Detailed information    

insolico Bioinformatically predicted

Overview

Name   amiA   Type   Regulator
Locus tag   SP5448_RS01335 Genome accession   NZ_CP008776
Coordinates   251439..253409 (+) Length   656 a.a.
NCBI ID   WP_011285389.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain 5448     
Function   internalize XIP (predicted from homology)   
Competence regulation

Genomic Context

Location: 246439..258409
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SP5448_RS01315 (SP5448_01380) sufU 246485..246964 (+) 480 WP_002986018.1 Fe-S cluster assembly sulfur transfer protein SufU -
  SP5448_RS01320 (SP5448_01385) sufB 246957..248375 (+) 1419 WP_010921889.1 Fe-S cluster assembly protein SufB -
  SP5448_RS01325 (SP5448_01390) - 248527..249708 (-) 1182 WP_015055912.1 serine hydrolase -
  SP5448_RS01330 (SP5448_01395) pbp3 249876..251108 (-) 1233 WP_010921890.1 D-alanyl-D-alanine carboxypeptidase PBP3 -
  SP5448_RS01335 (SP5448_01400) amiA 251439..253409 (+) 1971 WP_011285389.1 peptide ABC transporter substrate-binding protein Regulator
  SP5448_RS01340 (SP5448_01405) amiC 253474..254976 (+) 1503 WP_010921891.1 ABC transporter permease Regulator
  SP5448_RS01345 (SP5448_01410) amiD 254976..255902 (+) 927 WP_010921892.1 oligopeptide ABC transporter permease OppC Regulator
  SP5448_RS01350 (SP5448_01415) amiE 255911..256981 (+) 1071 WP_010921893.1 ABC transporter ATP-binding protein Regulator
  SP5448_RS01355 (SP5448_01420) amiF 256974..257897 (+) 924 WP_002986000.1 ABC transporter ATP-binding protein Regulator
  SP5448_RS09980 - 257935..258024 (-) 90 WP_077707078.1 IS3 family transposase -

Sequence

Protein


Download         Length: 656 a.a.        Molecular weight: 72102.60 Da        Isoelectric Point: 5.1964

>NTDB_id=124123 SP5448_RS01335 WP_011285389.1 251439..253409(+) (amiA) [Streptococcus pyogenes strain 5448]
MKKSKWLAAVSVAILSVSALAACGNKNASGGSEATKTYKYVFVNDPKSLDYILTNGGGTTDVITQMVDGLLENDEYGNLV
PSLAKDWKVSKDGLTYTYTLRDGVSWYTADGEEYAPVTAEDFVTGLKHAVDDKSDALYVVEDSIKNLKAYQNGEVDFKEV
GVKALDDKTVQYTLNKPESYWNSKTTYSVLFPVNAKFLKSKGKDFGTTDPSSILVNGAYFLSAFTSKSSMEFHKNENYWD
AKNVGIESVKLTYSDGSDPGSFYKNFDKGEFSVARLYPNDPTYKSAKKNYADNITYGMLTGDIRHLTWNLNRTSFKNTKK
DPAQQDAGKKALNNKDFRQAIQFAFDRASFQAQTAGQDAKTKALRNMLVPPTFVTIGESDFGSEVEKEMAKLGDEWKDVN
LADAQDGFYNPEKAKAEFAKAKEALTAEGVTFPVQLDYPVDQANAATVQEAQSFKQSVEASLGKENVIVNVLETETSTHE
AQGFYAETPEQQDYDIISSWWGPDYQDPRTYLDIMSPVGGGSVIQKLGIKAGQNKDVVAAAGLDTYQTLLDEAAAITDDN
DARYKAYAKAQAYLTDNAVDIPVVALGGTPRVTKAVPFSGGFSWAGSKGPLAYKGMKLQDKPVTVKQYEKAKEKWMKAKA
KSNAKYAEKLADHVEK

