Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   EP13_RS14020 Genome accession   NZ_CP008849
Coordinates   3179765..3180976 (+) Length   403 a.a.
NCBI ID   WP_044057824.1    Uniprot ID   A0A7T0RNN2
Organism   Alteromonas australica strain H 17     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 3174765..3185976
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EP13_RS13990 (EP13_14315) pdhR 3174859..3175605 (-) 747 WP_044057818.1 pyruvate dehydrogenase complex transcriptional repressor PdhR -
  EP13_RS13995 (EP13_14320) ampE 3175943..3176812 (-) 870 WP_044057819.1 beta-lactamase regulator AmpE -
  EP13_RS14000 (EP13_14325) ampD 3176849..3177391 (-) 543 WP_044057820.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  EP13_RS14005 (EP13_14330) - 3177503..3178021 (+) 519 WP_044057821.1 TIGR02281 family clan AA aspartic protease -
  EP13_RS14010 (EP13_14335) nadC 3178040..3178903 (+) 864 WP_044057822.1 carboxylating nicotinate-nucleotide diphosphorylase -
  EP13_RS14015 (EP13_14340) - 3179219..3179650 (+) 432 WP_044057823.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  EP13_RS14020 (EP13_14345) pilC 3179765..3180976 (+) 1212 WP_044057824.1 type II secretion system F family protein Machinery gene
  EP13_RS14025 (EP13_14350) pilD 3181076..3181957 (+) 882 WP_044057825.1 A24 family peptidase Machinery gene
  EP13_RS14030 (EP13_14355) coaE 3181957..3182565 (+) 609 WP_044057826.1 dephospho-CoA kinase -
  EP13_RS14035 (EP13_14360) zapD 3182695..3183447 (+) 753 WP_044057827.1 cell division protein ZapD -
  EP13_RS14040 (EP13_14365) yacG 3183484..3183711 (+) 228 WP_044057828.1 DNA gyrase inhibitor YacG -

Sequence

Protein


Download         Length: 403 a.a.        Molecular weight: 43368.89 Da        Isoelectric Point: 9.7304

>NTDB_id=124753 EP13_RS14020 WP_044057824.1 3179765..3180976(+) (pilC) [Alteromonas australica strain H 17]
MAKAATTYTWQGKDRRGNSRKGEISAISLAEAKNLLRRQGISANKVKKLATPLFGRGAQKIVAADISVMSRQIATMLGAG
VTLIQSLDMIAQGHAKASMRKLLHEISNEVKSGNPLSGALRKHPDYFDDLYCDLVYTGEQSGALETIYDRIATYKEKAEA
LKSKIKKAMLYPIAVVVVAFVVTTILLIFVVPQFEDIFSSFGAELPAFTQFVLAISRFVQDYGFVMAIAAVGAGMLFVRA
HKKSQSLRDNVDKAILKAPVVGEILKKASIARFTRTLATTFSAGVPLIGALESAAGASGNAVFRDAILFMRKEVAGGMQM
HTAMRATNVFPDMVTQMVAIGEESGAVDSMLSKIATIYEAEVDDMVDGLTSLLEPIIMAVLGVVIGGLIVAMYLPIFEMG
NVV

Nucleotide


Download         Length: 1212 bp        

>NTDB_id=124753 EP13_RS14020 WP_044057824.1 3179765..3180976(+) (pilC) [Alteromonas australica strain H 17]
ATGGCGAAGGCAGCAACCACCTATACTTGGCAAGGCAAAGATCGCCGAGGTAACAGCAGAAAAGGCGAAATTTCTGCTAT
TAGCCTTGCCGAAGCTAAAAACCTTTTGCGACGCCAGGGCATTTCTGCCAATAAAGTGAAAAAGCTGGCTACACCGCTAT
TTGGCAGAGGCGCACAAAAGATAGTAGCTGCCGATATTTCTGTGATGTCGCGGCAAATTGCCACCATGTTAGGGGCCGGT
GTTACCCTAATTCAATCATTAGACATGATAGCGCAAGGCCATGCTAAAGCGTCTATGCGTAAGCTGCTTCACGAAATATC
TAACGAAGTTAAATCGGGAAACCCTTTGTCTGGCGCGTTACGTAAACACCCTGATTATTTCGATGATCTATACTGTGATT
TGGTTTACACAGGGGAGCAATCGGGTGCCCTTGAAACCATTTACGACCGTATAGCCACTTATAAAGAAAAGGCCGAAGCC
CTTAAATCAAAAATAAAAAAAGCCATGCTTTACCCCATCGCGGTGGTAGTGGTTGCATTTGTGGTAACCACCATTCTTTT
AATATTTGTGGTGCCACAATTTGAAGATATTTTCAGTAGCTTTGGTGCAGAGTTGCCTGCCTTTACCCAATTCGTATTAG
CCATTTCCCGTTTTGTGCAAGATTATGGATTCGTGATGGCCATTGCTGCGGTAGGCGCAGGCATGCTATTTGTGCGTGCC
CATAAAAAAAGCCAATCCCTAAGAGACAATGTAGATAAGGCCATTCTCAAAGCCCCCGTAGTGGGCGAAATACTGAAAAA
GGCCAGCATTGCGCGTTTTACCCGAACCTTGGCCACCACCTTTTCTGCTGGTGTTCCACTGATTGGCGCATTAGAGTCTG
CCGCAGGCGCTTCAGGTAATGCGGTATTTCGCGATGCCATTTTATTTATGCGCAAAGAGGTAGCGGGCGGCATGCAGATG
CATACTGCCATGCGCGCCACCAATGTATTCCCCGATATGGTGACGCAAATGGTGGCGATTGGCGAGGAGTCTGGCGCGGT
AGATAGCATGCTTAGCAAAATAGCCACTATTTATGAGGCTGAAGTCGACGATATGGTTGATGGACTAACAAGTTTACTTG
AGCCTATTATTATGGCGGTGCTGGGTGTCGTTATTGGGGGCTTAATTGTGGCCATGTACCTGCCTATATTTGAAATGGGT
AATGTAGTGTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(273-395)

Type II secretion system (T2SS), protein F (T2SSF)

(70-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7T0RNN2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

58.04

98.759

0.573
  pilC Acinetobacter baumannii D1279779

53.102

100

0.531
  pilC Acinetobacter baylyi ADP1

52.513

98.759

0.519
  pilC Legionella pneumophila strain ERS1305867

51.637

98.511

0.509
  pilC Vibrio cholerae strain A1552

46.096

98.511

0.454
  pilC Vibrio campbellii strain DS40M4

42.928

100

0.429
  pilG Neisseria meningitidis 44/76-A

42.184

100

0.422
  pilG Neisseria gonorrhoeae MS11

41.935

100

0.419
  pilC Thermus thermophilus HB27

36.908

99.504

0.367

Multiple sequence alignment