Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   WL1483_RS16640 Genome accession   NZ_CP013067
Coordinates   3474891..3476129 (+) Length   412 a.a.
NCBI ID   WP_050666599.1    Uniprot ID   A0A0S2SE58
Organism   Aeromonas schubertii strain WL1483     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 3469891..3481129
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WL1483_RS16615 (WL1483_3425) nadC 3470270..3471130 (+) 861 WP_060587253.1 carboxylating nicotinate-nucleotide diphosphorylase -
  WL1483_RS22035 tapA 3471391..3471819 (+) 429 WP_082634874.1 type IVa pilus major pilin TapA -
  WL1483_RS16620 (WL1483_4313) - 3471826..3472224 (+) 399 Protein_3239 type IV-A pilus assembly ATPase PilB -
  WL1483_RS16635 (WL1483_77) pilB 3473557..3474870 (+) 1314 Protein_3241 type IV-A pilus assembly ATPase PilB -
  WL1483_RS16640 (WL1483_553) pilC 3474891..3476129 (+) 1239 WP_050666599.1 type II secretion system F family protein Machinery gene
  WL1483_RS16645 (WL1483_3227) pilD 3476155..3477024 (+) 870 WP_060587255.1 prepilin peptidase Machinery gene
  WL1483_RS16650 (WL1483_3670) coaE 3477035..3477649 (+) 615 WP_060587256.1 dephospho-CoA kinase -
  WL1483_RS16655 (WL1483_3258) zapD 3477688..3478410 (+) 723 WP_050666596.1 cell division protein ZapD -
  WL1483_RS16660 (WL1483_3909) yacG 3478420..3478608 (+) 189 WP_050666595.1 DNA gyrase inhibitor YacG -
  WL1483_RS16665 (WL1483_2338) mutT 3478640..3479050 (-) 411 WP_050666594.1 8-oxo-dGTP diphosphatase MutT -

Sequence

Protein


Download         Length: 412 a.a.        Molecular weight: 45251.22 Da        Isoelectric Point: 9.3713

>NTDB_id=159543 WL1483_RS16640 WP_050666599.1 3474891..3476129(+) (pilC) [Aeromonas schubertii strain WL1483]
MATLAQKNKSPKISAFRWSGVNRKGQKVSGEMQADSVNTVKAELRKQGVTVSKVSKKSQGLFSKGAAKINTMDIAVITRQ
ITTMLSAGVPLVQTLQVIARSHEKATMRELVGEIAANVETGTPLSEALRQHPRQFDQLYCDLVEAGEQSGALETIFDRIA
TYREKTEALKSKIKKAMFYPTMVIIVAIVVTSILLLFVIPQFEDIFKSFGAELPAFTQFVIGISRFMQDWWYVFFGGTAL
VIFLYVRAWRASEKVRDRTDKFVLELPVVGMILHKAAMARFARTLATTFAAGIPLVDALISSAGASGNYVYRTAIMAIRN
EVIAGMQVNVAMRTVDLFPDMVIQMVMIGEESGAIDDMLSKVATIFEQEVDDLVDGLTSLLEPLIMVVLGVLVGGMVIAM
YLPIFKLGDVVG

Nucleotide


Download         Length: 1239 bp        

>NTDB_id=159543 WL1483_RS16640 WP_050666599.1 3474891..3476129(+) (pilC) [Aeromonas schubertii strain WL1483]
ATGGCAACGCTGGCTCAGAAAAATAAATCGCCCAAGATCTCCGCCTTTCGCTGGAGTGGCGTGAACCGCAAGGGACAGAA
AGTCTCCGGCGAGATGCAGGCCGACTCGGTCAATACCGTCAAGGCTGAGCTGCGCAAGCAGGGGGTGACCGTCTCCAAGG
TGAGCAAGAAGTCCCAGGGGCTCTTCTCCAAGGGCGCGGCCAAGATCAATACCATGGATATCGCCGTCATCACCCGCCAG
ATCACCACCATGCTCTCGGCCGGCGTGCCTCTGGTACAGACCCTTCAGGTCATCGCCCGCAGCCACGAGAAGGCAACCAT
GCGCGAGCTCGTCGGCGAGATCGCCGCCAATGTGGAGACGGGCACCCCCCTCTCCGAAGCCCTGCGCCAACACCCGCGCC
AGTTCGATCAGCTCTACTGCGACCTGGTGGAAGCCGGCGAACAATCGGGAGCTCTCGAGACCATTTTCGATCGCATCGCC
ACCTATCGGGAGAAGACCGAAGCACTCAAGTCGAAGATCAAGAAGGCCATGTTCTACCCCACCATGGTCATCATAGTGGC
CATCGTCGTGACCTCTATCCTGTTGTTGTTCGTCATCCCCCAGTTCGAGGATATCTTCAAGAGCTTCGGGGCCGAACTCC
CCGCCTTCACCCAGTTTGTCATCGGCATCTCACGCTTCATGCAAGACTGGTGGTATGTCTTCTTCGGCGGTACCGCCCTG
GTTATTTTCCTCTATGTGCGGGCATGGCGAGCCTCCGAGAAGGTACGAGACCGAACCGACAAGTTTGTGCTCGAGCTCCC
CGTGGTCGGCATGATACTGCACAAGGCGGCCATGGCCCGTTTTGCCCGCACCCTGGCCACCACCTTTGCCGCCGGTATCC
CGCTGGTTGACGCACTGATCTCCTCGGCCGGGGCCTCGGGCAACTATGTCTATCGCACCGCCATCATGGCCATTCGCAAC
GAAGTGATCGCCGGCATGCAGGTCAACGTCGCCATGCGCACGGTCGATCTCTTCCCCGATATGGTGATCCAGATGGTGAT
GATCGGCGAGGAATCGGGGGCCATCGATGATATGCTCTCCAAGGTCGCCACCATCTTCGAACAGGAGGTGGATGACCTCG
TCGATGGCCTGACCAGCCTGCTCGAACCCCTCATCATGGTGGTATTGGGGGTACTGGTAGGAGGCATGGTCATCGCCATG
TACCTGCCCATCTTCAAGCTGGGGGATGTGGTGGGTTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(78-200)

Type II secretion system (T2SS), protein F (T2SSF)

(281-403)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0S2SE58

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

56.576

97.816

0.553
  pilC Acinetobacter baumannii D1279779

54.167

99.029

0.536
  pilC Acinetobacter baylyi ADP1

51.852

98.301

0.51
  pilC Legionella pneumophila strain ERS1305867

51.365

97.816

0.502
  pilC Vibrio cholerae strain A1552

47.512

97.573

0.464
  pilC Vibrio campbellii strain DS40M4

45.455

98.786

0.449
  pilG Neisseria meningitidis 44/76-A

41.927

93.204

0.391
  pilG Neisseria gonorrhoeae MS11

41.927

93.204

0.391

Multiple sequence alignment