+) 855 WP_061095697.1 carboxylating nicotinate-nucleotide diphosphorylase -
  AVL55_RS15155 (AVL55_15155) - 3419407..3419844 (+) 438 WP_061095698.1 pilin -
  AVL55_RS15160 (AVL55_15160) pilC 3419921..3421129 (+) 1209 WP_061095699.1 type II secretion system F family protein Machinery gene
  AVL55_RS15165 (AVL55_15165) pilD 3421182..3422075 (+) 894 WP_061095700.1 prepilin peptidase Machinery gene
  AVL55_RS15170 (AVL55_15170) coaE 3422094..3422705 (+) 612 WP_061095701.1 dephospho-CoA kinase -
  AVL55_RS15175 (AVL55_15175) zapD 3422949..3423701 (+) 753 WP_061095702.1 cell division protein ZapD -
  AVL55_RS15180 (AVL55_15180) yacG 3423835..3424062 (+) 228 WP_014980027.1 DNA gyrase inhibitor YacG -
  AVL55_RS15185 (AVL55_15185) - 3424282..3425154 (+) 873 WP_061095703.1 aspartoacylase -
  AVL55_RS15190 (AVL55_15190) mutT 3425274..3425657 (-) 384 WP_061095704.1 8-oxo-dGTP diphosphatase MutT -

Sequence

Protein


Download         Length: 402 a.a.        Molecular weight: 43757.44 Da        Isoelectric Point: 9.6772

>NTDB_id=170326 AVL55_RS15160 WP_061095699.1 3419921..3421129(+) (pilC) [Alteromonas macleodii strain D7]
MAKTTASFTWQGKDRHGQARKGEISATSLSEAKNLLRRQGISANKVKRLTKPLFGGSKKITPADISVVSRQIATMLAAGV
TLIQSLDMIAQGHANPTMRKLLGEITDEVKSGNPLSSALRKHPLYFDDLYCDLVYTGEQSGALETIYDRIATYKEKAEAL
KSKIKKAMFYPIAVLVVAFIVTTILLIFVVPQFEEIFSSFGAELPAFTQFVLAISRFVQDYGIFIAIGIGGAGFMFMRTY
KRSQKLRDTVDRNILKIPVIGEILKKASIARFTRTLATTFAAGVPLIGALESAAGASGNAVYREAILYMRKEVAGGMPMH
VAMRATQVFPDMVTQMIAIGEESGAVDEMLSKIATIYEAEVDDMVDGLTSLLEPMIMAILGVVIGGLIVAMYLPIFQMGN
VV

Nucleotide


Download         Length: 1209 bp        

>NTDB_id=170326 AVL55_RS15160 WP_061095699.1 3419921..3421129(+) (pilC) [Alteromonas macleodii strain D7]
ATGGCAAAAACAACCGCATCTTTTACTTGGCAAGGCAAAGACCGCCACGGCCAAGCTCGAAAAGGTGAAATATCAGCGAC
TTCGCTTTCAGAAGCAAAGAATCTTCTTCGCCGCCAAGGCATCTCTGCAAATAAAGTAAAAAGACTTACCAAACCGCTTT
TTGGCGGATCAAAAAAAATTACGCCAGCTGATATTTCCGTTGTTTCGCGGCAGATTGCGACCATGCTTGCCGCAGGGGTC
ACGCTAATTCAGTCTTTGGATATGATCGCGCAAGGCCACGCCAACCCCACCATGCGTAAGCTGCTTGGTGAAATTACTGA
CGAGGTTAAATCTGGTAACCCGCTCTCATCCGCGCTCAGAAAACACCCTCTTTATTTTGACGATTTATATTGCGACTTGG
TTTATACCGGTGAGCAGTCGGGCGCACTTGAAACTATTTATGACCGCATTGCGACCTACAAAGAAAAGGCCGAAGCACTA
AAATCAAAAATCAAAAAAGCGATGTTTTACCCTATCGCAGTTTTGGTTGTTGCTTTTATTGTTACGACCATTCTTCTTAT
ATTTGTTGTACCGCAGTTTGAAGAAATTTTCAGCAGCTTTGGGGCAGAACTCCCCGCCTTCACTCAGTTCGTATTGGCTA
TTTCCCGATTTGTACAAGACTACGGTATTTTTATCGCTATAGGTATTGGTGGTGCTGGCTTTATGTTTATGCGCACCTAT
AAGCGAAGCCAGAAGCTACGTGACACGGTGGACCGCAACATTTTAAAAATTCCCGTCATTGGCGAAATATTAAAAAAAGC
CAGCATTGCGCGCTTTACCCGAACCCTAGCCACGACCTTCGCAGCAGGTGTGCCGCTTATTGGCGCACTAGAATCCGCTG
CCGGAGCTTCGGGCAACGCGGTATACCGCGAGGCCATTTTATACATGCGTAAAGAAGTGGCGGGCGGTATGCCAATGCAT
GTGGCTATGCGCGCTACACAAGTATTCCCTGACATGGTGACGCAGATGATTGCCATTGGTGAAGAGTCGGGCGCGGTTGA
TGAAATGCTCAGCAAAATTGCCACCATATACGAAGCTGAAGTCGATGATATGGTGGACGGTTTAACCAGCCTTCTAGAGC
CTATGATCATGGCCATTCTTGGCGTGGTAATCGGCGGCTTAATTGTGGCTATGTACCTCCCTATATTCCAGATGGGTAAC
GTGGTATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(69-191)

Type II secretion system (T2SS), protein F (T2SSF)

(272-394)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A126Q274

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

58.987

98.259

0.58
  pilC Acinetobacter baumannii D1279779

53.102

100

0.532
  pilC Acinetobacter baylyi ADP1

53.149

98.756

0.525
  pilC Legionella pneumophila strain ERS1305867

53.149

98.756

0.525
  pilG Neisseria meningitidis 44/76-A

45.05

100

0.453
  pilG Neisseria gonorrhoeae MS11

44.802

100

0.45
  pilC Vibrio cholerae strain A1552

45.34

98.756

0.448
  pilC Vibrio campbellii strain DS40M4

43.073

98.756

0.425
  pilC Thermus thermophilus HB27

37

99.502

0.368

Multiple sequence alignment