Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   AL541_RS12700 Genome accession   NZ_CP014040
Coordinates   2553030..2554253 (+) Length   407 a.a.
NCBI ID   WP_017635918.1    Uniprot ID   A0AAW9BMM9
Organism   Vibrio alginolyticus strain FDAARGOS_110     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2548030..2559253
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AL541_RS12680 (AL541_21050) ampD 2549077..2549628 (-) 552 WP_017635914.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  AL541_RS12685 (AL541_21055) nadC 2549721..2550608 (+) 888 WP_017635915.1 carboxylating nicotinate-nucleotide diphosphorylase -
  AL541_RS12690 (AL541_21060) - 2550871..2551314 (+) 444 WP_064354289.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  AL541_RS12695 (AL541_21065) pilB 2551321..2553006 (+) 1686 WP_104979679.1 type IV-A pilus assembly ATPase PilB Machinery gene
  AL541_RS12700 (AL541_21070) pilC 2553030..2554253 (+) 1224 WP_017635918.1 type II secretion system F family protein Machinery gene
  AL541_RS12705 (AL541_21075) pilD 2554318..2555187 (+) 870 WP_017635919.1 A24 family peptidase Machinery gene
  AL541_RS12710 (AL541_21080) coaE 2555188..2555802 (+) 615 WP_017635920.1 dephospho-CoA kinase -
  AL541_RS12715 (AL541_21085) zapD 2555830..2556570 (+) 741 WP_005373086.1 cell division protein ZapD -
  AL541_RS12720 (AL541_21090) yacG 2556729..2556923 (+) 195 WP_017635922.1 DNA gyrase inhibitor YacG -
  AL541_RS12725 (AL541_21095) rplS 2557578..2557931 (-) 354 WP_005379971.1 50S ribosomal protein L19 -
  AL541_RS12730 (AL541_21100) trmD 2557973..2558734 (-) 762 WP_005385420.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 45313.50 Da        Isoelectric Point: 10.3992

>NTDB_id=167829 AL541_RS12700 WP_017635918.1 2553030..2554253(+) (pilC) [Vibrio alginolyticus strain FDAARGOS_110]
MKSTTPQLKNFRWKGINSSGKKTSGQTLAMTEIEVRERLDAQHIKIKKLKKSSISFLTKLSHRVKGRDITVFTRQISTML
ITGVPLVQALKLVSENHKKAEMKSILMSVTRAVEAGTPMSKAMRTASEHFDPLYTDLIATGEQSGNLAEVFERLATYREK
NEQLRAKVIKALIYPAMVVLVALGVSFIMLTKVIPEFEKMFVGFGADLPWFTRQVLDLSAWTQNWSPFIALGSISLFISA
RILSKRSDSFRLMLNRSVLKFPVLGPVLSKAAIAKFSRTLATSFTAGIPILTSLKTTSKTSGNLHYQLAIEEVYRDTAAG
MPMYVAMRNCNVFPELVLQMVMIGEESGRLDDMLNKVATIYEFEVDNTVDNLSKILEPLIIVFLGIVVGGLVTAMYLPIF
NLMSVLG

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=167829 AL541_RS12700 WP_017635918.1 2553030..2554253(+) (pilC) [Vibrio alginolyticus strain FDAARGOS_110]
ATGAAAAGCACTACACCACAACTTAAAAACTTCCGCTGGAAAGGCATCAACAGTTCTGGCAAAAAGACGTCTGGACAAAC
CCTCGCGATGACAGAAATTGAAGTACGCGAGCGTCTAGACGCACAGCACATCAAGATCAAGAAGTTAAAGAAAAGCAGTA
TCTCGTTTCTCACTAAACTCAGCCATCGCGTGAAAGGCAGAGACATCACGGTGTTTACCCGTCAGATTTCGACGATGTTG
ATAACCGGTGTACCCTTAGTTCAGGCTTTAAAATTGGTCTCAGAAAATCATAAAAAAGCAGAGATGAAATCCATTTTGAT
GAGCGTGACACGCGCCGTTGAAGCGGGGACGCCCATGTCAAAAGCCATGCGCACTGCAAGTGAACACTTTGACCCACTCT
ATACCGATCTTATCGCCACAGGTGAGCAATCCGGTAACTTAGCAGAAGTGTTCGAGCGCTTAGCCACCTACCGAGAAAAA
AATGAACAACTCCGTGCGAAAGTGATCAAAGCACTGATTTACCCAGCGATGGTAGTGCTAGTAGCGTTAGGCGTGTCGTT
TATCATGCTCACCAAAGTCATTCCCGAGTTTGAAAAAATGTTTGTTGGTTTTGGTGCTGACTTACCGTGGTTTACCAGGC
AAGTATTAGATCTTTCCGCCTGGACACAAAACTGGAGTCCGTTTATCGCACTAGGCTCCATTAGTTTATTCATTTCGGCG
AGAATCCTCTCTAAGCGTTCAGATTCTTTTCGCTTAATGCTCAACCGCTCTGTGCTTAAATTTCCTGTCCTGGGCCCTGT
ATTATCAAAAGCCGCTATCGCCAAATTTAGTCGAACACTCGCCACAAGCTTTACAGCGGGCATTCCAATTCTAACCAGTT
TAAAAACTACATCAAAAACATCAGGAAACTTGCACTATCAACTCGCCATAGAAGAAGTGTACCGTGATACCGCCGCAGGT
ATGCCAATGTATGTTGCCATGCGTAACTGTAATGTGTTCCCTGAATTAGTGTTACAAATGGTCATGATCGGTGAAGAGTC
TGGTCGACTTGACGATATGCTCAATAAAGTTGCAACGATCTACGAGTTTGAAGTCGATAACACCGTCGACAACCTTAGTA
AAATTCTAGAGCCGCTAATTATCGTTTTTTTAGGCATCGTTGTTGGCGGATTAGTGACAGCAATGTACTTGCCAATCTTT
AACTTAATGAGTGTATTGGGCTAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(72-195)

Type II secretion system (T2SS), protein F (T2SSF)

(276-398)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Vibrio campbellii strain DS40M4

87.224

100

0.872
  pilC Vibrio cholerae strain A1552

73.775

100

0.74
  pilC Acinetobacter baylyi ADP1

43

98.28

0.423
  pilC Acinetobacter baumannii D1279779

41.439

99.017

0.41
  pilG Neisseria gonorrhoeae MS11

40.494

99.509

0.403
  pilC Legionella pneumophila strain ERS1305867

40.295

100

0.403
  pilG Neisseria meningitidis 44/76-A

40.247

99.509

0.4
  pilC Pseudomonas stutzeri DSM 10701

40.909

97.297

0.398

Multiple sequence alignment