Detailed information
Bioinformatically predicted
Overview
| Name | pilA | Type | Machinery gene |
| Locus tag | C645_RS02020 | Genome accession | NZ_CP008740 |
| Coordinates | 411430..411879 (-) | Length | 149 a.a. |
| NCBI ID | WP_005656280.1 | Uniprot ID | A0A0H3PDQ7 |
| Organism | Haemophilus influenzae 2019 | ||
| Function | type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake |
||
Genomic Context
Location: 406430..416879
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| C645_RS02000 (C645_02025) | rho | 406817..408079 (+) | 1263 | WP_005648966.1 | transcription termination factor Rho | - |
| C645_RS02005 (C645_02030) | pilD | 408133..408825 (-) | 693 | WP_046067576.1 | prepilin peptidase | Machinery gene |
| C645_RS02010 (C645_02035) | pilC | 408822..410042 (-) | 1221 | WP_046067577.1 | type II secretion system F family protein | Machinery gene |
| C645_RS02015 (C645_02040) | pilB | 410039..411433 (-) | 1395 | WP_005656265.1 | GspE/PulE family protein | Machinery gene |
| C645_RS02020 (C645_02045) | pilA | 411430..411879 (-) | 450 | WP_005656280.1 | prepilin-type N-terminal cleavage/methylation domain-containing protein | Machinery gene |
| C645_RS02025 (C645_02050) | ampD | 411994..412554 (+) | 561 | WP_005648974.1 | 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD | - |
| C645_RS02030 (C645_02055) | corC | 413175..414074 (+) | 900 | WP_005656283.1 | CNNM family magnesium/cobalt transport protein CorC | - |
| C645_RS02035 (C645_02060) | lnt | 414097..415626 (+) | 1530 | WP_079997635.1 | apolipoprotein N-acyltransferase | - |
| C645_RS02040 (C645_02065) | rsmE | 415676..416413 (+) | 738 | WP_005689496.1 | 16S rRNA (uracil(1498)-N(3))-methyltransferase | - |
Sequence
Protein
Download Length: 149 a.a. Molecular weight: 15684.12 Da Isoelectric Point: 9.3906
>NTDB_id=123949 C645_RS02020 WP_005656280.1 411430..411879(-) (pilA) [Haemophilus influenzae 2019]
MKLTTQQTLKKGFTLIELMIVIAIIAILATIAIPSYQNYTKKASVSELLQASAPYKADVELCVYSTNETTNCTGGKNGIA
ADITTAKGYVASVKTQSGGITVKGNGTLANMEYILQAKGNATAGVTWTTTCKGTDASLFPANFCRSVTK
MKLTTQQTLKKGFTLIELMIVIAIIAILATIAIPSYQNYTKKASVSELLQASAPYKADVELCVYSTNETTNCTGGKNGIA
ADITTAKGYVASVKTQSGGITVKGNGTLANMEYILQAKGNATAGVTWTTTCKGTDASLFPANFCRSVTK
Nucleotide
Download Length: 450 bp
>NTDB_id=123949 C645_RS02020 WP_005656280.1 411430..411879(-) (pilA) [Haemophilus influenzae 2019]
ATGAAATTAACAACACAGCAAACCTTGAAAAAAGGTTTTACATTAATCGAGCTAATGATTGTGATTGCAATTATTGCTAT
TTTAGCCACTATCGCAATTCCTTCTTATCAAAATTATACCAAAAAAGCTTCGGTATCCGAATTACTGCAAGCATCTGCAC
CTTATAAGGCTGATGTGGAATTATGTGTATATAGCACAAATGAAACAACAAACTGTACGGGTGGAAAAAATGGTATTGCA
GCTGATATTACAACAGCAAAAGGCTATGTAGCCTCAGTGAAAACTCAATCGGGTGGCATTACAGTAAAAGGGAATGGCAC
ATTGGCAAATATGGAATATATTTTGCAAGCTAAAGGTAATGCTACAGCAGGTGTAACTTGGACAACAACCTGCAAAGGAA
CGGATGCCTCTTTATTTCCAGCAAATTTTTGCAGAAGTGTCACAAAATGA
ATGAAATTAACAACACAGCAAACCTTGAAAAAAGGTTTTACATTAATCGAGCTAATGATTGTGATTGCAATTATTGCTAT
TTTAGCCACTATCGCAATTCCTTCTTATCAAAATTATACCAAAAAAGCTTCGGTATCCGAATTACTGCAAGCATCTGCAC
CTTATAAGGCTGATGTGGAATTATGTGTATATAGCACAAATGAAACAACAAACTGTACGGGTGGAAAAAATGGTATTGCA
GCTGATATTACAACAGCAAAAGGCTATGTAGCCTCAGTGAAAACTCAATCGGGTGGCATTACAGTAAAAGGGAATGGCAC
ATTGGCAAATATGGAATATATTTTGCAAGCTAAAGGTAATGCTACAGCAGGTGTAACTTGGACAACAACCTGCAAAGGAA
CGGATGCCTCTTTATTTCCAGCAAATTTTTGCAGAAGTGTCACAAAATGA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| pilA | Haemophilus influenzae Rd KW20 |
95.302 |
100 |
0.953 |
| pilA | Haemophilus influenzae 86-028NP |
91.946 |
100 |
0.919 |
| pilA | Glaesserella parasuis strain SC1401 |
54.054 |
99.329 |
0.537 |
| pilA2 | Legionella pneumophila strain ERS1305867 |
40.667 |
100 |
0.409 |
| pilA2 | Legionella pneumophila str. Paris |
40.845 |
95.302 |
0.389 |
| pilA | Vibrio campbellii strain DS40M4 |
40.426 |
94.631 |
0.383 |