Nucleotide


Download         Length: 1971 bp        

>NTDB_id=124123 SP5448_RS01335 WP_011285389.1 251439..253409(+) (amiA) [Streptococcus pyogenes strain 5448]
ATGAAGAAAAGTAAATGGTTGGCAGCTGTAAGTGTTGCGATCTTGTCAGTATCCGCTTTGGCAGCTTGTGGTAATAAAAA
TGCTTCAGGTGGCTCAGAAGCTACAAAAACCTACAAGTACGTTTTTGTTAACGATCCAAAATCATTGGATTATATTTTGA
CTAATGGCGGTGGAACGACTGATGTGATAACACAAATGGTTGATGGTCTTTTGGAAAACGATGAGTATGGTAATTTAGTA
CCATCACTTGCTAAAGATTGGAAGGTTTCAAAAGACGGTCTGACTTATACTTATACTCTTCGCGATGGTGTCTCTTGGTA
TACGGCTGATGGTGAAGAATATGCCCCAGTAACAGCAGAAGATTTTGTGACTGGTTTGAAGCACGCGGTTGACGATAAAT
CAGATGCTCTTTACGTTGTTGAAGATTCAATAAAAAACTTAAAGGCTTACCAAAATGGTGAAGTAGATTTTAAAGAAGTT
GGTGTCAAAGCCCTTGACGATAAAACTGTTCAGTATACTTTGAACAAGCCTGAAAGCTACTGGAATTCAAAAACAACTTA
TAGTGTGCTTTTCCCAGTTAATGCGAAATTTTTGAAGTCAAAAGGTAAAGATTTTGGTACAACCGATCCATCATCAATCC
TTGTTAATGGTGCTTACTTCTTGAGCGCCTTCACCTCAAAATCATCTATGGAATTCCATAAAAATGAAAACTACTGGGAT
GCTAAGAATGTTGGGATAGAATCTGTTAAATTGACTTACTCAGATGGTTCAGACCCAGGTTCGTTCTACAAGAACTTTGA
CAAGGGTGAGTTCAGCGTTGCACGACTTTACCCAAATGACCCTACCTACAAATCAGCTAAGAAAAACTATGCTGATAACA
TTACTTACGGAATGTTGACTGGAGATATCCGTCATTTAACATGGAATTTGAACCGTACTTCTTTCAAAAACACTAAGAAA
GACCCTGCACAACAAGATGCCGGTAAGAAAGCTCTTAACAACAAGGATTTTCGTCAAGCTATTCAGTTTGCTTTTGACCG
AGCGTCATTCCAAGCACAAACTGCAGGTCAAGATGCCAAAACAAAAGCCTTACGTAACATGCTTGTCCCACCAACATTTG
TGACCATTGGAGAAAGTGATTTTGGTTCAGAAGTTGAAAAGGAAATGGCAAAACTTGGGGATGAATGGAAAGACGTTAAC
TTAGCTGATGCTCAAGATGGTTTCTATAATCCTGAAAAAGCAAAAGCTGAGTTTGCAAAAGCCAAAGAAGCTTTAACAGC
TGAAGGTGTAACCTTCCCAGTTCAATTAGATTACCCTGTTGACCAAGCAAACGCAGCAACTGTTCAGGAAGCCCAGTCTT
TCAAACAATCTGTTGAAGCATCTCTTGGTAAAGAGAATGTCATTGTCAATGTTCTTGAAACAGAAACATCAACTCACGAA
GCCCAAGGCTTCTATGCTGAGACCCCAGAACAACAAGACTACGATATCATTTCATCATGGTGGGGACCAGACTATCAAGA
TCCACGGACCTACCTTGACATCATGAGTCCAGTAGGTGGTGGATCTGTTATCCAAAAACTTGGAATCAAAGCAGGTCAAA
ATAAGGATGTTGTGGCAGCTGCAGGCCTTGATACCTACCAAACTCTTCTTGATGAAGCAGCAGCAATTACAGACGACAAC
GATGCGCGCTATAAAGCTTACGCAAAAGCACAAGCCTACCTTACAGATAATGCCGTAGATATTCCAGTTGTGGCATTGGG
TGGCACTCCACGAGTTACTAAAGCCGTTCCATTTAGCGGGGGCTTCTCTTGGGCAGGGTCTAAAGGTCCTCTAGCATATA
AAGGAATGAAACTTCAAGACAAACCTGTCACAGTAAAACAATACGAAAAAGCAAAAGAAAAATGGATGAAAGCAAAGGCT
AAGTCAAATGCAAAATATGCTGAGAAGTTAGCTGATCACGTTGAAAAATAA

Domains

Predicted by InterproScan.

Bacterial extracellular solute-binding proteins, family 5 Middle (SBP_bac_5)

(79-515)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  amiA Streptococcus salivarius strain HSISS4

51.135

100

0.515
  amiA3 Streptococcus thermophilus LMG 18311

49.849

100

0.503
  amiA3 Streptococcus thermophilus LMD-9

49.547

100

0.5

Multiple sequence alignment