Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilD   Type   Machinery gene
Locus tag   C645_RS02005 Genome accession   NZ_CP008740
Coordinates   408133..408825 (-) Length   230 a.a.
NCBI ID   WP_046067576.1    Uniprot ID   -
Organism   Haemophilus influenzae 2019     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 403133..413825
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C645_RS01965 (C645_01990) - 404449..404655 (-) 207 WP_005656254.1 heavy-metal-associated domain-containing protein -
  C645_RS01970 (C645_01995) - 404729..404935 (-) 207 WP_005656255.1 heavy-metal-associated domain-containing protein -
  C645_RS01975 (C645_02000) - 405009..405215 (-) 207 WP_005656257.1 heavy-metal-associated domain-containing protein -
  C645_RS01980 (C645_02005) - 405289..405495 (-) 207 WP_005660027.1 heavy-metal-associated domain-containing protein -
  C645_RS01985 (C645_02010) - 405569..405775 (-) 207 WP_005689491.1 heavy-metal-associated domain-containing protein -
  C645_RS01990 (C645_02015) cueR 405852..406238 (+) 387 WP_005648963.1 Cu(I)-responsive transcriptional regulator -
  C645_RS01995 (C645_02020) metJ 406252..406569 (-) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  C645_RS02000 (C645_02025) rho 406817..408079 (+) 1263 WP_005648966.1 transcription termination factor Rho -
  C645_RS02005 (C645_02030) pilD 408133..408825 (-) 693 WP_046067576.1 prepilin peptidase Machinery gene
  C645_RS02010 (C645_02035) pilC 408822..410042 (-) 1221 WP_046067577.1 type II secretion system F family protein Machinery gene
  C645_RS02015 (C645_02040) pilB 410039..411433 (-) 1395 WP_005656265.1 GspE/PulE family protein Machinery gene
  C645_RS02020 (C645_02045) pilA 411430..411879 (-) 450 WP_005656280.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  C645_RS02025 (C645_02050) ampD 411994..412554 (+) 561 WP_005648974.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26596.64 Da        Isoelectric Point: 7.7420

>NTDB_id=123946 C645_RS02005 WP_046067576.1 408133..408825(-) (pilD) [Haemophilus influenzae 2019]
MIYFAMFLLGGILGIALWFYLSGFITRLQQEIYVTYVELFPQNFLSFQPSFSSIQQKKCGHILRYFLSVGVGFIFLQIAF
KDSIFAIWLGLTLIILWAISYLDWDYQLISMTPCLWLLTLGLFGADNDFSLLTLSESIKSAASFFIVFYAIYWIAKFYYG
KEAFGPGDYWLAMALGSFIHLETLPYFLLLASVLGICFSLIHRKKKEFLPFAPFMNLSAIIIYLVKYYGY

Nucleotide


Download         Length: 693 bp        

>NTDB_id=123946 C645_RS02005 WP_046067576.1 408133..408825(-) (pilD) [Haemophilus influenzae 2019]
ATGATTTACTTCGCAATGTTTTTATTAGGTGGCATCTTAGGGATCGCATTGTGGTTCTACCTATCTGGTTTTATTACGCG
TTTGCAGCAAGAGATTTATGTGACTTACGTTGAATTATTTCCACAAAACTTTCTGTCATTTCAGCCTAGCTTTTCCTCTA
TTCAACAAAAAAAGTGCGGTCATATTTTGAGATATTTTTTAAGTGTTGGGGTAGGATTTATATTTTTACAAATTGCCTTC
AAGGACTCTATTTTCGCTATATGGCTAGGGCTCACACTTATTATCCTTTGGGCAATTAGTTATCTTGATTGGGATTATCA
ACTTATTTCTATGACTCCCTGTTTATGGTTACTTACTCTCGGTTTATTTGGCGCAGACAATGACTTTTCATTGCTTACGT
TATCTGAAAGCATAAAAAGTGCGGCTAGTTTTTTTATTGTTTTCTACGCAATCTATTGGATTGCAAAATTCTATTACGGA
AAAGAAGCCTTTGGACCGGGAGATTATTGGCTAGCAATGGCATTAGGAAGTTTTATTCATTTAGAAACCTTACCGTACTT
TTTATTATTAGCTTCAGTTCTTGGAATATGTTTTTCGCTTATTCATAGGAAGAAAAAAGAATTTTTACCTTTTGCCCCTT
TTATGAACTTATCGGCTATCATCATTTATCTCGTCAAATATTACGGATATTAA

Domains

Predicted by InterproScan.

Type IV leader peptidase family (Peptidase_A24)

(92-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilD Haemophilus influenzae 86-028NP

90

100

0.9
  pilD Haemophilus influenzae Rd KW20

89.565

100

0.896

Multiple sequence alignment